Nya borföreningar öppnar för enklare läkemedelsutveckling Ett stort kliv mot enklare läkemedelsutveckling har tagits på Göteborgs universitet. I en ny studie har forskare utvecklat stabila bor-flourföreningar som gör det möjligt att öka effekten eller minska...

Ett stort kliv mot enklare läkemedelsutveckling har tagits på Göteborgs universitet. I en ny studie i @angewandtechemie.bsky.social har forskare utvecklat stabila bor-flourföreningar som gör det möjligt att öka effekten eller minska biverkningarna utan att plocka isär medicinen.
shorturl.at/90j3R

Excellent presentation!!

A quick reminder for next weeks Sahlgrenska Academy & Molecular Life Science Seminar with @olallalab.bsky.social from University of Marburg on 19th of December at 15:00.

Additionally broadcasted on zoom: gu-se.zoom.us/s/62649684120

Site Selective Boron Directed Ortho Benzylation of N-Aryl Amides: Access to Structurally Diversified Dibenzoazepines We present a highly selective protocol for the ortho benzylation of N-aryl amides. This method offers mild conditions, excellent site specificity, and scalability, enabling the synthesis of diarylmethane amides and dibenzoazepines. The protocol allows for one-pot diagonal dibenzylation of dianilides, creating valuable precursors for pharmaceutically active compounds and addressing limitations in current direct C–H activation methodologies.

🧪 Excited to share our latest research breakthrough: "Site-Selective Boron-Directed Ortho Benzylation of N-Aryl Amides: Access to Structurally Diversified Dibenzoazepines" Many thanks to the incredible team for an excellent job. It is OA so go ahead and click on the link pubs.acs.org/doi/abs/10.1...

Ortho Arylation of N‐Aryl Amides and the Construction of Diagonal Tetraarylbenzenediamines and N‐Doped Fulminenes via BBr3‐Derived Dibromoboracycles We report the discovery of a boron-driven ortho-arylation reaction of N-aryl amides and ureas. This novel method enables directed borylation of a wide range of substrates, leading to the synthesis of...

New publication🧪🧪🧪

We’re excited to share our latest work: Ortho Arylation of N-Aryl Amides and the Construction of Diagonal Tetraarylbenzenediamines and N-Doped Fulminenes via BBr₃-Derived Dibromoboracycles

chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...

#OranicChemistry #Organoboron