Aging drives a program of DNA methylation decay in plant organs Plants display a wide range of life spans and aging rates. Although dynamic changes to DNA methylation are a hallmark of aging in mammals, it is unclear whether similar molecular signatures reflect ra...

Absolutely delighted that our paper on epigenetic dynamics during plant aging is out today in Science!
www.science.org/doi/10.1126/...

Cryo-EM reveals open and closed Asgard chromatin assemblies Ranawat et al. show the cryo-EM structures of Asgard archaeal chromatin assemblies, revealing that the histone HHoB assembles into both compact closed and extended open hypernucleosomes. The closed co...

Really cool work by the @dodonova-sveta.bsky.social lab @embl.org www.cell.com/molecular-ce... #archea #evochromo

New Article: "Microrchidia ATPases and DNA 6mA demethylase ALKBH1 act antagonistically on PRC2 to control chromatin structure and stress tolerance" rdcu.be/eBbLK

MORCs stabilize PRC2 preferentially at bivalent domains to maintain high levels of H3 K27 trimethylation...

Transcriptional dynamics during karyogamy in rice zygotes Upon fertilization, male and female nuclei fuse to form the zygotic nucleus in angiosperms. Karyogamy is considered to be essential for proper embryogenesis; however, the transcriptional dynamics duri...

RNA-seq analysis of rice zygotes from literal single cells (a single egg, sperm, and zygote was used to make RNA-seq librarires). #PlantSciences

From: journals.biologists.com/dev/article/...

awesome!!!

High-throughput capture of transcription factor-driven epigenome dynamics using PHILO ChIP-seq Abstract. Assessing the dynamics of chromatin features and transcription factor (TF) binding at scale remains a significant challenge in plants. Here, we p

High-throughput capture of transcription factor-driven epigenome dynamics using PHILO ChIP-seq academic.oup.com/nar/advance-...

From Mark Zander lab!

Very nice microscopy showing the development of rice female gametophyte from 1 nucleus stage to fully developed stage.

Sequence logo of female-specific RdDM associated Element (FRE): GGGGGC----GCCCCC.

"the Female-specific RdDM-associated Element (FRE), which guides methylation to these loci. [...] the female-preferentially expressed protein OsCLSY3 directly interacts with FRE to regulate mCHH specifically in female reproductive tissues" #PlantScience

From: www.biorxiv.org/content/10.1...