A skin-hypothalamus axis couples heat stress and metabolic dysfunction Heat stress activates a skin-hypothalamus axis via KLK14-dependent epigenetic reprogramming of LRRC7⁺ astrocytes, thereby exacerbating diet-induced metabolic dysfunction. Vitamin A reduces KLK14 level...

A skin-hypothalamus axis couples heat stress and metabolic dysfunction: Cell www.cell.com/cell/fulltex...

RFK Jr. just said HHS is "cleaning up the risk pool" (i.e., people who are unhealthy) to bring down healthcare costs.

Last week, two other drivers received sentences of four years or less for killing somebody with their cars. The 19-year-old had the history. I really wish some media outlet in town would look at sentencing guidelines, and what kind of departures from those are occurring in vehicular homicide cases.

Republican death panels.

Folks who never flew or cared about the flag: "This newfangled flag is [enter racist BS]. We can't change!"

Drove by and wondered what the hype was. I'll put it on my calendar.😂

Did the car have free will? Can they charge the car with vehicular homicide?

John Gurdon (1933-2025) John Gurdon was a towering figure in developmental biology, respected and admired throughout the world. His discovery, made when he was a PhD student, that the nuclei of differentiated cells retain th...

"Gurdon..claimed not to like reading at all – not even the scientific literature...He suggested it was his inability to understand anything complicated that led to the clarity of thought for which he was renowned" And of course a Nobel Prize.. journals.biologists.com/dev/article/...

I was filming crocodiles near birds in Costa Rica and the alligator got one. #tarcoles

And the Nixon masks in the movies worn by bank robbers and thugs.

But seriously, the experimental/avant garde jazz shows that come through town are pretty excellent. The Walker series had Mali Obomsawin and her group last Saturday at Icehouse. So good…errrh, “terrible”!

The mayor of Minneapolis didn’t really do anything except bloviate.

Society at large has become inured to automobile violence.

the penne opticon

So they will have to drive about 100 each way to either Rapid City or Scott’s Bluff probably. Chadron is pretty out there. Pine Ridge Hospital is closer so I wonder if that’s an option.

11:15 AM - 11:45 AM CDT Speaker AAN Lifetime Achievement Award for Clinically Relevant Research: What's the Deal with Parkinson's? Anthony E. Lang, MD, FAAN

Probably this:

It’s very exclusive.🤣 My wife attended that meeting in 2019 in Philly and I tagged along. I was only able to sneak in for a second.

Any advice on a stable and easy to adjust tripod for a spotting scope? I got an entry-level Vortex scope and my cheap camera tripod isn't stable enough, mostly due to the cheap ball head. I've been looking at the Vortex Mountain Pass (can't afford the carbon fiber models). #birds #Birds #birding

Is it a coincidence that Mr. "Whipple" wouldn't supply toilet paper?

I had a really nice lunch there earlier this year and it did seem they could expertly ratchet up the heat. For some reason, I really enjoyed their Kheer.

Practicing so I’m sure to not be mistaken when I ask for my senior discount.

Did you make it clear that you’d never squeezed the Charmin?

Looks like she's on the white track. 😅

This is impressive work to address primarily gun-related homicides. Meanwhile, St Paul has had four people killed by drivers through the end of March. SPPD appears to focusing on the right things. SP Public Works, MnDOT, and Ramsey County are lagging behind in addressing vehicular violence.

The truth is out there.

Probably a strategy to please the owner and get a pay raise. Ideological diversity, especially the head in the sand variety, is all the rage these days. With stuff like this he also positions himself well for a job at CBS.

I agree and I think it has deep roots. It’s been lurking in the food coop supplement sections and stores since the beginning and our own NIH propped it up starting in late 1991 when it launched the Office of Alternative Medicine (OAM).

🔥SEN. @ossoff.senate.gov : “Ivanka’s husband Jared Kushner’s on the Saudi payroll for $2 BILLION— as he leads 🇺🇸 diplomacy + asks sheikhs for billions more… Never have we seen so little effort to hide so much corruption. The Mar-a-Lago mafia taking corruption to spectacular new heights.”

I listened to that on tape so many times.

I'm not joking when I say mRNA technology is more important than "AI" and it's a tragedy we're throwing billions into one while our government is aggressively defunding the other.