Desmond Morris passed away yesterday. He was one of the last living links to classical ethology. While most famous for his book "The Naked Ape" (I wasn't a fan), his work in bird behavior was foundational for both ethology and the behavioral sciences broadly. www.bbc.com/news/article...
Posts by Leo Castanedo
Someone in the Arabidopsis/clock community seems to deeply dislike my work on research culture. Just want to say: whoever you are, please write & debate me directly instead of cowering behind anonymous grant reviews that threaten my students’ work. (2nd year in a row)
That time of year again! If you'd like an example of job apps in academia or industry, here's a good resource. If you got a job in industry or academia in the last few years, please consider adding yours! github.com/RILAB/statem...
Feels like this paper on protein-templated DNA synthesis by a natural enzyme warrants some comment.
So here's a 🧵. /1
www.science.org/doi/10.1126/...
I am so excited to share our new findings with you! We provide the structural evidence for a direct protein-to-DNA information pathway, showing how a bacterial enzyme 'reads' its own structure to 'write' DNA. www.science.org/doi/10.1126/...
Very proud to share our new paper led by Mathias Brands from my team at @UniCologne! With Markus Pauly team @HHU. Host-adapted enzymatic deconstruction of acetylated xylan limits immune activation and facilitates mutualistic colonization of monocot roots: Molecular Plant www.cell.com/molecular-pl...
Siri, what's the Matthew Effect?
Are you planning on attending ICAR2026 in Singapore in June? Do you have any cool bioinformatics tools or analyses that you'd like to share with the community? We're still looking for a few speakers in our Arabidopsis Bioinformatics session - let me know by the end of April if possible via DM!
Thrilled to share our paper now out in Nature Plants 🎉
We developed a genome-host association (GHA) approach to study pathogen adaptation directly from field metadata by using the originating host cultivar as phenotype.
www.nature.com/articles/s41...
New pre-print from the lab! We show that the subtilase SBT12a is essential for symbiosome stabilization in Medicago. Using HUNTER proteomics, we even got some of its substrates. Have a look.
www.biorxiv.org/content/10.6...
This essay captures what AI for science debates often fail to recognize:
That in many academic fields, people creation is the main goal. That the supervision IS the science. That the real threat is "a slow, comfortable drift toward not understanding what you're doing"
ergosphere.blog/posts/the-ma...
Resequencing hundreds or thousands of individuals from the same species has become routine... but processing all those genomes efficiently? Still a headache!
Here's my solution that used to be lab-internal but that I am happy to share:
crolllab.github.io/genomepanel_...
Tens of thousands of papers published in 2025 contain fake/hallucinated citations, an analysis by Nature and Grounded AI suggests
By @miryamnaddaf.bsky.social and Beth Quill | @nature.com
www.nature.com/articles/d41...
Really proud of this work led by Ruben Eichfeld! We show how a CBM domain gain/loss can rewire fungal chitinases, turning them from antifungal enzymes into immune-suppressing effectors that support plant symbiosis.
www.nature.com/articles/s41...
Ever wondered how the #cuticle, a hallmark of land plants, was established?
In our latest study, we show that the CUTIN SYNTHASE enzyme family was a key driver of this evolutionary innovation. #plantscience
▶️ www.biorxiv.org/content/10.6...
A thread 🧵 [1/8]
Our new experimental evolution study across 30+ locations using the plant Arabidopsis thaliana —— we direct "see" adaptation and extinction to different climates at the genetic as it happens!
Read it in Science
dx.doi.org/10.1126/scie...
@ucberkeleyofficial.bsky.social
@hhmi-science.bsky.social
The first publication from the Dallaire and Kameoka labs is out! A forward-looking review on the status of mycorrhiza research in 2026, with emphasis on AM fungi doi.org/10.1111/nph.... @newphyt.bsky.social @ulaval.ca 🇨🇦
Madness. A bacterium with a 10kb genome, lost replication initiation, translation.., relies on symbiotic host.
www.nature.com/articles/s41...
⚠️⚠️
@jacquet-chris.bsky.social and I are organizing the 2nd "non seed plant" French meeting.
As for the one in 2025, the goal is to better structure our emerging community across French institutes.
It will take place in Toulouse, June 24th-25th.
Registration 🔽
nonseedplants26.sciencesconf.org
🥳 Happy that our manuscript, first published on @biorxivpreprint.bsky.social has been accepted for publication in "Microbiome" and will be part of a collection on "Harnessing plant microbiomes to improve performance and mechanistic understanding" link.springer.com/article/10.1...
🎉 Last week @antonkraege.bsky.social brilliantly defended his PhD thesis @unicologne.bsky.social entitled "Functional and Evolutionary Characterisation of Antimicrobial Effectors Secreted by Verticillium dahliae to Shape Host Microbiota" #proudPI #PhDone
1/11 🔥 New preprint alert 🔥
We wanted to know what plants in the wild really care about. So we asked them 🎤.
Here is what we learned: “Biotic-response networks are an important organizer of the transcriptome in wild Arabidopsis thaliana populations”
www.biorxiv.org/content/10.6...
Phylogeny of the 284 species of plants included in Conservatory data set. Conservatory uncovered ~2.3 million conserved non-coding DNA sequences across 284 plant species from 72 families including eudicots, monocots, gymnosperms, and algae. Illustrations by Professor Madelaine Bartlett.
Hiding in plain sight! 2.3M conserved non-coding sequences traced back 300M years across 284 plant species
Ground-breaking study out in First Release @science.org from labs of @madelaineb.bsky.social, @idane.bsky.social & Zach Lippman
▶️ doi.org/10.1126/scie...
▶️ www.slcu.cam.ac.uk/news/hiding-...
Just discovered this wonderful adaptation of our maize moving map (figshare.com/articles/fig...) by @andikur.bsky.social .
Thrilled to see this published! 😄
Our dispatch examines potential additional fungal symbionts in lichen partnerships and the key challenges in unraveling their biology.
Thanks for involving me in this @talbotlabtsl.bsky.social
@currentbiology.bsky.social
www.sciencedirect.com/science/arti...
Please check the latest from our lab! Root-fungus senses host nutrient status, determining its infection strategies!