It is with infinite sadness that we learned of the passing of Clarisse Orniacki.

She joined @vdoye.bsky.social lab and defended her thesis in December 2022 and pursued her career with a postdoc in‬ @tedfon.bsky.social at McGill University in Montreal .

Tribute 🔗 www.ijm.fr/tribute-to-c...

Bonsai: Tree representations for distortion-free visualization and exploratory analysis of single-cell omics data Single-cell omics methods promise to revolutionize our understanding of gene regulatory processes during cell differentiation, but analysis of such data continues to pose a major challenge. Apart from...

Bonsai: Tree representations for distortion-free visualization and exploratory analysis of single-cell omics data

by @erikvannimwegen.bsky.social and colleagues:

www.biorxiv.org/content/10.1...

If you mutate 25 genes, you can make a Squire Wolf

What's happening in the USA 🇺🇸 is terrifying and for European 🇪🇺 scientists this should be a wake up call. Here are my emotional rollercoaster🎢 and my 2 cents 💶. #standupforscience

Hello, Bluesky! ☀️

We fund frontier research in Europe—bold ideas, unexpected discoveries and science that shapes the future. So it’s only fitting we’ve landed here. Sorry for being late.

Follow us for updates on ERC funding, research policy, and our grantees' discoveries.

It’s so exciting to see more and more scientific agencies and institutions joining 🦋

I feel like this is exactly what was missing on other platforms. In my opinion, it will definitely help strengthen the scientific community here! 💪🧬

Sperm epigenome in the transmission of disease from fathers to children (January 17, 2025) YouTube video by CEEHRC VideoCast

If you missed our most recent seminar with Drs. Sarah Kimmins and Mathieu Schulz, you can now find it online!

youtu.be/-CJNhM-1JhA

All of our other seminars can be found at thisisepigenetics.ca/events/semin...

What an achievment Juliane !!! 👏 Congratulations !! 🎊

Welcome! You are invited to join a webinar: CEEHRC January 17th 2025 - Kimmins. After registering, you will receive a confirmation email about joining the webinar. The Canadian Epigenetics, Environment and Health Research Consortium (CEEHRC) Network is a network run by epigenetic researchers from across Canada, funded by the Canadian Institutes of Health Researc...

We kick off 2025 with our seminar series on Friday, January 17 at 12pm ET!

We have the pleasure of hosting Drs. Sarah Kimmins and Mathieu Schulz @msclz.bsky.social where they will discuss the role of the sperm epigenome in development.

Register at:
us06web.zoom.us/webinar/regi...

www.biorxiv.org/content/10.1...
Our study published today on #bioRxiv describe the identification of a deaminase that converts 5mC to T, enabling direct sequencing of the human methylome and genome. This achievement was made possible through a collaborative effort across all departments at #NEB.

Happy to share our preprint👇
Congrats and thanks to all the co-authors 🙏

(1st post @BlueSky) Preprint alert🚨a long thread. Cautions in the use of @nanopore sequencing to map DNA modifications: officially reported “accuracy” ≠ reliable mapping in real applications. We performed a critical assessment of nanopore sequencing (across different versions of models) for the 1/n

This looks like an amazing paper ! Going right on top of my reading list ! Congrats to everyone involved ! 👏

The emergence of Sox and POU transcription factors predates the origins of animal stem cells Nature Communications - The pluripotency program is maintained by transcription factors from the Sox and POU families. Here they identify SOX and POU factors from unicellular relatives of animals...

SOX and POU are crucial Transcription Factors in animal development, believed to be innovations of this group. Here we find them in unicellular relatives of animals. And hold tight, you can use a choanoflagellate 🦠 SOX gene to make a full chimeric 🐁 ! Read more here 🧵: rdcu.be/d0dPN 1/6

I've been meaning to write a lengthy thread about our experiences with DNA methylation editing in mouse ESCs if that would be useful (or interesting?) for a niche audience here. tl;dr: it was frustrating but we learned a lot, and it ended with our shiny new pub (1/17) www.nature.com/articles/s41...