Efficient in vivo mammalian neuron editing using peptide-mediated CRISPR enzyme delivery CRISPR-mediated genome editing of the central nervous system (CNS) has the potential to revolutionize the treatment of neurological disorders, including neurodegenerative disorders such as Huntington’...

Non-viral delivery of CRISPR components to the brain using peptide-enabled ribonucleoproteins

www.biorxiv.org/content/10.1...

Honored that this work represents my first "first-author" preprint of my PhD journey at
@berkeleymcb.bsky.social. Grateful for the incredible mentorship and collaborations. Neuro-PERC was a true multi-institution effort. Read the thread for the details!

Huge credit to @bmanohar.bsky.social for leading this collaborative effort, based at @innovativegenomics.bsky.social & @berkeleymcb.bsky.social, with major contributions from OSU's Krys Bankiewicz & Russ Lonser, as well as crucial support from NIH's SCGE consortium @scge.bsky.social

Efficient in vivo mammalian neuron editing using peptide-mediated CRISPR enzyme delivery www.biorxiv.org/content/10.1101/2025.11....

Sweater weather ☃️❄️

A puzzling, 3.4-million-year-old fossil foot belonged to a contemporary of the famed Lucy Identity of the toe bones and other fossils could shake up the human family tree

Newly discovered fossils tie this foot to a primitive human relative known as Australopithecus deyiremeda, an enigmatic contemporary of A. afarensis, whose species included the famed Lucy skeleton. https://scim.ag/4414MEj

For the second year in a row, IGI had a booth at #NDiSTEM, the annual conference from SACNAS! More than a hundred students stopped by to learn about IGI and opportunities at the University of California.