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Posts by john sakon

🚨Excited to share my first @biorxivpreprint.bsky.social🚨 with the amazing Smith lab, @jbarbosa.org and Albert Compte who made this work possible.

We show that 🐒prefrontal hemispheres combine redundancy (for precision) & weak connections (for capacity) for supporting spatial working memory (WM). 1/🧵

1 year ago 33 13 1 1
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Good on The Strokes for not being shy at Coachella

2 days ago 2 0 0 0
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Pancreatic cancer mRNA vaccine shows lasting results in an early trial Scientists caution that more research is needed, but nearly all of the patients who responded to the personalized vaccine are still alive six years later.

"Pancreatic cancer mRNA vaccine shows lasting results in an early trial: Scientists caution that more research is needed, but nearly all of the patients who responded to the personalized vaccine are still alive six years later."

2 days ago 9705 2892 157 599
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Happy Tax Day, New York. We’re taxing the rich.

5 days ago 36212 7629 820 1579
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how you know zohran mamdani is doing well. the billionaires and capitalist class fucking us all over are scared

4 days ago 3858 432 87 30
Work in Progress: How we're tackling Sidewalk Sheds (with John Wilson)
Work in Progress: How we're tackling Sidewalk Sheds (with John Wilson) YouTube video by NYC Mayor's Office

No one likes unnecessary scaffolding. Thankfully, we have a plan — and John Wilson is here to help break it down.

1 week ago 2976 376 79 217

“Predictably” doing *heavy* work here

1 week ago 0 0 0 0

What do you want Democrats to do? There's nothing they can do. However, it's very important you continue to vote for them and give them money, as they continue to do nothing.

1 week ago 2438 409 58 45
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I Work Very Hard, And I Would Like To Try Cake

By A Horse

Hello. I am a horse. I work very hard at my job of being a horse. When humans say move the heavy thing, I move the heavy thing. When humans sit on top of me and pull on my head, I carry them where they want to go. The main food the humans give me is hay and oats. But I am thinking it would be nice to have a different food.

I am thinking I would like to try cake.

Yes, yes. Cake. I know all about it. When humans eat cake, it is in glad times. It is the food for a celebration, such as when a woman becomes 47. I have seen cake on the Fourth of July. When humans have a cake, they stand around it and clap hands and smile and say happy birthday at each other. Sometimes there are beautiful markings on a cake, such as balloons or a pink shape.

Sometimes the top of a cake is on fire and a boy must blow on the fire with mouth wind. This is the scariest cake. I do not want this kind. But I will eat any other cake. Any cake that is not the fire cake that tries to kill the boy.

Please understand: I do not get money for doing work. I do not get to go inside the house. All I am either doing my horse job or standing in my pen or eating food off the floor. I always do these things. But I have never once gotten cake and I would like it very much.

I have noticed that human children get to eat cake. But I am bigger than the children. I am more helpful to the farm. Children do not move the heavy things like me or let anyone ride on them. And yet they get cake. Maybe the humans will realize this. Maybe they will say, "You  know who deserves cake? That horse. That horse whose back we are always on."

Every day I dream about what it will be like if I get to eat cake. Here is what will happen. First, I will walk to the cake and putt my nose at it like hrrfff to make and stomping my hooves to make sure it is not a snake. Then I will trot in a circle to show that I am a horse and I am large. After that, I will nuzzle the cake to …

I Work Very Hard, And I Would Like To Try Cake By A Horse Hello. I am a horse. I work very hard at my job of being a horse. When humans say move the heavy thing, I move the heavy thing. When humans sit on top of me and pull on my head, I carry them where they want to go. The main food the humans give me is hay and oats. But I am thinking it would be nice to have a different food. I am thinking I would like to try cake. Yes, yes. Cake. I know all about it. When humans eat cake, it is in glad times. It is the food for a celebration, such as when a woman becomes 47. I have seen cake on the Fourth of July. When humans have a cake, they stand around it and clap hands and smile and say happy birthday at each other. Sometimes there are beautiful markings on a cake, such as balloons or a pink shape. Sometimes the top of a cake is on fire and a boy must blow on the fire with mouth wind. This is the scariest cake. I do not want this kind. But I will eat any other cake. Any cake that is not the fire cake that tries to kill the boy. Please understand: I do not get money for doing work. I do not get to go inside the house. All I am either doing my horse job or standing in my pen or eating food off the floor. I always do these things. But I have never once gotten cake and I would like it very much. I have noticed that human children get to eat cake. But I am bigger than the children. I am more helpful to the farm. Children do not move the heavy things like me or let anyone ride on them. And yet they get cake. Maybe the humans will realize this. Maybe they will say, "You know who deserves cake? That horse. That horse whose back we are always on." Every day I dream about what it will be like if I get to eat cake. Here is what will happen. First, I will walk to the cake and putt my nose at it like hrrfff to make and stomping my hooves to make sure it is not a snake. Then I will trot in a circle to show that I am a horse and I am large. After that, I will nuzzle the cake to …

The horse op-ed is an instant classic. I can't tell you how much joy this piece gives me.

