Barkley parkrun

Let's be real: Pale Guy will stay pale.

Near zero chance of any Olympic athlete found talking to a trash can, so... 🤷🏻‍♂️

That was my initial thought too

This is just to say

I have eaten
the runners
that were in
the forest

And which
you were probably
tracking
for inspo

Forgive me
they were delicious
so sweet
And so lost

#BM100 #BM100fangirling

He's just a little guy

#bm100 @keithdunn.bsky.social

I always have this cognitive dissonance as well

A quick search suggests it's about 5°C and sunny, so beautiful weather imo. Tomorrow looks like a lot of rain though...

Go for it! I just stuck words on a pic of Laz 🤷🏻‍♂️

Photo of Lazarus Lake with text reading: Roses are red Violets are blue I want to go on a Fun Run with you

Valentine's Day?
Family Day long weekend?
Ah, you mean "the Barkley Marathons has started"!
#bm100

Photo of Paul Sheppard standing in front of a grey brick wall

Don't miss @paulsheppard.bsky.social's visually innovative poem "a n y w a y (s)" in Issue 32! Excerpting doesn't do it justice; just click through to the poem:

www.thetemzreview.com/sheppard-32....

Meme depicting Geordi La Forge from Star Trek TNG confronted with the touchscreen cognitive judgement bias images

It's tragic, but I forgot to post this Good Meme when the touchscreen cognitive judgement bias paper came out.
(paper link for context: www.nature.com/articles/s41...)

Certificate for 2nd place male 30-39 in the 56km race

Yeehaw!

Paul standing in a lake after his race showing off his medal

Paul's results. Ran the 56km in 7 hours 17 minutes, landing him in 9th overall and 2nd in his division (M30-39)

I ran my first ultra distance race today, an intense and technical 56km @limberlosttrailrun.bsky.social . It was HOT and I learned a lot of things that I'll do differently next time, but it was some great Type 2 Fun!

It was hot, humid, then rainy; it was a lot. I wanted to go farther in the 4h but it wasn't in the cards today. But what a fun concept and a fun race!

Picture of four pictures of Paul from each hour of The Farthest

Today I ran just shy of a marathon during a race called The Farthest put on by Persistence Racing. Everyone started from the same point and ran in whatever direction they wanted to get the farthest as the crow flies within 2, 4, or 8h. I did the 4h "Half-Farthest".

It must be really frustrating for those who were on search committees that had their searches cancelled to see this. It's a lot of work!

From canceled faculty hiring searches to this in <6 months... 👀

In case you were wondering (you 100% weren't): the mouse in the graphical abstract is "greyer mouse" because "grey mouse" just wasn't grey enough for certain co-authors who will go unnamed...

Purinergic receptor activation rectifies autism-associated endothelial dysfunction Early cerebrovascular alterations affect brain maturation by impacting trophic support and energy supply. Recent evidence in a 16p11.2 deletion mouse model of autism spectrum disorder (ASD) revealed b...

Happy to share the current version of our latest story, currently under peer review. Cool collab with @dablab.bsky.social @manickam-lab.bsky.social and others. We are not only understanding endothelial deficits in an #autism model, but now also capable of rescuing them! #16p11.2 #treatment #P2Y2

So check it out! And many thanks to the whole crew that worked on this! @westernubrainscan.bsky.social @timbussey.bsky.social @lisasaksida.bsky.social @maximoprado.bsky.social @touchscreencog.bsky.social @tcnlab.bsky.social

We also present some interesting data regarding a knock-in model often used as a control for this amyloidopathy model since they do not develop plaques. We found that despite this lack of plaque development, they show more profound decreases in cognitive flexibility across age compared to wildtypes.

We show herein that a mouse model of aggressive amyloidopathy can learn to discriminate visual cues, but, following learning, are deficit in reversing what they've learned (cognitive flexibility) and show perseverative responding.

Impaired Cognitive Flexibility With Preserved Learning in an Amyloid Precursor Protein Knock‐In Mouse Model of Amyloidopathy The amyloid precursor protein knock-in mouse model of amyloidopathy (AppNL-G-F/NL-G-F) was assessed on touchscreen-based learning and cognitive flexibility tasks in comparison with both AppNL/NL and ....

🚨 NEW PAPER ALERT 🚨
🚨 KLAXON KLAXON 🚨

Impaired Cognitive Flexibility With Preserved Learning in an Amyloid Precursor Protein Knock-In Mouse Model of Amyloidopathy

onlinelibrary.wiley.com/doi/10.1111/...

Well done to all of our affiliated presenters at this year's @canacn.bsky.social Meeting! Great work!

Integrating optical neuroscience tools into touchscreen operant systems - Nature Protocols This protocol extension enables researchers to integrate optically based manipulation and measurement techniques into their touchscreen experimental systems, focusing on optogenetic manipulation, fibe...

This is finally out! Great collaboration with Andy Holmes @timbussey.bsky.social @lisasaksida.bsky.social and @touchscreencog.bsky.social @westernubrainscan.bsky.social trainees www.nature.com/articles/s41...