It’s #NMRweekend time! 🧲⁉️
Can you identify the correct structure based on the spectrum?
Drop your answer in the comments 👇. I’ll post the full explanation in a few days. 😉
#nmr #nmrchat #chemistry #quiz
Why supplement?
Creatine Monohydrate is the gold standard. It’s scientifically proven to boost explosive power, increase lean muscle mass through cell hydration, and even support cognitive function. 🧠
• Where to find it? Naturally in red meat and fish, though your body synthesizes about 1g/day in the liver and kidneys.
• How it works: It rapidly regenerates ATP (your body’s energy currency) during high-intensity bursts of activity.
The Spectral Profile:
The sharp signals you see at 3.80 ppm and 2.91 ppm are the unique “fingerprints” of creatine’s structure.
Fast Facts:
• What is it? An organic nitrogenous acid that acts as a primary energy buffer in our cells.
Creatine: From Molecule to Muscle 🧬💪
What you’re looking at is the “molecular ID card” of one of the most researched supplements in the world, captured via NMR spectroscopy.
🧵👇
#nmr #spectroscopy #sportsupplements #creatine
RT nmr_spectroscopy / Organic Chemistry ⌬🇺🇦 @nmrspectroscopy.bsky.social Our latest NMR Challenge is out 🥳 @EnamineLtd @AnalBioanalChem LINK: https://link.springer.com/article/10.1007/s00216-025-06224-0
RT nmr_spectroscopy / Organic Chemistry ⌬🇺🇦
@nmrspectroscopy.bsky.social Our latest NMR Challenge is out 🥳 @EnamineLtd @AnalBioanalChem
LINK: link.springer.com/article/10.1...
#NMRchat 🧲
Zoom-ins help uncover the fine structure of these crowded regions — a great example of the complexity of natural mixtures captured by NMR.
The region between 3.0–5.3 ppm is packed with signals from sugars like glucose and fructose.
You can also spot additional small molecules — amino acids, other organic acids, and possibly traces of aroma compounds — especially in the aliphatic region (0.5–2.5 ppm). 👇🧵
🍋 ¹H NMR of Lemon Juice
Freshly squeezed science!
This proton NMR spectrum of lemon juice reveals a rich mixture of natural metabolites. The intense multiplets around 2.6–2.8 ppm are from citric acid, the dominant organic acid in lemon.
#NMR #nmrchat #chemistry 👇🧵
My standard speed on this QNP-equipped Bruker is 100–150 routine ¹H spectra per hour (not ideal quality, of course — Z1 + Z2). Most folks don’t believe me 🤣
UPD ✅: The correct answer is C. The methyl group appears as a doublet, indicating coupling to a CH (eliminating structure A). The aldehyde signal is also a doublet with ³J = 1.5 Hz, indicating coupling to a CH (eliminating structure B).
It’s #NMRweekend ⁉️🧲 Write your answers in the comments section 👇. Note: This is an experimental spectrum. The explanation for the challenge will be published in a few days 😉.
#nmr #nmrchat #chemistry #organicchemistry #spectroscopy #quiz #nmrchallenge #nmrquiz
Spin coupling of fluorine to 4 chemically inequivalent Hydrogens
dddd )
Fluorine in bicyclic molecules looks mind blowing 🤯.
#nmr #nmrchat #chemistry #science
Multiplet of the week 🧲 ᗑ. This particular proton has four couplings to the ¹H nuclei of two diastereotopic CH₂ groups (³J = 4.95, 5.66, 6.00, and 7.28 Hz) and a ³J coupling of 6.63 Hz to the methyl protons.
#nmr #nmrchat #spin #coupling #chemistry #organicchemistry #spectroscopy
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Just insane 🤯. MNova calculated it as “m” 🙂. But I didn’t give up and extracted all couplings separately 👌. Its CH signal at the chiral centre bonded to 2XCH₂ and CH₃ 🤌🤌🤌
#nmr #nmrchat
Damn that’s true 🤣🤣🤣
#nmrchat
nmr challenge
Analytical and Bioanalytical Chemistry, NMR Challenge, by Andrii V. Kozytskyi @nmrspectroscopy.bsky.social & Volodymyr V. Tymoschuk #Enamine Substituted piperidine challenge, submit your answer for a chance to win a Springer book up to €100 link.springer.com/article/10.1... #NMRchat #NMR 🧲
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My colleague is definitely having fun with his 3D printer) #nmr #nmrchat @brukercorporation.bsky.social
🧲🧐 @uea-nmr.bsky.social bsky.app/profile/nmr9...