It should be taught in every introductory writing class in no small part because the horse arguments are so compelling. "I have noticed that human children get to eat cake. But I am bigger than the children."

2 weeks ago 16924 5834 259 695
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a man in a blue shirt and tie is dancing in front of a group of people . ALT: a man in a blue shirt and tie is dancing in front of a group of people .

Hell yeah Uncle Michael!!

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Tweet that says:

genie: please no
millipede: more legs

Tweet that says: genie: please no millipede: more legs

This one is a no brainer for me

2 weeks ago 1835 145 4 2
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very normal country

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The party of the rich just taxed the rich in WA. Can that hold? About 8 in 10 of the Washington residents who will have to pay the new millionaire's income tax live in Democratic districts. Legislators there say their rich constituents are fine with it.

Washington state passed a tax on millionaires. A lot of the usual suspects have been screaming & tearing their hair out & warning of apocalypse.

But the actual rich people of Washington? Turns out they are mostly Democrats & they mostly support it!

2 weeks ago 806 223 17 13
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Public communication alters private confidence Andreassen et al. demonstrate that confidence exhibited in public affects our private assessment of confidence.

Public communication alters private confidence - cool study from @danieljamesyon.bsky.social and team

www.cell.com/current-biol...

2 weeks ago 14 8 1 1
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"The way some of these other immigrants are getting treated in our country right now is a travesty and a disgrace... I think what’s going on in our country — what we’re doing to some of these amazing immigrants, is really unfortunate and it’s really sad." - Charles Barkley on CBS

3 weeks ago 12591 2365 263 556
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No one is ever held accountable for these pledges either. They’re just advertising until they go back on them.

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McMorrow whining about hasan

McMorrow whining about hasan

Mcmorrow last year saying Dems are too picky and need a Joe Rogan of the left.

Mcmorrow last year saying Dems are too picky and need a Joe Rogan of the left.

Note the names lol. Second article is from last year:

3 weeks ago 219 10 3 0

Last year: We need a Joe Rogan of the left!

This year: No not like that! I need them to sound like Kamala!

3 weeks ago 232 6 3 2

Could be. He sure is saying different things than Fetterman when you contrast speeches. But yes I dunno why he hasn’t directly addressed many of the claims…being charitable maybe his team thinks it’s a better strategy to ignore than bring to forefront (since even if fake guilt by association)

3 weeks ago 1 0 0 0
John Fetterman And The Progressive Switcheroo - SOME MORE NEWS
John Fetterman And The Progressive Switcheroo - SOME MORE NEWS YouTube video by Some More News

Fetterman was always this way the online left just wishcasted on a few things he said www.youtube.com/watch?v=28M_...

3 weeks ago 1 0 1 0

The Peacock between pitches Capital One Best Life Jennifer Garner ads—and the fact I had to write that very sentence—are singlehandedly continuing the decline in America’s life expectancy

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Computational framework to predict and shape human–machine interactions in closed-loop, co-adaptive neural interfaces - Nature Machine Intelligence Madduri et al. introduce a computational framework grounded in control and game theory to model co-adaptation between users and decoders in neural interfaces. This framework enables a principled desig...

If you're interested in emerging ideas in neural interfaces, I humbly suggest my lab's latest: www.nature.com/articles/s42...

Neural interfaces create dynamic interactions between the brain & devices. This means mean we need new engineering approaches beyond typical ML to "decode" a static brain

3 weeks ago 66 26 2 2

ok

3 weeks ago 0 0 0 0
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Government must deliver for working people—and every dollar in our budget should work as hard as they do.

That’s why I directed every agency to cut waste and help close our budget gap.

Here’s some of what we found.

3 weeks ago 4322 654 164 307

Abolish TSA

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🚨NEW PREPRINT (w/ Fleming Peck & Hongjing Lu)

"Spontaneous emergence of context-dependent statistical learning in humans and neural networks"

We are constantly predicting what will happen next. Yet the same cue can lead to different predictions depending on context.

How might this work...? 🧵1/8

3 weeks ago 36 14 1 0

No

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John Fetterman And The Progressive Switcheroo - SOME MORE NEWS
John Fetterman And The Progressive Switcheroo - SOME MORE NEWS YouTube video by Some More News

He was always this way and the left wishcasted on vagueness youtu.be/28M_zkoAGQM?...

1 month ago 0 0 0 0
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Sanders: People can't afford health care. People can't afford childcare. And this guy, in addition to giving tax breaks to billionaires, now wants to spend another $200 billion on a war that should never have been fought.

1 month ago 4374 1237 118 54