Even the flatworms are getting stupider over time…must be global warming.

🐔 p < 0.05, 🦆 p < 0.01, 🦉 p < 0.001, 🦅 p < 0.0001, 🦤= n.s.

Significant differences are indicated with 🐦‍⬛

Where U.S. science has been hit hardest after Trump’s first year The Trump administration has slashed the number of grants from the National Institutes of Health, with far fewer focused on women, cancer and mental health.

Those of us doing research related to women’s health have been hit particularly hard by the govt’s sabotage of the NIH. I spoke to WaPo for this piece, as painful as it was to discuss the reality my lab is facing. www.washingtonpost.com/science/2026...

Well this is an instant classic and fabulous demonstration of why implementation details are so important.

Stimulate when white rabbit peaks.

7-layer cortex.

Sam Altman May Control Our Future—Can He Be Trusted? New interviews and closely guarded documents shed light on the persistent doubts about the head of OpenAI.

“Capture the light cone of all future value in the universe" is an objectively hilarious quote… but is also kinda how we think primates resolve the explore-exploit dilemma.

www.newyorker.com/magazine/202...

Jeremy we’re not that desperate for funding…yet

Risk reshapes amygdala representation of choice Piantadosi et al. show mice flexibly adjust choices between reward options based on the punishment potential in a BLA-dependent manner. They find that BLA neuronal representation of punishment reactiv...

www.cell.com/neuron/fullt...

A monkey model of retinal ganglion cell degeneration Optic neuropathies due to heritable diseases are a common cause of blindness in humans, but limited therapies currently exist for the vision loss that occurs from them. One such condition is autosomal...

link.growkudos.com/1f6gc1c9x4w
#visionscience

A play in two parts:

Hang in there. Many of us started with ND.

Also, Katz is such a crapshoot based on whether reviewers really embrace ethos of the mechanism or not. Hopefully summary statements are helpful.

Ok as far as logos go this is impressive

There is a lot of amazing free bread in DC. I love DC because of it.

Le Diplomate in DC, for sure. I mean if you eat all the free bread and then pay to eat more bread you know it’s good.

Also literally any bread product served to me at Dabney in DC that is accompanied by their sorghum butter.

Third is the free bread at Red Hen in DC.

And this is me: “The first type of American: people who joyride the day’s updrafts like marvelous, glossy crows. They easily recall the locations of treats encountered over their lifetime. They answer this question Glock-shot fast, as if they have been waiting to be asked it. They are happy.”

Well I know what I am reading tonight.

This paper changed my life: Erin Calipari ponders the nuances of rewarding and aversive stimuli A 1960s study by Kelleher and Morse found that lever pressing in squirrel monkeys depended not on whether they received a reward or shock, but on the rules of the task. This taught Calipari to think…

In our latest edition of “This paper changed my life,” Erin Calipari shares how a 1960s paper taught her to think deeply about factors that influence how behavior is generated and maintained. #neuroskyence

www.thetransmitter.org/this-paper-c...

I love it when I see a preprint that really shakes up my view of how the brain works.

And fellowship review isn’t necessarily all about the science so much as the training plan, and people that are regular reviewers on fellowship panels have relevant expertise in critiquing those across broad categories.

Seconding what Jan said. SRO will do their job and get relevant expertise onto the panel, but fellowships panels are always a hodgepodge and the titles reflect that.

If you are an early career NHP researcher (postdoc or asstiant professor) and interested in attending #ACNP2027 please apply.

I’ve also rolled off the E&T Committee that reviews these awards and am now an “ambassador” so if anyone wants some advice about applying for travel awards, reach out.

I wish I could tell all the young eager people who write to me about wanting to do research, or the new novel exciting theory they have developed, that if your email (or worse, theory) was very obviously generated by chatGPT it will be very hard for anybody to take you seriously.

Getting an NIH grant, when money is released, is getting exponentially harder. You basically will need all three reviewers to score your grant as perfect to have a shot at funding.

You prefer the term junto?

a close up of a man 's face with the words inconceivable written on it . ALT: a close up of a man 's face with the words inconceivable written on it .

But try convincing 20 other academics, who you’ve never met before, via Zoom, to all agree a grant should receive 1s & 2s.

Now make 10 of them drosophila or worm researchers. Make another 5 hippocampus researchers. Out of those 15, 8 believe mice have a prefrontal cortex.

Like I said…doomed.

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