For those using dopamine sensors (in particular dLight1.3b) in vivo and want to boost signal sensitivity to capture tonic dopamine levels (See www.nature.com/articles/s41...), DETQ is now available for purchase here @hellobio.bsky.social
It was very nice to chat with you Hello Bio team ! And great news that scientists now have facilitated access to DETQ vials for experiments involving dopamine sensors (in particular dLight1.3b which is the one we validated in vivo in the lab)
Congrats Lisa !! 🎉🎉👏🏽
Preprint from (former) lab 🥳 Congrats Alina 🎉 and all co-authors!
The neurobiology of overeating and food addiction
Figure 4 shows dopamine transients when food is smelled, tasted and passed to the gut. Unlike taste-related transients, gut-related transients would remain unchanged with repeated experience. Why? We don’t really know.
www.cell.com/neuron/fullt...
old twitter posts are below 👇. dates don't match as these are tweets from long time ago, which were transferred over
🧵Excited to share our work @NatureComms @tpatriarchi
on dopamine (DA) imaging #dLight🧠 A chemogenetic approach that allows to tune the sensitivity of DA sensors on-demand to record the highs and lows of DA release in the same animal (1/n) t.co/vGVSEI8duM original twitter post x.com/LabouesseMar...
Excited to share our work at Nature Comms done in
@Kellendonk lab @Columbia on how the basal ganglia is organized. We show that D1 bridging collaterals to the GPe define a new ‘Go’ pathway that promotes motor action (1/n) t.co/mVaGuzHWbv Original twitter post: x.com/LabouesseMar...
Bold move! in the right direction
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and also huge thanks to @PeppeGanga for co-organizing
Four excellent talks at the #ECNP2022 Symposium on brain circuits for eating and metabolic disorders. A lot of fun putting this session together and co-chairing w/ Roger Adan. Thank you to ECNP for selecting us and the numerous attendees and great questions 👏
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important work on the meaning of fiber photometry signals in the striatum 👇
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Really grateful for the funding from the @BBRFoundation #NARSAD YI Grant to support our junior group studying postnatal development of feeding & reward circuits 🧠🎉Big thanks to my past/currents mentors & group members and to @ETH_en @WolfrumLab for hosting us!
interesting new work on striatal D1/D2 dichotomy in behavior, in the context of choice rejection / choice exploration 👇
t.co/PT8LS8GClN
Very interesting findings!
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Congrats Kelly @kelly_martyniuk!! &coauthors @CKellendonk @ATorresHerraez @DanLowes4 &Marcelo Rubinstein on a beautiful paper dissecting the role of dopamine in regulating striatal acetylcholine levels via D2Rs during reward behaviors! 🎉🧠👏 happy to have contributed a small bit
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inspiring thread ! on running a lab
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Fascinating work: "Dopamine subsystems that track internal states
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Thank you to the many people who stopped by our poster today #FENS2022 and gave amazing feedback! Great to finally get a chance to present this work IRL (virtual posters are just not the same)
Basal ganglia poster #FENS2022 @FENSorg - Tomorrow morning Wed 13/07, Poster 309👇👇👇🧠
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At #FENS2022 @FENSorg and interested in basal ganglia organization 🧠? Come check out our poster from @CKellendonk lab on dorsal striatum dSPN (D1-MSN) projections to the GPe (the infamous "bridging collaterals") and their roles in motor control. Poster S07-309, Wed 13/07 AM
Highly recommend anyone and everyone to watch this awesome documentary on gender bias. Even if you think you already know what's up, you can still learn something new. on netflix !
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Cool paper looking at the impact of adolescent thalamic activity on adult PFC function. Congrats to all involved!
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Very interesting work !
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Looking forward to co-chairing this symposium on Feeding circuits @ECNPtweets 2022 in Vienna !
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New fluorescent sensors for multiple neuropeptides, coming from Yulong Li lab
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Cool paper by @CarolEMorelS1 on dopamine projections to the amygdala in encoding and driving stress-induced anxiety 👇
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"An action potential initiation mechanism in distal axons for the control of dopamine release" cool paper, wow!
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This looks like good news for Gender Equality in academia in Switzerland. I look forward to seeing the numbers of women professors increasing in the next few years!
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Quick survey to take if you use or plan to use inhibitory optogenetic tools to inhibit axons or terminals 👇
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