🫤 hmmm…why on earth is a supposedly immunocompetant young person getting a disseminated fungal infection. Immunity debt?😅

Case: 27yo previously well immunocompetant male presents with a MCA stroke due to cardioembolic stroke from disseminated aspergillosis leading to a mycotic cerebral aneurysm which ruptures causing death.

COVID vaccines tied to less hospital care, long COVID, and economic burden

In the UK the NHS is absolutely overwhelmed, but the government has tightened the eligibility criteria for free Covid vaccination to the point that only a small minority of the population is eligible. Offering free vaccination to everyone would be an easy win here

www.cidrap.umn.edu/covid-19/cov...

'World's first' trial of regenerative knee treatment set to begin in Japan Method uses 3D-printed tissue to repair damaged bone and cartilage

'World's first' trial of regenerative knee treatment set to begin in Japan

Method uses 3D-printed tissue to repair damaged bone and cartilage
trib.al/IwotWiG

Government advisory group urges delay of NDIS 'robo' changes The federal government has been urged by its own NDIS advisory group to delay the rollout of a controversial new way of determining support plans for participants.

Instead of submitting evidence of their disability from doctors, participants will be interviewed by an assessor, who then feeds their findings into a computer program.

That algorithm will then spit out a budget to be approved or rejected by an NDIS employee www.abc.net.au/news/2026-04...

Pancreatic cancer mRNA vaccine shows lasting results in an early trial Scientists caution that more research is needed, but nearly all of the patients who responded to the personalized vaccine are still alive six years later.

"Pancreatic cancer mRNA vaccine shows lasting results in an early trial: Scientists caution that more research is needed, but nearly all of the patients who responded to the personalized vaccine are still alive six years later."

Australian Government media release page titled “Free RSV vaccine for older Australians.” Banner includes a photo of Health Minister Mark Butler. Text states the government is introducing free RSV vaccinations for older Australians to protect against severe illness. Details show media event date and publication date: 19 April 2026. Media type: Media release. Audience: General public.

Free RSV vaccine for older Australians.

From 15 May, a $445.3 million investment will fund free Arexvy RSV vaccines for Australians aged 75+ and Aboriginal and Torres Strait Islander people aged 60+, with doses otherwise costing around $300 without NIP listing.

www.health.gov.au/ministers/th...

Original Article | APR 16, 2026 Asundexian for Secondary Stroke Prevention (OCEANIC-STROKE) Figure 1A. Cumulative Incidence of Ischemic Stroke.

In the phase 3 OCEANIC-STROKE trial involving patients with noncardioembolic ischemic stroke or high-risk TIA, asundexian added to antiplatelet therapy led to a lower risk of ischemic stroke without increasing major bleeding. Full trial results: nej.md/3O1O0Aj

Australian C19 Weekly Update - 10th April 2026

Note: Cases recorded are from PCR testing only. Actual cases are significantly higher.

Data from: nindss.health.gov.au/pbi-dashboard/

Thanks to @angiecibisdesign for the design!

1/4

#Eurostat: Zahl gesunder Lebensjahre bei Geburt ist in SCHWEDEN von 73,3 (2019) auf 66,2 Jahre in 2023 gesunken

Deutschland von 66,3 auf 62,5
EU Durchschnittlich 64,6 auf 63,1

Hat aber alles nix mit #Covid zu tun - sind nur die Nerven
Quelle inkl Daten

x.com/avslojar/sta...

Society of Interventional Radiology Annual Meeting Original Article | APR 13, 2026 | NEJM.org Endovascular Therapy for Post-Thrombotic Syndrome — A Randomized Trial (C-TRACT) Figure 2A. Severity of Post-Thrombotic Syndrome According to Venous Clinical Severity Score (VCSS).

Among patients w/ moderate or severe PTS, the addition of endovascular therapy to standard care resulted in less severe PTS and better quality of life at 6 months than standard care alone but w/ a higher risk of bleeding. Full phase 3 C-TRACT trial results: nej.md/3QsqxJ2

#SIR26TOR | @sirweb.org

I'm at LithoLink's #StoneCamp. Asplin is explaining that the first rule of stone camp is you don't talk about stone camp. I am tweeting under table. I may get kicked out.

If ASEAN had to choose between the U.S. and China, who would it pick?
trib.al/U5gOrXS

Here's the latest variant picture with a global scope, to late March.

XFG.* "Stratus" continued to dominate, but fell to 47% frequency.

NB.1.8.1 "Nimbus" grew to 29%.

BA.3.2.* "Cicada" grew to 14%.
🧵

Japanese recyclers have developed methods to extract lithium, nickel, palladium and other rare metals from disused electronic devices. This helps secure steadier supplies of metals critical to manufacturers.

