Beautiful, always love seeing the sectioning through the network! Feels like a greatest hits from the lab as well!

🚨NEW EPISODE🚨

How do we map the #brain at molecular resolution?

@sventruckenbrodt.bsky.social Dr. Sven Truckenbrodt explains #connectomics, #expansion microscopy, neuronal barcoding, and why scaling brain mapping is still a major challenge.

🔗Link to the video: youtu.be/a4qpFpjnOX4

Spectacular! Love the showcase.

The E11 Bio team is headed to Society for Neuroscience #Sfn2025! Come talk circuit mapping, protein barcodes, expansion microscopy, and optical connectomics at our booth (#4015) and posters!

More info: e11.bio/sfn
Ask us about our reception!

Spectacular!

6

Incredible imaging!

Fantastic, very beautiful work! Great to see it out in the world, congrats!

A new probe for actin compatible with ExM! Great work, congrats to all.

Love the video! Very cool, congrats.

E11 seeks a research associate with experience in fluorescence microscopy and tissue sectioning for our sample processing team. Work at a Focused Research Organization with great people, solid benefits, and tons of energy to complete the first mammalian connectome.

jobs.lever.co/convergentre...

E11 Bio is launching Volara: an open-source Python library for block-wise processing of large volumetric microscopy datasets! 🧪🔬

Volara features block-wise task abstractions, making scalable image processing more accessible, robust, and repeatable.

Read more: e11.bio/blog/volara

Opinion | DOGE Needs a Different Playbook for Science We need less administrative bloat in science.

"Organizations like @hhmijanelia.bsky.social, the @arcinstitute.org, and a whole class of nonprofit start-ups called focused research organizations are instead using philanthropic dollars to build tools that could accelerate scientific progress."

www.nytimes.com/2025/03/19/o...

Can we treat brain disorders by restoring neural connections?

For centuries, neuroscientists could only guess. But connectomics—a method seeking to create a 3D model of every neural connection in the brain—is moving closer to providing answers.

E11 Bio is at the forefront...🧵

Our work in connectomics is featured in @asimovpress.bsky.social! We’re building new tools to map the brain with greater precision and scale!

🚀 We are looking for Image Data Scientists to join our mission to advance connectomics towards whole brain scale for humans and other mammals (1/3) 🚀

Beautiful work! Will definitely check it out.

‘Expansion microscopy’ turns ten: how a tissue-swelling method brought super-resolution imaging to the masses A decade in, expansion microscopy is unlocking insights across biology and medicine.

‘Expansion microscopy’ turns ten: how a tissue-swelling method brought super-resolution imaging to the masses

@nature.com
@natureportfolio.bsky.social

🧪
www.nature.com/articles/d41...

Beautiful work @jpassmore.bsky.social!

Expansion Microscopy is always amazing to me - here is a dividing U2OS cell expanded ~10X and imaged using a 25X objective! 🔬 A total protein stain using maleimide gives further context. #FluorescenceFriday

Today we are sharing the progress we have made towards dramatically reducing the cost of whole-brain connectomes! We believe this is vital for unlocking new disease treatments and human-like AI. Extremely proud of the team we have built at E11 Bio🔥!

🧪 E11 Bio is excited to share a major step towards brain mapping at 100x lower cost, making whole-brain connectomics at human & mouse scale feasible (🧠→🔬→💻). Critical for curing brain disorders, building human-like AI systems, and even simulating human brains.

Read more: e11.bio/news/roadmap

Mapping and understanding the human brain is the path to AI safety! Check out @patrickmineault.bsky.social & Amaranth Foundation's roadmap, which includes our work at @e11bio.bsky.social