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Posts by Leonard Frach

Vacatures - Postdoctoral researcher specialising in gene–environment interplay - Amsterdam UMC Ready to unravel the complex interplay between genes and environment shaping health and society? Join our interdisciplinary team analyzing large-scale genomic data across Europe. Are you eager to contribute to groundbreaking research on health and social inequalities?

Me & @aysuo.bsky.social are hiring a postdoc to study gene–environment interplay in health & social inequalities 🧬

You'll analyze genomic data as part of a collaboration with Uppsala & Oslo at @amsterdamumc.bsky.social (NL)

werkenbij.amsterdamumc.org/en/vacatures...

Please RT for karma points ♥️

4 weeks ago 30 33 0 4
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Untangling genetic and environmental pathways to language and reading development: Integrating social and genetic data from longitudinal cohort studies Principal Supervisor: Dr Tim Morris (UCL) Co-Supervisors: Dr Emma Meaburn (Birkbeck); Professor Bonamy Oliver (UCL) Project Description Language and reading skills are key drivers of educational su…

🚨We have a fully-funded PhD scholarship (UCL/Birkbeck) starting October 2026 to look at how genetic, family, and social factors shape children’s language and literacy development. **Deadline 29th March**. Further details at bit.ly/40B2Wrx, please do get in touch if you are interested!

1 month ago 0 2 0 0

We have a new preprint online describing the molecular genetic and epigenetic data in the German TwinLife Study (TwinSNPs and TECS samples). Together with shared first authors @charlottepahnke.bsky.social & @aliciaschowe.bsky.social
More detailed thread coming soon!
www.biorxiv.org/content/10.6...

1 month ago 7 1 1 0

Thanks to all other co-authors A. Andreas, M. Deppe, @janainstinske.bsky.social, C. Maj, @mirkomincho.bsky.social , L. Wiesmann, C. Kandler, B. Mönkediek, F. Spinath, N. Nöthen, E. Binder, D. Czamara & A. Forstner, and to all TwinLife participants and to the funders of these projects @dfg.de

1 month ago 0 0 0 0

We have a new preprint online describing the molecular genetic and epigenetic data in the German TwinLife Study (TwinSNPs and TECS samples). Together with shared first authors @charlottepahnke.bsky.social & @aliciaschowe.bsky.social
More detailed thread coming soon!
www.biorxiv.org/content/10.6...

1 month ago 7 1 1 0
Host control of persistent Epstein–Barr virus infection Nature - Host control of persistent Epstein–Barr virus infection

🖨️ Hot off the press 🍾 :
I am super excited to share that our article on the host control of persistent EBV infection has just been published in Nature Magazine, in an accelerated article preview version:

rdcu.be/e4Lg8

2 months ago 25 14 2 1
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Just posted a new preprint! We uncovered reproducible symptom‑based subtypes of depression.
Findings include:
• melancholic, atypical & psychomotor subtypes
• links between insomnia + weight gain clusters and asthma
• psychomotor clusters associated with Parkinson’s disease
🔗 doi.org/10.64898/202...

2 months ago 2 1 0 0
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Researcher in Post-Pandemic Youth Mental Health  (294258) | University of Oslo Job title: Researcher in Post-Pandemic Youth Mental Health  (294258), Employer: University of Oslo, Deadline: Thursday, March 5, 2026

I'm hiring #PROMENTA @uio.no: Researcher (PhD) in post-pandemic youth mental health (#NordForsk consortium SISU/PRISM).
#MoBa #genetics + registry data -> gene-environment interactions. Please share!
www.jobbnorge.no/en/available... @ki.se @haskolinn.bsky.social @thlorg.bsky.social

2 months ago 6 6 0 0
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<em>Journal of Child Psychology and Psychiatry</em> | ACAMH Pediatric Journal | Wiley Online Library Background From a functionalist perspective, parenting behaviors have adaptive functions and are partly expressions of genetic variation. Maternal genes that have effects on children are often refer...

Article alert!🚨
1/11 Parents matter - and we can quantify part of that influence genetically. Our new JCPP paper on multivariate indirect maternal genetic effects across internalizing and externalizing symptoms. doi.org/10.1111/jcpp...
#jcpp @uio.no @unioslo-svfak.bsky.social @unioslo-uv.bsky.social

2 months ago 21 8 2 1
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I've used Lavaan almost every (work)day for 15 years, but this open source labour of love has never received proper institutional support. I'm delighted to be a small part of an 1.5M OpenScienceNL award, led by Jorgensen, to completely revamp and futureproof Lavaan www.openscience.nl/en/news/45-p...

4 months ago 266 62 10 6
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Mapping the genetic landscape across 14 psychiatric disorders - Nature Genomic analyses applied to 14 childhood- and adult-onset psychiatric disorders identifies five underlying genomic factors that explain the majority of the genetic variance of the individual disorders...

1/4 Thrilled to be sharing new work published today in Nature describing the third wave of results from the PGC Cross-Disorder Group. This reflects a massive group effort to examine shared and unique genetic signal across >1 million cases for 14 psychiatric disorders. www.nature.com/articles/s41...

4 months ago 122 51 2 7
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🚨 SynthNet is out 🚨
Researchers propose new constructs and measures faster than anyone can track. We (@anniria.bsky.social @ruben.the100.ci) built a search engine to check what already exists and help identify redundancies; indexing 74,000 scales from ~31,500 instruments in APA PsycTests. 🧵1/3

4 months ago 158 86 3 3
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Genetic associations with educational fields - Nature Genetics Genome-wide analyses of 10 educational fields identify 17 associated loci. Analysis of genetic clustering across specializations identifies two key dimensions that show genetic overlap with personalit...

