Seeds for the different Kronos SPL-resistant lines(rSPLs) that accelerate wheat heading time are available without restrictions from GRIN-GLOBAL under accession numbers PI 707858 (rSPL-A3), PI707859 (rSPL-A4), PI 707860 (rSPL-A13), PI 707861 (rSPL-B3), and PI 707862 (rSPL-B13)
Our paper integrating the endogenous age pathway with the vernalization, photoperiod and GA pathways in the regulation of heading time in wheat is now published in The Plant Journal (open access). onlinelibrary.wiley.com/doi/epdf/10....
Our lab has just posted a review on wheat spike development, with an emphasis on the regulation of the number of spikelets per spike on bioRxiv.
Finally, we developed dominant miR156-resistant alleles rSPL3, rSPL4, and rSPL13 that accelerate wheat heading time that can be used to improve wheat adaptation to changing environments.
Additionally, We showed that DELLA proteins can interact with SPL proteins reducing their ability to induce flowering and that interactions between DELLA and both VRN1 and FUL2 can compete with the DELLA-SPL interactions, likely reducing DELLA’s ability to repress SPL3 and SPL4 activity.
Earlier heading was associated with the upregulation of miR172 and flowering-promoting genes VRN1, FUL2, and FT1 and the downregulation of flowering-repressing genes AP2L1 and VRN2.
We also characterized the interactions between the age, photoperiod, vernalization and GA pathways in pasta wheat. Plants with reduced levels of microRNA156 or higher expression of SPL3, SPL4, and SPL13 exhibited accelerated heading time, with stronger effects under suboptimal inductive conditions.
Our manuscript on the role of the SPL genes and the endogenous age pathway on wheat heading time is now available in bioRxiv!
www.biorxiv.org/cgi/content/...
Explore the spatial distribution of the 74,464 genes imputed from the single cell RNA-seq into the spatial transcriptomics at dubcovskylab.ucdavis.edu/imputed-genes.
You can visualize the spatial distribution of the 99 genes included in the spatial transcriptomics analysis at dubcovskylab.ucdavis.edu/JD99-wheat-s...
Our Genome Biology paper on wheat spike development integrating single cell and spatial transcriptomics is now published! Check out the paper here: doi.org/10.1186/s130... and enjoy the beautiful pictures (including our 44 supplementary figures)! Be sure to check out some of our tools below!
74,464 genes with imputed expression from single cell RNA-seq into spatial transcriptomics cells dubcovskylab.ucdavis.edu/imputed-genes.
We also developed two WEB tools to visualize gene expression in cells of wheat developing spikes linked in the thread below!
An update to our spatial transcriptomics study of the wheat spike is now available in bioRxiv! The updated version includes functional validation of the roles associated with the specific expression patterns of LFY in intercalary meristems, SPL14 in inflorescence meristems, and FZP in glume axillae.
🌱From Crop Science: New wheat lines combining Yr78 with other resistance genes cut stripe rust severity, offering stronger, multi-gene protection for breeders. (Chen Dang, Joshua M Hegarty, Xiaofei Zhang, Jorge Dubcovsky)
▶️ acsess.onlinelibrary.wiley.com/doi/10.1002/...
#PlantScience #PlantPathology
In this paper, we report the transfer of the stripe rust resistance gene Yr78 to durum wheat (PI 702944) and the combination of the resistance genes Yr36 and Yr78 in coupling in common wheat (PI 706442) to facilitate their simultaneous deployment in wheat breeding programs.
Our lab recently published "Durum wheat with Yr78 and common wheat with Yr78 and Yr36 in coupling show enhanced stripe rust resistance"
The federal government's $1B dollar demand from the University of California is designed to devastate public Universities and their critical mission. Our lab will #StandUpForUC to defend one of America’s greatest public university systems and support this life-saving work. ucal.us/standupforuc
Talking Biotech 467 - #Celiac safe wheat? Less immunoreactive wheat has been developed by
@UCDavisPlants using old-school mutagenesis. A scintillating talk with grad student Maria Rottersman.
