TRIM24 directs replicative stress responses to maintain ALT telomeres via chromatin signaling Kim et al. develop BLOCK-ID, an approach to capture replication stress response factors. The chromatin reader TRIM24 was identified as a critical mediator of alternative lengthening of telomeres (ALTs) through a mechanism involving histone acetylation and SUMOylation signaling that, when disrupted, results in aberrant telomere function in ALT-positive cells.

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A postdoc position is available in our lab to study ADP-ribosylation and ubiquitylation signalling! We are looking for someone with experience in structural biology and biochemistry. The application deadline is June 20th.
my.corehr.com/pls/uoxrecru...

I think this is the best first post I can think of! Hello from Pittsburgh's first snow day this winter!