Auf der Suche nach Ursachen von #LongCOVID hat ein Team am @ciim-hannover.bsky.social Immunzellen von Patient:innen analysiert. Sie fanden molekulare Veränderungen in #Monozyten, die mit der Schwere von Fatigue, Atemwegssymptomen & Entzündungswerten korrelieren.
www.helmholtz-hzi.de/media-center...

Very pleased to have our long COVID work published! Summary to follow soon.

GitHub - CiiM-Bioinformatics-group/scImmuAging Contribute to CiiM-Bioinformatics-group/scImmuAging development by creating an account on GitHub.

Das Tool „Single-Cell Immune Aging Clock“ der Wissenschaftler:innen des @ciim-hannover.bsky.social steht auf Github für weiterführende Forschungsprojekte frei zur Verfügung: github.com/CiiM-Bioinfo...

„Aging Clock“ enthüllt Alterungsprozesse in Immunzellen HZI-Team erstellt KI-basiertes Computermodell, das Altern auf Zellebene erstmals sichtbar macht

Forscher:innen um Yang Li am @ciim-hannover.bsky.social haben ein KI-basiertes Computermodell entwickelt, das Immunalterung auf Zellebene sichtbar macht. Für die Studie @natureaging.bsky.social haben sie Transkriptom-Daten versch. Immunzelltypen untersucht. www.helmholtz-hzi.de/media-center...

A comment that shouldn’t need making about the estimated 400m globally with #LongCovid: just because we don’t have an agreed diagnostic test, your GP hasn’t made the diagnosis, you weren’t hospitalised with severe COVID19, doesn’t mean your condition is *psychosomatic*. It’s real pathophysiology

Single-cell immune aging clocks reveal inter-individual heterogeneity during infection and vaccination - Nature Aging Immune system function changes substantially with age. In this study, the authors present single-cell transcriptomic aging clocks revealing immune-cell-specific age acceleration that is shaped by infe...

Single cell ageing clock looking at inter-individual variability and it's implications in infection and vaccination. @ciim-hannover.bsky.social #aging #sc @helmholtzhzi.bsky.social
www.nature.com/articles/s43...

Global health researcher Madhukar Pai believes scientific innovations must reach everyone Working toward a more diverse, inclusive, and equitable future for global health with Dr. Pai.

'To me, innovations mean little if they cannot save lives (...) Yes, mRNA vaccines are great, Nobel-prize-winning innovations, but they never reached most Global South countries. To date, they continue to remain a monopoly of Big Pharma and rich nations that hoarded vaccines.'
@madhupai.bsky.social

A panoramic view of cell population dynamics in mammalian aging To elucidate aging-associated cellular population dynamics, we present PanSci, a single-cell transcriptome atlas profiling over 20 million cells from 623 mouse tissues across different life stages, se...

Immune cells change in proportions with age - naive go down, effector go up. www.science.org/doi/10.1126/...

Finally moved to #bluesky and loving it! Glad to find all the scientists and connect! Hoping for this to be the place for having good discussions again!