@ASPB
share.transistor.fm/s/9419052e
🎙️ Just published a new episode of Talking Biotech with Dr. Kevin Folta: Old Tricks, New Wheat for Celiacs - Maria Rottersman. Have a listen:
🌱 From UC Davis: Deleting key gliadin genes boosts wheat gluten strength & cuts celiac-triggering epitopes—without harming yield. (Maria Rottersman, Jorge Dubcovsky)
▶️ www.ucdavis.edu/food/news/ta...
New work from a graduate student, Maria Rottersman, and others in the lab demonstrates that deleting the alpha-gliadins on chromosome 6D of wheat improves gluten strength and produces less celiac disease epitopes. Check it out now in Theoretical and Applied Genetics: rdcu.be/egXZ2
A high-quality genome assembly of the durum wheat landrace PI 192051. a Circular diagram showing the assembly features of PI 192051. The tracks, arranged from outermost to innermost, include: (i) chromosomes, (ii) GC content, (iii) gene density, and (iv) syntenic connections between A and B subgenomes. b Comparison of genome assembly quality (contig N50) between PI 192051and other published tetraploid (turquoise blue) and hexaploid (pink) wheat genomes. The horizontal axis represents the year, and the vertical axis represents the contig N50 size. Each circle represents one genome, with the diameter of the circle corresponding to the genome size. PI 192051 is highlighted with a red arrow. c Syntenic blocks among T. urartu (G1812 v2.0), T. monococcum (PI 306540), T. durum (PI 192051 and Svevo v1.0), T. dicoccoides (Zavitan v1.0), Ae. searsii (TE01), Ae. speltoides (TS01), and the A/B subgenomes of the bread wheat variety Chinese Spring (CS, RefSeq v2.1). Each line represents a syntenic block of 15 or more gene pairs with ≥ 80% identity.
🌱From a Nature Portfolio preprint: Cloning of Lr30 reveals it’s identical to Lr.ace-4A and encodes a unique NLR gene conferring strong rust resistance in durum #wheat, but less so in hexaploid. (Jorge Dubcovsky)
▶️ www.researchsquare.com/article/rs-6...
#PlantScience #PlantImmunity
Please read this statement supporting science from members of US National Academies of Science, Engineering, and Medicine. It’s important we stand against these egregious cuts to science.
Check out this article by a previous lab member, Iago Hale, on the impact of cuts to the USDA germplasm system. Definitely worth a read! www.nytimes.com/2025/03/22/o...
Check out our work on fine-tuning miRNA control of plant height in wheat and triticale, as covered by the folks at the plant sciences department! www.plantsciences.ucdavis.edu/news/deberna...
Plant Science Research Weekly -- Single cell analysis of wheat spike development (bioRxiv) @dubcovskylab.bsky.social (Summary by Mary Williams @PlantTeaching.bsky.social ) buff.ly/O6elukV
#PlantaePSRW
Three stages of wheat spike development with color-coded labels showing gene expression clusters. Several structures are visible clearly changing in form and gene expression pattern between the three developmental stages.
#PlantSci Research Weekly March 7 plantae.org/plant-scienc... (2/2) Single-cell analysis of wheat spikelet; Autoactivated calcium channel enhances symbiosis; Fungal pathogen hijacks phosphate signaling; Erucamide inhibits the type III secretion system; How Rhodanobacter R179 evades plant immunity
Spatial cell clusters based on the expression of 99 genes analyzed by smFISH at three stages of wheat spike development.
Expression profiles of genes differentially expressed during spikelet development.
We’re excited to share our new preprint on wheat spike development! We used spatial transcriptomics and scRNA-seq to take a closer look at the different cell types and expression domains during key developmental stages of the wheat spike. Check it out here:
www.biorxiv.org/content/10.1...