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Posts by COSYNE

Morphoelectric properties of inhibitory neurons shift gradually and regardless of cell type along the depth of the cerebral cortex How can we understand the enormous diversity of the GABAergic inhibitory neurons in the cerebral cortex? To address this question, we quantify the electrophysiological and morphological properties of inhibitory neurons across the depth of an entire cortical column in the rat barrel cortex. We find properties that shift gradually with the cortical depth of the cell bodies across all inhibitory neurons, regardless of their cell types. By isolating morphoelectric variations from their shifts along the cortical depth, we find that the same simple relationships between morphoelectric properties distinguish between the four main molecular cell types of inhibitory neurons at any cortical depth, and in both the rat barrel cortex and mouse primary visual cortex. We provide converging evidence from dense electron-microscopic reconstructions of inhibitory neurons in the mouse visual cortex, and observe comparable depth-dependent shifts in additional datasets from the mouse primary motor cortex and the middle temporal gyrus of the human cortex. Our findings indicate that two different sources of morphoelectric variations can account for the diversity of cortical inhibitory neurons. The first source is molecular cell type-specific, but cortical depth-independent. The second source is cortical depth-dependent, but affects inhibitory neurons similarly across all cell types. We propose that intrinsic developmental specification vs. extrinsic environmental modulation leads to such a decoupling of inhibitory type-specific properties from gradual shifts of these properties with cortical depth. ### Competing Interest Statement The authors have declared no competing interest. European Research Council, https://ror.org/0472cxd90, 633428 Deutsche Forschungsgemeinschaft, SFB 1089, SPP 2041, Fe472/2-1 Bundesministerium für Bildung und Forschung, 01GQ1002, 01IS18052 Neuroscience Network North Rhine-Westphalia, iBehave National Institutes of Health, https://ror.org/01cwqze88, R24MH117295 The Kavli Foundation, NeuroData Discovery Award

Check our recent preprint (with Yáñez, Messore,Qi,Meyer, Feldmeyer, Bert Sakmann, Oberlaender)
Presented @cosynemeeting.bsky.social 2025
#cosyne2026
Morphoelectric properties of inhibitory neurons shift gradually and regardless of cell type along the cortical depth share.google/GYGGquVAHyow...

1 month ago 6 2 0 0
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Cosyne 2026 - Tutorial: Open Neurophysiology Data Tutorial: NWB, DANDI, and IBL YouTube video by Cosyne Talks

We gave a tutorial on @nwb.org and DANDI at @cosynemeeting.bsky.social this year. If you couldn't make it (or want a refresher), the full recording is up on YouTube. Covers everything from data standardization to finding and reusing public neurophysiology datasets on DANDI.

1 month ago 26 8 0 0

Xiaoqin Wang will be kicking off Session 6: Sensory Processing and Perception, with an enthralling comparative analysis between humans and a highly social non-human primate species, the common marmoset.

See you all at #COSYNE2026 at 8:45!

1 month ago 8 1 0 0

Only at #COSYNE2026 do we FINALLY get an answer to the age old question "Can a worm brain control a fly body?"

@bingbrunton.bsky.social thank you for answering this! You don't know how long this has been on my mind.

1 month ago 6 0 2 0

Always a captivating experience getting to listen to @bingbrunton.bsky.social share some of the amazing work being done in the Drosophila connectome 🪰 #COSYNE2026

We don't have access to Elliott's video game but if you were intrigued by her talk, check this out

www.biorxiv.org/content/10.1...

1 month ago 12 0 1 0

We're looking forward to seeing you all tonight at the @simonsfoundation.org social!

Happening at #COSYNE2026 at 20:00.

1 month ago 5 0 0 0

Joe Paton is kicking off Session 4: Decision-making and neural networks with a riveting talk on time, control, and the nervous system.

Happening right now at #COSYNE2026

1 month ago 8 0 0 0
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Instagram Create an account or log in to Instagram - Share what you're into with the people who get you.

Check out these shots captured at last nights #COSYNE2026 welcome reception!

www.instagram.com/p/DV01yNhAiq...

1 month ago 4 1 0 0
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Cosyne 2026 -  Session 1: Opening Remarks
Cosyne 2026 - Session 1: Opening Remarks YouTube video by Cosyne Talks

Fabulous keynote session at @cosynemeeting.bsky.social.

@neurokim.bsky.social and I kicked off the meeting and introduced Chris Olah.

m.youtube.com/watch?v=koGy...

1 month ago 31 9 2 3

Day 1 of #COSYNE2026 underway!

Attend session 1 for Chris Olah’s keynote lecture, and don’t miss out on the 1st poster session later this evening!

1 month ago 10 1 0 1
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Instagram Create an account or log in to Instagram - Share what you're into with the people who get you.

Follow us on instagram for live updates of what’s going on at COSYNE 2026 www.instagram.com/cosynemeetin...

1 month ago 4 2 0 0

Early rate ends this Friday,2/6 at 11:59 p.m. EST!!!

