Excited to share our new Perspective in @natchembio.nature.com with @Yang_J_lab.

How do we move from isolated cysteine modifications to a systems-level understanding of redox signaling? We outline a unified chemical framework for decoding the cysteine redoxome.

Read here: t.co/6XY1FCdtN6

Always exciting to see physical–organic sulfur chemistry in @ChemBioChem – isolable cysteine sulfenyl iodide in a “molecular cradle” as a hyper-electrophilic sulfenic-acid sibling and Cys–Trp gateway, reshaping ideas about halogen-mediated Cys oxidation.
🔗 doi.org/10.1002/cbic...

Always great to see rigorous mechanistic work in sulfur probe chemistry from @mdpluth.bsky.social.

This study clarifies that thiophene-ester probes respond to thiols & esterases—not H₂S—helping sharpen design principles across the redox probe field.

🔗 doi.org/10.1021/acsc...

A thoughtful contribution from the Xian Lab.

Phthalimide-based sulfur transfer reagents that install trisulfides on biothiols and proteins under mild, biologically relevant conditions.

doi.org/10.1039/d5ob...