The what?

Whenever there’s a hopeless case, I’m the designated collaborator.
One day I will write a book about all the failed experiments (lost causes) I had to analyze.

Why we won’t be funding open access publishing any more - Cancer Research UK - Cancer News The open access movement was bold and promising, but ultimately disappointing. Now is the time to stop and call for a new way to make publishing work…

'Despite (...) attempts to limit the emphasis of the ‘publish-or-perish’ mindset, it will take time for the culture to change. As such, journal publishers still yield a lot of power – & they make a lot of money from that power. Some of the big publishing houses have profit margins approaching 40%'

I saw Suno failing in generating a much simpler track in 3/4…

Social media platforms are doomed anyway, algorithm or not, disengagement is unavoidable given enough time, as people grow and interests change. IMHO.

Congrats!!

Yep…

Yet the purpose seems noble, right? I mean, the AI slop thing…

2-panel SMBC comic update. A woman is writing on paper, sitting at a table with a knitting ball and a spool placed in front of her. A man walks by, holding an open laptop. The women says "I wish I could make a living on crafting. People should appreciate the human touch" to which the man replies, smugly "learn to code." The second panel starts with a narrative box saying "later, when all cognitive tasks have been automated." The man is flabbergasted, saying "people only want to pay workers for the human touch." The woman, now seated on a comfortable chair, holding a knitting ball, wearing sunglasses, responds "learn to knit artisanal socks biiiiiiiitch!"

The alternative was artisanal soap biiiiiitch.

COMIC ◆ www.smbc-comics.com/comic/learn-2
PATREON ◆ www.patreon.com/ZachWeinersm...
STORE ◆ smbc-store.myshopify.com

I just knew that Apple is supporting a project for CUDA bindings on Silicon

I wish I had resources to port it to Metal so that I can run on my phone.
Also, that would make sense of all these Mac laptops so popular among scientists.

“Ballmer was right” hurts.

Is it CUDA accelerated? NVIDIA specific?

4-panel SMBC comic update. Two women are talking as they walk down the street. The first woman, dressed in yellow, asks which modern democracy is the most like Athenians. The second woman - a bespectacled redhead, answers without hesitation that it is America. She continues to explain that some countries are as intellectually vibrant as the United States, and some countries are just as violent as the United States. She concludes that only one modern nation could both produce and execute Socrates. The woman in yellow responds that it's not *exactly* the same, as Athens didn't let women vote, prompting the bespectacled woman to say "we'll get there! Don't give up!"

On the last Socrates joke, like a dozen people told me I should've called his nutritional supplements Himlock, and it just kills me that I didn't.

COMIC ◆ www.smbc-comics.com/comic/athenian
PATREON ◆ www.patreon.com/ZachWeinersm...
STORE ◆ smbc-store.myshopify.com

A bit frustrating when a PI presents data and results but doesn’t go into details because “I’m not a bioinformatician”.
You may not be able to do the same calculations, but I expect you to be able to understand and present data.

The 978 genes in L1000 assay can be used to infer the expression of many other genes, and yet don’t make a commercial panel in any assay (that I’m aware of). Why?

Great work!

You can call it orthogonal

Actually that’s a true request I heard 😖

It’s weirder when NGS is used to validate qRT-PCR

The "publish or perish" culture must perish. Scientists need time to think.

We just published our Slow Science Manifesto, where we argue that huge changes are needed in the way we fund, publish, and evaluate science.

Read more and sign here: www.slow-science.com

I see now in discussion. I couldn’t read the paper before bioRxiv rendered it in HTML 😅

Next are hypestgraphs

You forgot the 5th point: the prefix “hyper” makes things much more interesting 😅

Yep, we do that kind of blunders

Great! But what was missing in inmoose?

inmoose.readthedocs.io/en/stable/

How long does it take to update profile data?

Every time I need to test an R package I spend hours compiling, resolving dependencies, fix inconsistencies.
I used to work with FreeBSD and Gentoo Linux, I swear I never spent so much time in compiling and complaining like with R

Same

Exactly!