Reverse molecular pharmacology identifies the non-canonical axis of IRAK as a chemoresistance factor in neuroblastoma www.biorxiv.org/content/10.64898/2026.01...

Reverse molecular pharmacology identifies the non-canonical axis of IRAK as a chemoresistance factor in neuroblastoma www.biorxiv.org/content/10.64898/2026.01...

Depuis plusieurs années, le mois de septembre est dédié à la lutte contre les cancers de l’enfant, de l'adolescent et du jeune adulte (AJA). Pour parvenir à guérir plus et mieux, parlez en autour de vous et faites entendre la voix des enfants malades.

He is doing pretty good 😜.

Structured Exercise after Adjuvant Chemotherapy for Colon Cancer | NEJM Preclinical and observational studies suggest that exercise may improve cancer outcomes. However, definitive level 1 evidence is lacking. In this phase 3, randomized trial conducted at 55 centers, ...

This study is another POC for the interest of our program realized through @southrock.bsky.social evaluating the physical activities in children diagnosed with cancer.

Structured Exercise after Adjuvant Chemotherapy for Colon Cancer | New England Journal of Medicine www.nejm.org/doi/full/10....

One picture is worth a thousand words

📣 Youth4Kids 2025 🎗️ @r4knetwork.bsky.social

This morning, we had the pleasure to welcome Dr Clara Savary from @hmriaustralia.bsky.social.

She is currently working on deciphering the resistance mechanisms of ONC201 in DIPG.

Well done Clara and the whole team led by Dr Matt Dun. 👏

📣 Youth4Kids 2025 🎗️Best young researcher talk 🤩

Second part of the contest. Five new candidates will be presenting their work.

@r4knetwork.bsky.social

📣 Youth4Kids 2025 🎗️Best young researcher talk 🤩

This year, 10 candidates will be presenting their work. They will be judged by young postdocs from the @r4knetwork.bsky.social.

We are starting this morning with 4 PhD candidates.

Good luck to all candidates.

📣 Youth4Kids 2025 🎗️

Let's start with @guixe-m.bsky.social from @irbbarcelona.org. Her work focuses on the origin of second malignancies in children or the factors underlying the response to immunotherapies.

Looking forward to listening to her talk!

@r4knetwork.bsky.social

Here we go again!! 🤩

Today is the first day of Youth4Kids 2025!!! An online congress organized by the young researchers of @r4knetwork.bsky.social. Great keynote speakers, selected talks from young researchers and the highlight of the event, the Youth4Kids Doctoral Grant Competition!!!

Prospective, multicenter validation of a platform for rapid molecular profiling of central nervous system tumors - Nature Medicine Application of a nanopore sequencing workflow for real-time analysis of brain tumors results in molecular classification within a 30-minute intraoperative window, followed by comprehensive profiling w...

In this week’s publication highlights, we picked this study just out @naturemedicine.bsky.social describing an innovative method for the rapid classification of brain tumors based on molecular profiling.

Congrats to all involved @dkfz.bsky.social and beyond 👏🏻

www.nature.com/articles/s41...

Looking for heart shapes in the lab and in life in general.

Life is full of beauty. Notice it.

🥰🥰

For the first time of the year, the whole team got together for the #REMAP4Kids Mini-Symposium.

Full afternoon of short presentations to highlight the different projects ongoing in the team. Very exciting to see how our team is progressing over the years, thanks to our collaborations & funders.

Today, members of @r4knetwork.bsky.social gave presentations to school pupils all across the country.

We’re teaching young kids about medical research & what it means to be a scientist.

Always a great pleasure and even more so with our brand new lab member @mathilde-krh.bsky.social 🤩.

Des moments toujours riches et passionnants. Vivement l’an prochain 😊.
@eddpasquier.bsky.social
@mathilde-krh.bsky.social
@crcm.bsky.social
@inserm.fr
@univ-amu.fr

Une semaine dans toute la France pour sensibiliser 2500 enfants, en hommage aux 2500 enfants et adolescents diagnostiqués chaque année en France avec un cancer.

Un petit galet peint est symboliquement remis à chaque enfant avec l’idée que contre le cancer, chacun peut amener sa pierre.

Chaque année au mois de Mars, sous l’impulsion 2500 Voix les chercheurs du réseau React4Kids se mobilisent pour sensibiliser les enfants des classes primaires et collèges sur la recherche, le cancer et leur donner envie de s’engager dans des métiers au service des autres.

Our collabs are the best!

Headed by Laura Broutier from CRCL & funded by INCa, this collaborative project uses patient-derived tumoroids, drug screening and mathematical modeling to develop more effective treatments for #Rhabdomyosarcoma.

This is so @southrock.bsky.social 🤩

Every single one of these meetings is an absolute pleasure.

I feel privileged to coordinate this Center of Excellence with @marie-castets.bsky.social and to get to build collaborative projects with the likes of @cedricmaurange.bsky.social @delloye-bourgeois.bsky.social & many more not on BlueSky.

Selfie of 3 persons at a « Stand up for Science » March in the middle of a crowd of pacific demonstrator. One of the 3 persons is holding a sign that says « more labcoats and less white robes » written in French and showing an actual labcoat next to KKK white robes.

It’s the start of a new week.

But we still want more labcoats and less white robes.

We need to keep standing up for science!

@standupforscience.bsky.social
@marionlegrand.bsky.social
@rafajarguello.bsky.social
@cnrs.fr @inserm.fr @univ-amu.fr
@crcm.bsky.social @ciml.bsky.social
#Medsky

A world free of discrimination, where diversity would be a strength and not weakness. A world where all children, all women, all human beings would be free from violence, exploitation, abuse and neglect. A world where kindness, tolerance and empathy would be great values, the most important ones.

Today is the International Women's Day 2025.

The world we are currently living in scared me a little more every day, but collectively, I still do think that we can make a difference.

I wish we could live in a gender equal world.

#IWD2025

Today, I protested against Trump administration’s science policies.
Science, all types of science, shapes our world, our futur world. We need to protect it. Science always matters.

@standupforscifr.bsky.social
@crcm.bsky.social
@cnrs.fr @inserm.fr

More white coats, less white robes! @eddpasquier.bsky.social #standupforscience #standupforscience2025

Je serai présente au rassemblement marseillais du mouvement #StandUpForScienceFrance ce vendredi.
 
Mobilisons nous pour défendre les sciences et les humanités, la liberté académique, la recherche et l’enseignement.

Inhibition of the STAT3/Fanconi anemia axis is synthetic lethal with PARP inhibition in breast cancer - Nature Communications Targeting cancer stem cells (CSCs) has great potential in anti-cancer treatment. Here this group reports the role of antibiotic Nifuroxazide as a potent anti-CSC compound and fabricates it into an ant...

Glad to have contributed to this beautiful work led by @celiarouault.bsky.social & colleagues at @crcm.bsky.social just out in @naturecomms.bsky.social. Using drug repurposing, they unveiled the STAT3/FanA axis as a targetable vulnerability in breast cancer stem cells

www.nature.com/articles/s41...

Today, all 3 centers of excellence in pediatric oncology research were invited by INCa to present what they have been up to during their first year of existence.

We were delighted to showcase everything we have put in place, including our beloved #RockBands, ongoing and upcoming projects.