One cool thing about the United States is that there are more people whose job is to deny healthcare coverage without having any medical background than there are people to provide healthcare coverage and they’ve somehow convinced people that the doctors are where the monetary waste is happening
It was an honor to present alongside these two esteemed physician-scientists who have pushed the frontiers of transplantation and cell therapy for patients with autoimmune disorders. #Tandem25
www.tandemmeetingsnews.com/experts-trac...
The cover image portrays a human composed of proteins who is examining their health status (represented by the ECG monitoring interface) with the assistance of artificial intelligence (represented by the chip and binary codes).
Something you don't see every day!
Digitizing the human proteome in >53,000 individuals with 15-year follow-up and, with machine learning, unraveling nearly 500 disease-causing proteins
www.cell.com/cell/fulltex...
open-access
Happy Holidays！💐
Credit to: Dario Brunetti
If you want to understand why healthcare pricing is horrific, the first thing to know is that our system puts 100% of the credit risk for deductibles, copays and co-insurance on hospitals and doctors. That's insane.
We have turned them into Sub Prime Lenders 🧵
Happy holidays from the Duke Rheum crew ❄️ ⛄️ 🎄 @mithurheum.bsky.social
There is a human tissue that builds itself up and breaks itself down every 28 days (on average) using non-scarring wound healing and instead of studying that and learning everything we can about it we think it's gross and look for other less relevant models to understand wound healing.
The MITIGATE trial of inebilizumab (aCD19 mAb) for IgG4-RD should get us thinking about which rheumatologic diseases do/don’t warrant deep B cell depletion (i.e. CAR Ts)
⬇️ flares
⬆️ GC-free remission (note rapid steroid taper in placebo group)
⬆️ infections & cytopenias
www.nejm.org/doi/full/10....
🆕 #ACR24 | Updated Guidelines for Lupus Nephritis Treatment & Management 🫘
Highlights 🔶
• Critical role of renal biopsy
• Differences for treatment by LN Class
• Adjunctive Rx w/ HCQ & RAASi
• GC pulse ⇢ *moderate/low* dose PDN
#Lupus #NephSky #RheumSky #Rheumatology #MedSky
It was a wonderful #ACR24 and I am truly honored to have received the Distinguished Fellow Award from the American College of Rheumatology this year
First-of-its kind evidence in severe dSSc demonstrates that CD19 CAR T may both stabilize/improve:
🔶 Fibrotic organ dysfunction
🔶 Vascular dysfunction (as marked by ⬇️ in RP severity and digital ulcerations)
🔶 Grip strength, contractures, and hand function
www.thelancet.com/journals/lan...
Thank you Mithu! Congrats to all the awardees!
Hi! Would love to be added to this list. Thanks!