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Posts by Waggoner Lab

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A novel cultivation strategy to recover NK cell cytotoxicity
www.frontiersin.org/journals/bio...

31 minutes ago 1 0 0 0
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Review @frontiersin.bsky.social Metabolic licensing at the dendritic cell–NK cells immune synapse in viral asthma exacerbations
www.frontiersin.org/journals/imm...

33 minutes ago 0 0 0 0
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Review @cp-trendsimmuno.bsky.social @nbjorkstrom.bsky.social @ki.se
Local cues, local killers: human NK cells across tissues
www.sciencedirect.com/science/arti...

34 minutes ago 0 0 0 0
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HIF-1α impairs NK cell differentiation-maturation and cytotoxicity in myelodysplastic syndrome via JAK1/STAT5/SOCS2 pathway @jimmunol.bsky.social
academic.oup.com/jimmunol/art...

36 minutes ago 0 0 0 0
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Functional segregation of HIF-1α and AhR controls NK cell responsiveness under hypoxia Multiple mechanisms operate to transform microenvironmental information into cellular adaptation, but how environmental sensors mechanistically synerg…

Functional segregation of HIF-1α and AhR controls NK cell responsiveness under hypoxia @cp-iscience.bsky.social www.sciencedirect.com/science/arti...

37 minutes ago 1 0 0 0
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Loss of Vpr-driven TRAIL-R2 expression protects HIV-infected cells from non-canonical NK cell TRAIL attack
@biorxivpreprint.bsky.social @umasschan.bsky.social
www.biorxiv.org/content/10.6...

41 minutes ago 0 0 0 0
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@biorxivpreprint.bsky.social Not so cold after all: tumor infiltrating CD8+ T cells in EBV-positive Burkitt lymphoma are quiescent, not exhausted @umasschan.bsky.social
www.biorxiv.org/content/10.6...

44 minutes ago 1 0 0 0
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@biorxivpreprint.bsky.social JAML-CXADR interaction regulates NK cell-mediated killing of tumors
www.biorxiv.org/content/10.6...

50 minutes ago 0 0 0 0
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@biorxivpreprint.bsky.social KIR*BLOOM: Accurate KIR genotyping using a new copy number-aware integrated genotype likelihood framework
www.biorxiv.org/content/10.6...

52 minutes ago 1 0 0 0
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PIM1 kinase–regulated cellular metabolism sustains differentiation and function of effector CD8+ T cells during chronic viral infection @jimmunol.bsky.social @feinberg.northwestern.edu
academic.oup.com/jimmunol/art...

59 minutes ago 1 0 0 0
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Pathophysiological roles of monocytes and macrophages in cancer - Nature Reviews Immunology Monocytes and macrophages adopt modular programmes in response to cancer cells, which can be viewed as an ‘infectious self’ challenge, and cues from the surrounding tissue environment as well as organ...

Review @natrevimmunol.nature.com @mskcancercenter.bsky.social
Pathophysiological roles of monocytes and macrophages in cancer
www.nature.com/articles/s41...

1 hour ago 1 0 0 0
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Indirect suppression of inflammasome activity contributes to the efficacy of Janus kinase 1–preferential inhibitors in colitis @natcomms.nature.com
www.nature.com/articles/s41...

1 hour ago 1 0 0 0
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Igh nuclear speckle association promotes V(D)J recombination @natcomms.nature.com
www.nature.com/articles/s41...

1 hour ago 1 0 0 0
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BLIMP1 attenuates BCR signaling and constrains the LZ to DZ transition, fine-tuning clonal competition, thereby maintaining repertoire diversity @natimmunol.nature.com @pitt-immunology.bsky.social www.nature.com/articles/s41...

1 hour ago 0 0 0 0
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A vaccine strategy to prevent the progression of pulmonary fibrosis @natimmunol.nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...

