A novel cultivation strategy to recover NK cell cytotoxicity
www.frontiersin.org/journals/bio...
Posts by Waggoner Lab
Review @frontiersin.bsky.social Metabolic licensing at the dendritic cell–NK cells immune synapse in viral asthma exacerbations
www.frontiersin.org/journals/imm...
Review @cp-trendsimmuno.bsky.social @nbjorkstrom.bsky.social @ki.se
Local cues, local killers: human NK cells across tissues
www.sciencedirect.com/science/arti...
HIF-1α impairs NK cell differentiation-maturation and cytotoxicity in myelodysplastic syndrome via JAK1/STAT5/SOCS2 pathway @jimmunol.bsky.social
academic.oup.com/jimmunol/art...
Functional segregation of HIF-1α and AhR controls NK cell responsiveness under hypoxia @cp-iscience.bsky.social www.sciencedirect.com/science/arti...
Loss of Vpr-driven TRAIL-R2 expression protects HIV-infected cells from non-canonical NK cell TRAIL attack
@biorxivpreprint.bsky.social @umasschan.bsky.social
www.biorxiv.org/content/10.6...
@biorxivpreprint.bsky.social Not so cold after all: tumor infiltrating CD8+ T cells in EBV-positive Burkitt lymphoma are quiescent, not exhausted @umasschan.bsky.social
www.biorxiv.org/content/10.6...
@biorxivpreprint.bsky.social JAML-CXADR interaction regulates NK cell-mediated killing of tumors
www.biorxiv.org/content/10.6...
@biorxivpreprint.bsky.social KIR*BLOOM: Accurate KIR genotyping using a new copy number-aware integrated genotype likelihood framework
www.biorxiv.org/content/10.6...
PIM1 kinase–regulated cellular metabolism sustains differentiation and function of effector CD8+ T cells during chronic viral infection @jimmunol.bsky.social @feinberg.northwestern.edu
academic.oup.com/jimmunol/art...
Review @natrevimmunol.nature.com @mskcancercenter.bsky.social
Pathophysiological roles of monocytes and macrophages in cancer
www.nature.com/articles/s41...
Indirect suppression of inflammasome activity contributes to the efficacy of Janus kinase 1–preferential inhibitors in colitis @natcomms.nature.com
www.nature.com/articles/s41...
Igh nuclear speckle association promotes V(D)J recombination @natcomms.nature.com
www.nature.com/articles/s41...
BLIMP1 attenuates BCR signaling and constrains the LZ to DZ transition, fine-tuning clonal competition, thereby maintaining repertoire diversity @natimmunol.nature.com @pitt-immunology.bsky.social www.nature.com/articles/s41...
A vaccine strategy to prevent the progression of pulmonary fibrosis @natimmunol.nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
A T cell differentiation program analogous to that in chronic infections and cancer is found in lupus; however, CD8+ T cells in systemic autoimmunity retain effector function despite terminal differentiation @cp-immunity.bsky.social
www.cell.com/immunity/ful...
@cincyresearch.bsky.social @cp-iscience.bsky.social
Ambient temperature regulates CD4+ T cell tonic T cell receptor signaling and responsiveness
www.cell.com/iscience/ful...
Review @moltherapy.bsky.social
A Primer On Prime: A Prime Editing Update from Advances to First-in-Human Trial
www.cell.com/molecular-th...
LTβR acts as a master regulator controlling the development of pain chronicity by shaping a peripheral gene plasticity network that drives sensory neuronal sensitization @cp-cellreports.bsky.social @uthealthsa.bsky.social
www.cell.com/cell-reports...
Durable control of autoimmunity requires sustained stimulation of regulatory T cells @cp-cellreports.bsky.social
www.cell.com/cell-reports...
Spleen-targeted neoantigen mRNA vaccine induces ISG15+ CD8+ T cell-mediated tertiary lymphoid structure formation in hepatocellular carcinoma @cp-cellrepmed.bsky.social
www.cell.com/cell-reports...
Microbiota-derived ergothioneine counteracts antipsychotic-induced cognitive impairment @cp-cellhostmicrobe.bsky.social
www.cell.com/cell-host-mi...
An infant nasal microbial gene atlas uncovers intervention-driven microbiome shifts and salt-resistant pathogen expansion
@cp-cellhostmicrobe.bsky.social @thexavierlab.bsky.social
@broadinstitute.org
cell.com/cell-host-mi...
CRISPR-KO and CRISPRa screens in primary human CD4 T cells reveal pro- and anti-(PI16, PPID, SHISA3, ITM2A) HIV host factors @cellcellpress.bsky.social @gladstoneinst.bsky.social
@marsonlab.bsky.social www.cell.com/cell/fulltex...
Bi-Functional Anti-LAG-3-IL-2c Enhances Immune Checkpoint Inhibitor and CAR T-Cell Therapy for Cancer
@cp-iscience.bsky.social
www.cell.com/iscience/ful...
Peripheral vaccination-induced brain-resident memory CD8+ T cells durably protect mice against intracranial malignancy @jci.org
www.jci.org/articles/vie...
Gene delivery of immunomodulatory cytokines to the lung preserves respiratory function during inflammatory challenge @labliston.bsky.social @sciimmunology.bsky.social
@babrahaminst.bsky.social @drntombizodwa.bsky.social
www.science.org/doi/10.1126/...
The autoantigen TRIM21 assembles proinflammatory immune complexes after lytic cell death
@sciimmunology.bsky.social
@ox.ac.uk @jelenalab.bsky.social
www.science.org/doi/10.1126/...
Divergent granulopoiesis at extramedullary sites safeguards antibacterial host defense @sciimmunology.bsky.social
www.science.org/doi/10.1126/...
Review @jci.org
Immune signaling and function in neurodegeneration
www.jci.org/articles/vie...