Malnourished Afghan minors trapped as two wars cut off supplies Taliban-Pakistan tensions, US-Israel attacks force millions into acute food insecurity

Malnourished Afghan minors trapped as two wars cut off supplies
asia.nikkei.com/politics/international-r...

Safety review links herb in popular cold and flu supplements with life-threatening anaphylaxis

Triggering multiple sclerosis: infection with Epstein-Barr virus activates multiple pre-existing autoreactive B and T cells - Signal Transduction and Targeted Therapy Signal Transduction and Targeted Therapy - Triggering multiple sclerosis: infection with Epstein-Barr virus activates multiple pre-existing autoreactive B and T cells

LMU Munich researchers report EBV may help trigger MS by awakening pre existing immune cells that attack myelin, setting off brain inflammation and myelin loss years after infection.

www.nature.com/articles/s41...

The New England Journal of Medicine Discontinuation of Beta-Blocker Therapy after Myocardial Infarction A Research Summary based on Choi KH et al. | 10.1056/NEJMoa2601005 | Published on March 30, 2026 Visual representations of the patients in the trial and the treatments they were assigned. Read the full Research Summary at NEJM.org.

Among patients with a preserved ejection fraction at least 1 year after myocardial infarction, stopping beta-blockers was noninferior to continuing therapy with respect to major clinical outcomes. Full SMART-DECISION trial results and Research Summary: nej.md/3NsStM6

#Cardiology

MAGA Is Winning Its War Against U.S. Science When a political movement believes that ignorance is strength

MAGA Is Winning Its War Against U.S. Science

MAGA Is Winning Its War Against U.S. Science When a political movement believes that ignorance is strength

MAGA Is Winning Its War Against U.S. Science

New COVID strain circulating in Australia as it spreads across the globe

Australia: New COVID strain BA.3.2, otherwise known as “Cicada”, circulating in Australia as it spreads globally.

🔹NSW: 10,247 cases
🔹QLD: 6,378 cases
🔹VIC: 3,635 cases
🔹SA: 1,932 cases
🔹WA: 773 cases
🔹ACT: 225 cases
🔹TAS: 263 cases
🔹NT: 128 cases

A deadly bacterial disease is returning, doctors warn, as vaccination rates fall Hib once killed 1,000 children a year, permanently disabling many more. Doctors who've never seen the disease say the comeback is changing the way they practice medicine.

“The last night I was a pediatric resident, a child came in with Hib and promptly died by the next day. I didn’t work for 50 years to have everything destroyed by one man.”

-Dr. Kathryn Edwards, Vanderbilt University

This is what RFK Jr. and the anti-vaxxers have wrought.

🚨🚧🚨🚧🚨🚧🚨🚧🚨🚧🚨🚧🚨

CATA Press Release following publication of Baroness Hallett’s report:
tinyurl.com/CATA-PR-Apr-...

MAJOR WINS for CATA (and true scientists everywhere!)
Complete vindication (see thread below)

BUT

There were some major omissions (see Press Release)

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The Inquiry recognised that reporting of HCW deaths under the RIDDOR Regulations for reporting occupational disease should be better.

Sadly it didn't address the failure to report occupational infections which don’t cause deaths but leave HCWs crippled with Long-COVID.

/End

#LongCOVID is associated with increased risk of incident cardiovascular disease, particularly cardiac arrhythmias, heart failure, and coronary artery disease. Long COVID was not associated with stroke

Long COVID and risk of incident cardiovascular disease: a prospective cohort study using the Multimorbidity Integrated Registry Across Care Levels in Stockholm (MIRACLE-S) cohort Long COVID is associated with increased risk of incident cardiovascular disease, particularly cardiac arrhythmias, heart failure, and coronary artery disease. These findings underscore the need for sy...

Long COVID and risk of incident cardiovascular disease: a prospective cohort study using the Multimorbidity Integrated Registry Across Care Levels in Stockholm (MIRACLE-S) cohort - eClinicalMedicine www.thelancet.com/journals/ecl...

The IgAN Nephropathy curriculum provides a comprehensive review of the pathogenesis, treatment, and prediction of disease progression to help clinicians in their work.

Access the new curriculum, supported by Otsuka: https://bit.ly/3PirS4N

Trump says U.S. could end Iran war in two to three weeks 'We'll be leaving very soon,' president says

Trump says U.S. could end Iran war in two to three weeks
asia.nikkei.com/spotlight/iran-tensions/...

The International Society of Nephrology General Assembly is currently taking place in Yokohama during World Congress of Nephrology 2026.

Members are gathering to discuss ongoing work and next steps for the organization.

#ISNWCN #ThisIsISN