I’m happy to share our new paper (with @mbartos.bsky.social) now out in Nature Neuroscience:
"The dentate gyrus efficiently converges LEC and MEC inputs into multimodal, highly specific and reliable environmental representations"

Download it @ rdcu.be/famDE

More below 🧵

Congrats, Ole! Great news!

“I'm excited to start this fellowship at the Sainsbury Wellcome Centre, studying how the brain turns knowledge of where you are into decisions about where to go next.” – Dr Ole Christian Sylte

Congratulations to @olechsylte.bsky.social on receiving a Marie Skłodowska-Curie Actions (MSCA) Postdoctoral Fellowship! 🎉

Ole will investigate how the brain transforms spatial knowledge into goal-directed actions.

We are hiring postdocs to work on representational drift and network dynamics (ERC-funded project using calcium imaging /neuropixels). If you are interested, please get in touch!

Here is the link to the official job ad:
www.uni-saarland.de/fileadmin/up...

Rätselhaftes Gehirn: Zwei Zelltypen arbeiten zusammen gegen das Vergessen NANO vom 8. Dezember: Im Gehirn entscheiden Prinzipalzellen und hemmende Nervenzellen gemeinsam über unsere Erinnerungen. Versagt ihr Zusammenspiel, steht das ganze System auf der Kippe.

Excited to share that our IN-CODE interneuron research is featured in NANO, the science program from ZDF! Big thanks to Max Lebsanft and @mbartos.bsky.social for bringing neuroscience to a wider audience!
www.zdf.de/video/magazi...

Happy and honoured to receive an ERC Consolidator Grant for our research on representational drift!

Postdocs interested to join this journey (ideally with prior experience in in vivo ephys/imaging): please get in touch, there will be openings soon…

Fantastic symposium on circuit function last week here at CIPMM. Thanks to our guests Kristina Lippmann, Magdalene Schlesiger, Fiona Muellner and @juliaveit.bsky.social for sharing their latest on synaptic function, interneuron & pyramidal cell networks and long-range communication.

See below for the latest results from the lab! Led by @susannebabl.bsky.social with support from @dfg.de and @for5159.bsky.social

Engaging poster session at the IN-Code retreat. Thanks to our SAB members and all researchers of the CRC for their interest! All students did a great job presenting their projects. @mbartos.bsky.social @uni-freiburg.de @biologyunifreiburg.bsky.social

Conjoint generalized and trajectory-specific coding of task structure by prefrontal neurons Neurons in the medial prefrontal cortex (mPFC) show spatially modulated activities. Muysers et al. show that mPFC neurons fall into distinct functional classes that differ in terms of their spatial tu...

New paper out! We found functional neuron classes in the mPFC with different spatial tuning properties (generalised vs. trajectory-specific) and distinct contribution to the encoding of task space. Great job by the first author Hannah!
www.cell.com/cell-reports...

Representational drift in CA1? We find hidden features of stability in the internal geometry of population activity, which might help to maintain a stable downstream readout. Now preprinted thanks to a great collaboration w/ @olechsylte.bsky.social , @antjekilias.bsky.social and Marlene Bartos. 👇

Our new preprint on long-term low-frequency stimulation in MTLE is online. We show that LFS has lasting effects on seizures even during stimulation-free periods and induces ultrastructural changes at the PP synapse.

Thanks a lot!

I am honoured to join Saarland University as Professor of Physiology in February 2025. My department will focus on the network mechanisms of learning, with particular interest in synaptic function & computations of large neuronal populations. We are hiring, so feel free to get in touch!