Second of two: I then was able to talk at UCLA, hosted by another great, Keith Vossel who has done so much in AD research. Many thanks to all to come and ask great questions!Also those who helped like Kristin Valleja and Emily Yin at UCI and Brittany at UCLA. Hope to see you again soon!

First of two: I am excited to have had the chance to share our findings about the role of the dentate gyrus and acetylcholine in Alzheimer’s disease with the outstanding neuroscientists at the University of California Irvine Center for Learning and Memory led by the superb Mike Yassa.

Testosterone and 17β-estradiol regulate hippocampal area CA3 sharp waves in male and female rats - PubMed Sharp wave-ripples (SPW-Rs) are critical to hippocampal function, and the same is true of gonadal steroids, but the interactions are unclear. We find that surgical removal of the gonads greatly reduce...

I am excited to share pubmed.ncbi.nlm.nih.gov/40632653/. It shows that hormones regulate hippocampal sharp-wave ripples (SPW-Rs). 1) Removing gonads decreases SPW-Rs. Hormone replacement led to recovery. 2) SPW-Rs show sex differences. And there is more! Huge thanks to all authors!