Great culture can save lives. Literally.

Amazing letter in today’s @thetimes.com about Tom Stoppard

James Watson, dead at 97, was a scientific legend and a pariah among his peers James Watson, the co-discoverer of the structure of DNA who died Thursday at 97, was a scientific legend and a pariah among his peers.

If you read only one obit of James Watson, read this one

www.statnews.com/2025/11/07/j...

(From the late Sharon Begley, for @statnews.com )

Shocking first high impact trial of the day. Fish oil reduces CV events in dialysis patients! #Pisces #kidneywk

Simultaneous pub in NEJM

www.nejm.org/doi/full/10....

HIT 1

Today’s trials at #KidneyWk

In the morning a LBCT session at 10:30

featuring
PISCES (fish oil in dialysis!)
LIBERATE in AKI
Another AKI alerts from @fperrywilson.bsky.social
A Transplant trial
GLP1 and a Flozin analyses

And

New to the #KidneyWk Opening Plenary: two High-Impact Clinical Trials debut this morning, presenting pivotal data in CKD and IgAN. These groundbreaking studies take the main stage at Kidney Week for the first time—you don’t want to miss this.

Don’t forget to support #FOAMed and #NephJC with our annual fundraiser. Every donation helps keep us going (even as unpaid volunteers). 🫶🫶🫶
www.nephjc.com

a pink box of soft tissues with flowers on it ALT: a pink box of soft tissues with flowers on it

Tissue is the issue #nephjc

2 years? I think we need a plan for a 2 week update!

Should we have continuously updated recs based on when new evidence comes out? I think NCCN cancer guidelines are like this

#nephjc

a little girl is asking why not both while standing in a kitchen . ALT: a little girl is asking why not both while standing in a kitchen .

#nephjc

I have a hard time seeing how we progress from a smorgasbord of individually good therapies to a systematic approach as to which one(s) is (are) best for an individual patient

It’s a good problem but a problem nonetheless

#nephjc

I think it we need trials with bi-pronged approaches; it’s tough when no one company (until maybe recently) has therapies in both the immune-modulatory and general nephron preserving camps.

#nephjc

a man is saying `` i would like that very much '' while wearing a black hoodie . ALT: a man is saying `` i would like that very much '' while wearing a black hoodie .

#nephjc

Seems like presence/absence of diabetes belongs somewhere in this algorithm?

#nephjc

Complement inhibitor had been published on a year before the guidelines were released!

And who knows what’s going to happen at #kidneywk?

Is there a plan for a v2025.2?

#nephjc

Really important point here; what is the south Asian representation in trials v real world in IgA? #nephjc

an older man with a beard is clapping his hands in front of a lamp ALT: an older man with a beard is clapping his hands in front of a lamp

#nephjc

Povetacicept! I’m excited to see some new IgA data from everyone at #kidneywk but ApoL1 is still my one true love

#nephjc

Josh Waitzman—I work full-time for Vertex and part-time at BIDMC.

COI: Vertex has an ongoing trial of a BAFF/APRIL inhibitor.

Opinions are my own and I only know what’s public.

#nephjc

If treatments are available that can help at early stages of most causes of CKD (RAASi, SGLT2i, etc), why WOULDN’T we screen? Economics? How much does saving 20 years of dialysis get you? What about human costs?
www.kireports.org/article/S246...

In case folks missed this, ACGME Transplant Nephrology accreditation is now a thing!

If folks are Program Directors, they may need to start the process of accreditation soon.

Requirements here:

www.acgme.org/globalassets...

Stoners against kidney stones?

In this house we drink liquids and support #nephjc

(Maybe I should get a backpack next time)

Donate at: www.nephjc.com/news/2025/9/...

NIH Student Grant Cancellation Will Weaken Scientific Innovation The termination of federal F31 diversity fellowships puts many graduate students in a bind — and U.S. science at risk.

This is a powerful account from a PhD student whose fellowship was terminated by NIH because it was part of a "diversity" program without any other considerations or understanding of what the program or the students were actually doing.

undark.org/2025/10/09/o...

1/2

Pre #nephjc bias: Team pro protein

All these studies are deeply confounded and based in the pre-kidney-preserving therapy era.

Let them eat steak!

(Actually, let them eat vegetable sources of protein, but beans, lentils, and soy don’t rhyme with cake)

Loved watching @kidneyrebel.bsky.social grand rounds at @nu-nephrology.bsky.social!!

Thank you for the PKD mega blocks shout out #nephjc (1), happy to be at the right overlap in my Venn diagram (2), and trying to build toward a medical specialty in a hill (3)

www.youtube.com/watch?v=RlTC...

New episode of Channel Your Enthusiasm, part 2 of 3 on metabolic acidosis. Episode with chapter art, chapters, and fully referenced

www.rosebook.club/episodes/202...

NIH Leadership Is Failing Early Career Researchers Halted training programs, funding chaos, and hiring freezes jeopardize advancement options for early career researchers.

My op-ed just came out discussing how NIH leadership is failing early career researchers and, importantly, how we can push back and take our future into our own hands.

In Paul Farmer’s Beautiful Garden of Global Health Equity: Reflections on the Third Remembrance of His Passing | NEJM On the third anniversary of Paul Farmer’s death, Didi Bertrand Farmer reflects on his “beautiful garden” — a vision of social justice in health care, with deep roots in the fertile soil of equity.

Thought-provoking, well-written @nejm.org blog article by Dr. Paul Farmer's wife on the (third) anniversary of his passing: www.nejm.org/doi/10.1056/...

cc: @jwaitz.bsky.social
#nephjc summer book club chat