Rates go up by €100 from the 7th.

2 months ago 3 1 0 0
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Registration Deadline: Sunday, January 18 at 5:00 PM (London time). Notification: We will notify applicants of the outcome by the end of January.

We're excited for the Pre-COSYNE 2026 Brainhack! March 10–11 in Lisbon 🇵🇹

We'll be using CON²PHYS: same dataset, same questions, many truths?

🔹2 days
🔹team-based
🔹real ephys data
🔹open tools
🔹mini-presentations
🔹all skill levels

Apply now! 👇👇👇
pre-cosyne-brainhack.github.io/hackathon202...

3 months ago 7 3 0 0
Hotels (Lisbon) — COSYNE

Start reserving your rooms for #Cosyne2026!!
🏡🧠🏡🧠🏡🧠🏡

www.cosyne.org/hotels-lisbon

6 months ago 3 0 0 0
Abstract Submission — COSYNE Submit your COSYNE 2026 abstract; double‑blind, 2-page PDF. Opens Sept 5, 2025. Deadline and guidelines inside.

#Cosyne2026 deadline is just around the corner:

🧠📜 **16 October 2025! 📜🧠

See below for more on key dates and abstract submission:
www.cosyne.org/abstracts-su...

6 months ago 10 4 1 0
Travel Grants — COSYNE Apply for COSYNE 2026 Travel Grants to support your participation in Lisbon and Cascais, Portugal. Grants are available for students, postdocs, and PIs, including programs for Childcare, Presenters, N...

Undergrads can now apply for #Cosyne2026 travel grants!! 🧠🧠🧠

www.cosyne.org/travel-grants

6 months ago 3 0 0 0
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#Cosyne2026 is now open for business!

Show us what you got both for the main meeting & workshop proposals 🧠🥳🧠🥳🧠

7 months ago 45 21 0 1

Workshops Day 1! 🤩🧠🤩🧠🤩🧠🤩
Which one are you at? #Cosyne2025

1 year ago 1 0 0 0

Last day of #Cosyne2025 before heading to the workshops! 🧠🗻🤓

Hope you enjoyed:
Neuroethology
From structure to function
Sensorimotor transformations

1 year ago 0 0 0 0

Today is #Cosyne2025 Day 2, and we're making our way through:
Circuit formation
Learning and plasticity
Systemic control of behavior
Dynamic cognitive computations
🧠🤓🧠🤓🧠

1 year ago 2 0 0 0

Day 1 of #Coysne2025 underway!

Make sure to attend Session 1 & the 1st poster session later this evening!!

1 year ago 4 0 0 0

Looking forward to seeing you all in Montreal this week 🧠🧠🧠
Use #cosyne2025 so we can 👀 what you're up to!!

1 year ago 9 2 0 2
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Cosyne 2025 undergraduate mentor applications The Cosyne Undergraduate Travel Grant, is a program that brings ~12 undergraduates from across the world to Cosyne. As part of the program, we aim to pair the students with a “conference mentor”, a P...

Recruiting phd/postdocs to mentor Undergrad Awardees!!

This program brings UGs from across the 🌎 considering a career in neuro research

Duties: meet students on 1st day, take them to a poster session, help them feel welcome.

Apply: (very short!) form
forms.gle/9hCniCA29ky5...

1 year ago 16 13 0 2
Workshop Title

📣 Excited to announce our workshop "Agent-Based Models in Neuroscience: Complex Planning, Embodiment, and Beyond" at the upcoming @cosynemeeting.bsky.social #CoSyNe2025! 🧠🤖 🪱🪰🐟🐝🐭💪

Schedule: neuro-agent-models.github.io
🗓️ Join us in Mont-Tremblant, Canada, on March 31!

1 year ago 44 12 2 4
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COSYNE Join us for Computational and Systems Neuroscience (COSYNE) 2025 in Montreal and Mont Tremblant, QC, Canada. This annual meeting provides an inclusive forum for the exchange of empirical and theoretic...

Interest in natural, extended, sequential behavior is rising: super happy to be invited to the @cosynemeeting.bsky.social 2025 workshop on 'Navigation under uncertainty' March 31, Mont Tremblant organized by @jdrugowitsch.bsky.social and Mate Lengyel
www.cosyne.org

1 year ago 9 2 1 0

Please join us at our @cosynemeeting.bsky.social 2025 Workshop on Navigation under Uncertainty, organized by Máté Lengyel (Cambridge & CEU) and myself, and taking place on March 31 in the Fairmont Tremblant, Mont-Tremblant, Canada. #neuroskyence 🧠

1 year ago 15 5 1 1
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Cosyne 2025 Undergraduate Travel Grant Program

The Undergrad Travel Grant Program (deadline: Dec 6th) provides an opportunity for undergrads to learn more about comp systems neuro. It’s especially suited for students considering neuro graduate study!

Apply here:
docs.google.com/forms/d/e/1F...

More info:
www.cosyne.org/travel-grants

1 year ago 32 19 0 2