The New England Journal of Medicine Apixaban for Extended Treatment of Provoked Venous Thromboembolism A Research Summary based on Piazza G et al. | 10.1056/NEJMoa2509426 | Published on August 30, 2025 Visual representations of the patients in the trial and the treatments they were assigned. Read the full Research Summary at NEJM.org.
In patients with provoked venous thromboembolism and ongoing risk factors, extended treatment with low-dose apixaban for 12 months resulted in a lower risk of recurrent VTE than placebo, with a low risk of major bleeding. Full HI-PRO trial results and Research Summary: nej.md/4p6tIDo