Psychedelics Don’t “Shut Down” the Brain—They Connect It Researchers combined hundreds of brain scans from five psychedelics to identify a single neural signature. Rather than silencing activity, these drugs consistently increased communication between high...

McGill University study used computational analysis of human brain scans and not flawed animal studies to show psychedelics boost brain connectivity rather than suppress it.
www.technologynetworks.com/drug-discove...

Fat Promotes Aggressive Breast Cancer Growth High-fat conditions caused tumors to develop invasive, tendril-like structures in 3D models. While growth rates remained similar, gene activity linked to tissue breakdown increased, indicating how die...

Princeton University finds high-fat conditions make breast cancer more aggressive using human-based tumor models.
www.technologynetworks.com/cancer-resea...

Deep Learning Model Predicts How Individual Cells Influence Disease Outcomes A computational method called scSurv links individual cells to patient outcomes using widely available bulk RNA sequencing data.

Institute of Science Tokyo’s AI model uses human cell data to predict disease outcomes, helping identify harmful cells and guide targeted therapies. www.technologynetworks.com/informatics/...

Stroke triggers a hidden brain change that looks like rejuvenation After a stroke, the brain may do something surprisingly hopeful—it can “refresh” parts of itself. Researchers analyzing brain scans from over 500 stroke survivors found that while the damaged side of ...

Human research from the Keck School of Medicine of USC used AI + MRI data from 500+ patients to reveal how the brain reorganizes after stroke to compensate for injury. www.sciencedaily.com/releases/202...

Stroke triggers a hidden brain change that looks like rejuvenation After a stroke, the brain may do something surprisingly hopeful—it can “refresh” parts of itself. Researchers analyzing brain scans from over 500 stroke survivors found that while the damaged side of ...

Human research from the Keck School of Medicine of USC used AI + MRI data from 500+ patients to reveal how the brain reorganizes after stroke to compensate for injury. www.sciencedaily.com/releases/202...

The Moon Astronauts Brought Along USB Stick-Sized Living Samples of Their Own Tissue The crew of NASA's Artemis II mission are carrying live organ chips made of their own bone marrow out to deep space.

NASA’s Artemis II used human bone marrow cell-based organ chips to study space radiation, delivering more accurate and human-relevant insights than outdated experiments sending animals into space.
futurism.com/space/nasa-a...

'Cervix-on-a-Chip' Brings STI Research Closer to Real Human Biology Researchers develop the first immune-capable cervix-on-a-chip, enabling realistic study of sexually transmitted infections.

University of Maryland School of Medicine developed a cervix-on-a-chip using human cells to study sexually transmitted infections without cruel and inadequate animal tests.
www.insideprecisionmedicine.com/topics/preci...

Organ-on-a-chip technology replicates decades of human aging in just four days Over one billion people worldwide are over 60, and the population is projected to more than double by 2050. But as more people live into their 60s, 70s, and 80s, health care systems across the globe m...

UC Berkeley created an organ-on-a-chip using human cells to replicate decades of aging in days, delivering more humane and scientifically accurate insights than animal testing. medicalxpress.com/news/2026-03...

University of Colorado Boulder studied the effect of the sugar substitute erythritol on human brain cells and not outdated animal models to show that erythritol increases risk of stroke by disrupting brain vessel cells and clot breakdown.
www.sciencedaily.com/releases/202...

Tell NYU that cruel and deadly experiments on pregnant mice must end! www.caareusa.org/nyu_stands_b...

Genetic "Scars" in Cancer DNA Mapped Scientists have, for the first time, decoded the full range of mutations that drive tumor growth, paving the way for a new era in precision medicine.

Studying human tumors and not imprecise animal models, scientists at the University of Manchester have for the first time decoded all mutations behind tumor growth, potentially launching a new era of precision medicine.
www.technologynetworks.com/cancer-resea...

New Biomarker in Cerebrospinal Fluid Improves Diagnosis of Dementia With Lewy Bodies Scientists have discovered a new quantitative biomarker in lumbar fluid that is helping doctors to diagnose Parkinson's disease and Lewy body dementia more accurately.

Using human samples and not outdated animal tests, Amsterdam UMC identified a CSF biomarker that improves Parkinson’s and Lewy body dementia diagnosis.
www.technologynetworks.com/diagnostics/...

Sugary Drink Intake Linked to Anxiety in Young People Learn how regularly drinking sugary drinks has been linked to a 34% higher risk of anxiety symptoms in teens.

Lebanese American University links sugary drinks to higher anxiety risk in youth, using human-based data offering more reliable and ethical insight than animal testing www.technologynetworks.com/applied-scie...

Diagnostic Markers for Multiple Sclerosis Discovered Researchers have identified a set of 22 proteins that distinguish multiple sclerosis from other inflammatory diseases.

In animal free research, Technical University of Munich used proteomics to analyze CSF from 5,000 patients, identifying new MS biomarkers, enabling earlier, more accurate MS diagnosis and timely treatment.
www.technologynetworks.com/diagnostics/...

Exercise Changes Memory-Related Brain Activity in Minutes Researchers recorded brain activity directly in epilepsy patients and found that a short cycling session increased hippocampal sharp-wave ripples—neural rhythms linked to memory.

University of Iowa shows exercise boosts memory brain activity within minutes using human brain recordings—more reliable and ethical than animal testing
www.technologynetworks.com/neuroscience...

Daily Multivitamins May Slightly Slow Biological Aging A randomized clinical trial found that daily multivitamin use modestly slowed biological aging in older adults based on two DNA methylation clocks. Participants taking multivitamins showed a reduced p...

