The Orange Cat Brain Atlas is here. 🧠🐈
Today, we published the first comprehensive cellular map of the orange cat brain. The new atlas reveals a single, specialized neuron responsible for behaviors like staring at walls, knocking objects off tables, and the 3am "zoomies."
I watched Project Hail Mary with some friends and we all loved the movie, but all the science folks lost it over a 2s scene of an unbalanced centrifuge. That's to show the shared trauma we have for experiencing this equip going at thousands rpm while wobbling in place
We got to give credit to Coldplay, they were composing AI music before it was a thing
Obsessed with this band that dresses like a psychophysical stimulation protocol youtu.be/0Ssi-9wS1so
Catching up on #Cosyne2026 talks online. The lineup of talks this year is really strong across topics! I'm having some FOMO watching these remotely
Another perspective: someone's career can be delayed or completely ended because of delays in review. Who is to blame when reviewing papers is seen as a burden?
Despite all my rage, I'm still just a rat in space
Dendritic arbors provide neuroscience with an ideal opportunity to study how individual neurons interact with their broader circuitry and are the field’s best bet to bridge cellular and systems neuroscience, writes @justinkohare.bsky.social.
#neuroskyence
www.thetransmitter.org/dendrites/de...
With this one in print, I think I finally earned that PhD... 😅
Presented for the first time at the cosyne when the world ended (March 2020). I'll bring over a summary thread from twitter when it was still twitter...
www.sciencedirect.com/science/arti...
Congrats Dan! Great thread and paper
Thrilled to finally share this work! 🧠🔊
Using a new reinforcement-free task we show mice (like humans) extract abstract structure from sound (unsupervised) & dCA1 is causally required by building factorised, orthogonal subspaces of abstract rules.
Led by Dammy Onih!
www.biorxiv.org/content/10.6...
Fully agree! Did you try codex from openAI by any chance? I have heard mixed reviews on CC, but not sure it's because they have applied it to large coding projects, which is not the case in code we use in neuro research
Our paper is out in @natneuro.nature.com!
www.nature.com/articles/s41...
We develop a geometric theory of how neural populations support generalization across many tasks.
@zuckermanbrain.bsky.social
@flatironinstitute.org
@kempnerinstitute.bsky.social
1/14
Please share: we're hiring a new tenure-track faculty member to our Department of Genetics at Albert Einstein College of Medicine.
faculty-einstein.icims.com/jobs/17847/a...
New paper out at PNAS: www.pnas.org/doi/10.1073/...
Revisiting the high-dimensional geometry of population responses in the visual cortex with @jpillowtime.bsky.social. The review took forever because a reviewer was doubtful our new estimator can infer eigenvalues beyond the rank of the data! (1/6)
Dr Kareem Carr man: i wish to publish @kareem_carr Jan 21 reviewer 2: your paper is no good man: i'll do anything to improve reviewer 2: it's simple. you must read the work of the great scientist Pagliarini man: *bursts into tears* but i am Pagliarini Andre Pagliarini @apagliar Jan 21 a first: in rejecting an article I submitted to a journal, reviewer 2 noted I failed to engage the work of one Andre Pagliarini Jan 21, 2026 • 3:47 PM UTC
I just thought everyone should see this
excerpt from PDF file showing the mouse cursor floating over "cvPCs" causing the words "cross-validated principal components" to appear
A humble proposal: all abbreviations in scientific papers should use PDF tooltips to expand the abbreviation when the mouse pointer hovers over them.
Anyone agree/disagree?
A screenshot from Rick Astley's Never Gonna Give you up music video
A screenshot from Rick Astley's Never Gonna Give you up music video
A screenshot from Rick Astley's Never Gonna Give you up music video
A photograph of the seminary gym in knives out. It has the same window.
Just watched the new Knives Out and I think it's really important you know that the scene in the Seminary's Gym is filmed in the same place Rick Astley filmed the music video for Never Gonna Give You Up.
I saw the window tracery and immediately made my friends pause the film so I could tell them.
Great read for the holidays. My own q: Is the brain area framework the phrenology 2.0?
This looks super interesting! biorxiv server is down for me, but I'm interested to know how these written in stone sequences play back during behavior/task. The first thing that comes to mind is George Dragoi's ideas of pre-play and pre-established neural grammar (in hippocampus).
it appears your manuscript "in preparation" was not published in 2025 after all, mr. bond
Winter solstice is a great 'landmark' to start the holiday break
Tray full of airplane-shaped sugar cookies shaped decorated with red sprinkles
Close-up of one airplane-shaped sugar cookie decorated with red sprinkles
Survivorship Bias Sugar Cookies for the Human Genetics Department Holiday Baking Extravaganza
🧠📢 New preprint alert
Large-scale ephys is exploding but spike sorting remains the computational bottleneck. A 2-hr, 6-probe Neuropixels 2.0 Quad Base session can take over a week to sort on a single machine. Here's a better solution. 🧵
#neuroskyence #compneurosky
I sure hope publication fees are not sponsoring this
Also, thread numbering with 0-index 🤌🏾
I find it particularly interesting that thalamocortical communication seems to happen in the residual dimensions. This matches ideas from Semedo2019 about communication subspace =\= main subspaces
The whole paper is thought provoking, and congrats to @ulisespereirao.bsky.social. I recommend people to read it entirely before claiming it against the manifold hypothesis, out of ~thousands of cells, 10 dimensions explained most of the variance
Petition to change neuroskyence feed emoji from 🧠📈 to 🧟🧠 to avoid the BTC/finance bro's posting
This 2017 preprint by @suryaganguli.bsky.social is foundational: the dimension of a neural code can't be > that of the experiment used to measure it. Yet it is not very widely known. Maybe because people don't like the message? And because it's "unpublished"? (After writing it, Gao left for SpaceX)
