For those writing code with agents, this *excellent* article by Timo Bingmann (who wrote COBS, for kmer geeks) is super interesting on how one can conceptualise it in terms of dependencies, and how it affects development. V fun analogies (QWERTY, cooking, money)
panthema.net/2026/0318-Vi...
The last five months with Claude Code have completely changed how we work.
matsen.group/agentic.html details:
• How agents work (& why it matters)
• Git Flow with agents
• Using agents for science
• The human-agent interface
Questions? What has your experience been?
So glad this is finally out. The method has been instrumental in allowing us to compress the AllTheBacteria data - ~2 million bacterial genomes shrink from 3Terabytes (gzipped) to 100Gb using phylogenetic compression. Great work by @brinda.eu
Now we just need an LLM to win the the literature prize #nobelprize
Pleased to announce I'm joining Cohort 7 of the Carbon13 venture builder, aiming to develop climate tech solutions with the potential to significantly reduce and prevent carbon emissions. www.linkedin.com/posts/coxton...
BWT construction and search at the terabase scale https://arxiv.org/abs/2409.00613 🧬🖥️ https://github.com/lh3/ropebwt3
crosswordgenius.com from www.unlikely.ai solves and explains cryptic clues using AI. When I give up on a clue and Google it I usually get sent there!
Great to see the study I worked on at Illumina's AI lab make it into Nature! www.nature.com/articles/s41... A lot of hard work by the lead authors, really pleased this has paid off. 🧬 🖥️
.@jnalanko.bsky.social and co. led groundbreaking work recently in terms of defining the SBWT & subset rank & select, and developing data structures for these. This new preprint provides reductions to standard rank & select, claiming similar space and 5-7x faster query arxiv.org/abs/2310.19702 🤯🧬🖥️