1/ 🚨New paper in Nature Genetics

Genetic factors are associated with the educational fields people study, from arts to engineering.

Article: www.nature.com/articles/s41...
FAQ: www.thehastingscenter.org/genomic-find...

5 months ago 48 18 1 7
BGA Job Listings - Behavior Genetics Association

We currently have multiple job openings (post-doc/assistant prof/associate prof) listed on our website, see thread below if you don't want to miss out!
bga.org/content.aspx...

5 months ago 2 3 1 0
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Postdoctoral Position in Social Science Genomics | Max Planck Research Group Biosocial

We have an open postdoc position in Social Science Genomics in Berlin!

Includes gene-environment interplay within German population cohorts & experimental online survey studies to probe public perceptions of potential DNA biomarker applications

🔗 www.mpib-berlin.mpg.de/2196134/2025...

5 months ago 18 21 0 0
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Looking for an *amazing* postdoc supervisor? 👀
Excellent opportunity with the one and only @jessiebaldwin.bsky.social

6 months ago 1 0 0 0
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Research Fellow in Mental Health at UCL Apply for the Research Fellow in Mental Health role on jobs.ac.uk, the top job board for academic positions in higher education. View details and apply now.

I'm hiring! ✨ Looking for a Research Fellow to study environmental factors that mitigate intergenerational transmission of mental health.

3-year post at UCL @uclbrainscience.bsky.social with great opportunities for training, collaboration & exciting science!

🔗 Apply: www.jobs.ac.uk/job/DOZ633/r...

6 months ago 17 15 1 3
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New paper out at the Journal of Psychopathology and Clinical Science!

We examined unconditional & event-related changes in pathological vs normal-range personality using 4 metrics to compare their developmental links, how these vary with life events, and whether unique effects emerge across metrics

7 months ago 24 10 1 1

I'm looking for a PhD student to do some trailblazing at the frontier of personality genomics and lifespan gene-environment transactions (start Fall 2026)! If you want to work with me: psychology.msu.edu/graduatestud...
(PS @drmeltemyucel.bsky.social is taking a student too, in moral psych/dev!)

7 months ago 30 29 1 3
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The elusive neural signature of emotion regulation capabilities: evidence from a large-scale consortium Cognitive reappraisal is a fundamental emotion regulation strategy for mental and physical well-being, but how its neural mechanisms relate to individual differences remains poorly understood. In a co...

BIG PREPRINT🔬

In a newly founded consortium we show that we barely know anything about the neurobiology underlying emotion regulation capacity! (40 fmri samples, N=2175)

So, time-out for prefrontal cortex explanations!

And we also show why this might be the case 🧵

www.biorxiv.org/content/10.1...

8 months ago 5 1 1 1
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Genome-wide association study of borderline personality disorder identifies 11 loci and highlights shared risk with mental and somatic disorders We conducted the largest genome-wide meta-analysis of borderline personality disorder (BPD) to date, with a discovery sample of 12,339 cases and 1,041,717 controls, and a replication study of 685 case...

An updated preprint of our Borderline Personality Disorder GWAS is now online:
www.medrxiv.org/content/10.1...

8 months ago 5 2 1 0
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🚨 Our parent-of-origin study is out in Nature! 🧬
Maternal and paternal alleles can have distinct — even opposite — effects on human traits, revealing a hidden layer of genetic architecture that standard GWAS miss.
🔗 www.nature.com/articles/s41...

Highlights below!

8 months ago 117 55 2 5
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New pre-print online: Imputing parental genotypes through Mendelian Imputation: Ethical and Legal Considerations
osf.io/preprints/ps...

8 months ago 13 7 2 4
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Very exciting preprint by @axel-schmidt.bsky.social, @kuludwig.bsky.social and team!
Check out Kerstin's thread for overview

8 months ago 4 2 0 0

Very exciting preprint by @axel-schmidt.bsky.social, @kuludwig.bsky.social and team!
Check out Kerstin's thread for overview

8 months ago 4 2 0 0
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Genetic impacts on within-pair DNA methylation variance in monozygotic twins capture gene-environment interactions and cell-type effects Background Genetic variants that are associated with phenotypic variability, or variance quantitative trait loci (vQTLs), have been detected for multiple human traits. Gene-environment interactions ca...

New preprint by Xiaopu Zhang!
www.biorxiv.org/content/10.1...
@jordanatbell.bsky.social @ntrbiopsy.bsky.social

8 months ago 4 3 0 1

🔔Paper alert! Extremely excited to share a preprint from our lab! Spearheaded by @axel-schmidt.bsky.social, a super talented medical & computational geneticist, we studied latent Epstein-Barr virus (EBV) infection at population-scale.

Interested in how this works & what we found? Read along! 👇

9 months ago 22 12 1 2

Our project, looking at the genetic relationships between immune diseases and psychiatric disorders, has finally been published! Now with gene expression analyses as well as additional sensitivity analyses, thanks to reviewers. Find the full article here: www.nature.com/articles/s41...

9 months ago 28 5 2 0
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PHD Position at the Department of Developmental and Educational Psychology (m/f/d)

PhD position in my group at @fau.de, as part of my @erc.europa.eu Consolidator project PAR2. German is not essential but an interest in social science genetics would be great! Sharing would be much appreciated ❤️

www.jobs.fau.de/jobs/phd-pos...

9 months ago 10 10 0 1