1 hour ago 1 0 0 0
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A T cell differentiation program analogous to that in chronic infections and cancer is found in lupus; however, CD8+ T cells in systemic autoimmunity retain effector function despite terminal differentiation @cp-immunity.bsky.social
www.cell.com/immunity/ful...

1 hour ago 1 0 0 0
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@cincyresearch.bsky.social @cp-iscience.bsky.social
Ambient temperature regulates CD4+ T cell tonic T cell receptor signaling and responsiveness
www.cell.com/iscience/ful...

1 hour ago 0 0 0 0
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Review @moltherapy.bsky.social
A Primer On Prime: A Prime Editing Update from Advances to First-in-Human Trial
www.cell.com/molecular-th...

1 hour ago 0 0 0 0
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LTβR acts as a master regulator controlling the development of pain chronicity by shaping a peripheral gene plasticity network that drives sensory neuronal sensitization @cp-cellreports.bsky.social @uthealthsa.bsky.social
www.cell.com/cell-reports...

1 hour ago 0 0 0 0
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Durable control of autoimmunity requires sustained stimulation of regulatory T cells @cp-cellreports.bsky.social
www.cell.com/cell-reports...

1 hour ago 2 0 0 0
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Spleen-targeted neoantigen mRNA vaccine induces ISG15+ CD8+ T cell-mediated tertiary lymphoid structure formation in hepatocellular carcinoma @cp-cellrepmed.bsky.social
www.cell.com/cell-reports...

1 hour ago 1 0 0 0
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Microbiota-derived ergothioneine counteracts antipsychotic-induced cognitive impairment @cp-cellhostmicrobe.bsky.social
www.cell.com/cell-host-mi...

1 hour ago 2 2 0 0
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An infant nasal microbial gene atlas uncovers intervention-driven microbiome shifts and salt-resistant pathogen expansion
@cp-cellhostmicrobe.bsky.social @thexavierlab.bsky.social
@broadinstitute.org
cell.com/cell-host-mi...

1 hour ago 2 1 0 0
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CRISPR-KO and CRISPRa screens in primary human CD4 T cells reveal pro- and anti-(PI16, PPID, SHISA3, ITM2A) HIV host factors @cellcellpress.bsky.social @gladstoneinst.bsky.social
@marsonlab.bsky.social www.cell.com/cell/fulltex...

1 hour ago 2 0 0 0
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Bi-Functional Anti-LAG-3-IL-2c Enhances Immune Checkpoint Inhibitor and CAR T-Cell Therapy for Cancer The effectiveness of cancer immunotherapies in solid tumors is often limited by challenges such as transient efficacy and low response rates. T-cell exhaustion is one key mechanism that impairs T-cell...

Bi-Functional Anti-LAG-3-IL-2c Enhances Immune Checkpoint Inhibitor and CAR T-Cell Therapy for Cancer
@cp-iscience.bsky.social
www.cell.com/iscience/ful...

1 hour ago 2 1 0 0
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Peripheral vaccination-induced brain-resident memory CD8+ T cells durably protect mice against intracranial malignancy @jci.org
www.jci.org/articles/vie...

3 days ago 10 2 0 0

Gene delivery of immunomodulatory cytokines to the lung preserves respiratory function during inflammatory challenge @labliston.bsky.social @sciimmunology.bsky.social
@babrahaminst.bsky.social @drntombizodwa.bsky.social
www.science.org/doi/10.1126/...

3 days ago 18 5 0 0
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The autoantigen TRIM21 assembles proinflammatory immune complexes after lytic cell death
@sciimmunology.bsky.social
@ox.ac.uk @jelenalab.bsky.social
www.science.org/doi/10.1126/...

3 days ago 1 1 0 0
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Divergent granulopoiesis at extramedullary sites safeguards antibacterial host defense @sciimmunology.bsky.social
www.science.org/doi/10.1126/...

3 days ago 3 0 0 0
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Review @jci.org
Immune signaling and function in neurodegeneration
www.jci.org/articles/vie...

3 days ago 0 0 0 0