Brigham and Women’s Hospital finds multivitamins modestly slow biological aging in a human trial, advancing more relevant and ethical research than animal testing
www.technologynetworks.com/proteomics/n...

Studying human immune cells and not flawed animals, Linköping University finds a lupus drug can restore HIV-impaired immune cells.
www.technologynetworks.com/drug-discove...

AI Predicts Risk of Colorectal Cancer in Ulcerative Colitis Patients A large-scale study shows that combining AI with statistical modeling can predict which ulcerative colitis patients with precancerous lesions will develop colorectal cancer, improving surveillance pla...

UC San Diego uses AI and human patient data to predict colorectal cancer risk. Human-based methods are more ethical and more predictive than animal testing. www.technologynetworks.com/informatics/...

ADHD Isn’t One Condition—Brain Scans Suggest Three Types A large MRI study of over 3,500 children identified three biologically distinct ADHD biotypes using brain network modeling and AI clustering. Each subtype showed unique brain patterns, genetic risks, ...

West China Hospital, Sichuan University used AI and brain scans from 1,150 children to identify 3 ADHD subtypes, information unobtainable from flawed animal experiments.
www.technologynetworks.com/proteomics/n...

Depression may start with an energy problem in brain cells Researchers have discovered a surprising change in how cells produce energy in people with depression. Brain and blood cells in young adults with major depressive disorder produced more energy molecul...

Studying humans and not outdated animals, researchers at the University of Queensland found that reduced ATP levels in patients with depression may disrupt brain function and contribute to symptoms, suggesting new avenues for treatment.
www.sciencedaily.com/releases/202...

Insomnia and sleep apnea together dramatically raise heart disease risk Struggling to fall asleep and stopping breathing at night may be a far riskier combo than previously thought. In a study of nearly a million veterans, researchers found that having both insomnia and s...

Yale School of Medicine studied human clinical data and not flawed animal tests to show that insomnia and sleep apnea combined can raise heart disease risk. www.sciencedaily.com/releases/202...

FDA, NIH pledge more flexibility and $150M investment for animal testing alternatives Health authorities in the U.S. | Health authorities in the U.S. are continuing their move away from animal testing in drug development, with the FDA signaling an openness to new approaches that haven’...

The FDA and NIH are advancing non-animal testing with new guidance, $150M funding, and increased flexibility, marking a shift toward humane science in research and drug development.
www.fiercebiotech.com/biotech/fda-...

Mayo Clinic discovers rare gene mutation that causes fatty liver disease Mayo Clinic researchers have identified a rare mutation in the MET gene that can directly cause metabolic dysfunction-associated steatotic liver disease. The mutation disrupts the liver’s ability to p...

Mayo Clinic researchers conducted human genomic research to identify a rare gene mutation driving fatty liver disease, vital information difficult or impossible to obtain from animal tests.
www.sciencedaily.com/releases/202...

Social Deprivation Linked to Gut Microbiome Changes People in more deprived areas had less diverse gut bacteria and fewer butyrate-producing microbes, linked to anxiety, diabetes, inflammation, and metabolic health, suggesting social conditions may sha...

King’s College London studied human data, and not cruel animal tests, to show that social deprivation is linked to less diverse gut microbiomes and higher anxiety risk.
www.technologynetworks.com/immunology/n...

AI-Boosted Electronic Nose Detects Ovarian Cancer Researchers have developed an electronic nose that can “smell” early signs of ovarian cancer in the blood. The method is precise and could eventually be used to find many different cancers.

Linköping University developed an AI electronic nose that detects ovarian cancer from human blood samples, showing how human-based research can deliver advances in patient treatment.
www.technologynetworks.com/diagnostics/...

Blood Lactate Levels Can Predict Physical Outcomes for ALS Patients Researchers have revealed that blood lactate is a key biomarker that can predict physical outcomes and prognosis in patients with ALS.

In animal-free research University of Queensland linked patient blood lactate levels to ALS progression, providing human-relevant insight that may inform treatment.
www.technologynetworks.com/diagnostics/...

Cheek Swabs Offer a Non-Invasive Path to Schizophrenia Diagnosis Researchers identified elevated Sp4 mRNA and HSP60 protein levels in cheek cells from people with schizophrenia. These biomarkers correlated with symptom severity and memory deficits, suggesting a pot...

Rutgers University identified schizophrenia biomarkers from human cheek cells, highlighting important advances obtained without outdated animal testing.
www.technologynetworks.com/proteomics/n...

COVID Vaccination During Pregnancy May Protect Against Preeclampsia A global study found COVID-19 booster vaccination during pregnancy was associated with lower odds of preeclampsia, even among women who did not develop infection. Vaccination was also linked to fewer ...

Oxford researchers used global human pregnancy data to show COVID vaccination reduces preeclampsia risk, highlighting the value of human-relevant research over animal testing.
www.technologynetworks.com/biopharma/ne...

UB Launches VISI-ON-BRAIN: Cutting-Edge Neuro Network The University of Barcelona is consolidating its position at the forefront of European research thanks to the strategic project "VISI-ON-BRAIN

The University of Barcelona launched VISI-ON-BRAIN to study brain disorders using human-relevant tools – for more ethical and predictive science than animal testing.
www.miragenews.com/ub-launches-...

Genetic Study Separates Schizophrenia and Bipolar Disorder Pathways Researchers used genomic structural equation modeling to separate schizophrenia-specific and shared bipolar genetic risks. Schizophrenia-unique variants were linked to lower IQ, while shared variants ...

King’s College London used large-scale human genomic data to distinguish schizophrenia and bipolar disorder pathways, which could lead to more targeted therapies.
www.technologynetworks.com/genomics/new...