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Posts by Mac Shine

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What a bird’s-eye view of half a million papers reveals about neuroscience New research uses artificial-intellligence-driven bibliometrics to map the structural organization of neuroscience across 25 years. The field it reveals is at once thriving and theoretically adrift.

@macshine.bsky.social talks with Mario Senden about his new project using AI-driven bibliometrics to map the structural organization of neuroscience across 25 years. The field it reveals is at once thriving and theoretically adrift. #neuroskyence

www.thetransmitter.org/methods/what...

2 weeks ago 26 6 0 1
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fMRI connectivity is dominated by recurring high-amplitude BOLD events (CAPs, QPPs)
But what originates these events? Many think neuromodulation is the culprit. Our new work offers a simpler take: cortico-cortical dynamics alone can generate CAP-like events! doi.org/10.1371/journal.pcbi.1013995
🧡1/n

1 month ago 39 17 1 0

I recently had the pleasure of chatting with @macshine.bsky.social as part of the OHBM Award Winner interview series; thanks for a great conversation! πŸ™

Catch the interview here πŸ‘‡

4 months ago 13 1 1 0

Doesn't even need an ensuite...

4 months ago 2 1 0 0
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𝗔 π—‘π—˜π—¨π—₯π—’π—˜π—–π—’π—Ÿπ—’π—šπ—œπ—–π—”π—Ÿ π—£π—˜π—₯π—¦π—£π—˜π—–π—§π—œπ—©π—˜ 𝗒𝗑 π—§π—›π—˜ 𝗣π—₯π—˜π—™π—₯π—’π—‘π—§π—”π—Ÿ 𝗖𝗒π—₯π—§π—˜π—«
By Mars and Passingham
"Understanding anthropoid foraging challenges may thus contribute to our understanding of human cognition"
Going to the top of the reading list!
doi.org/10.1016/j.ne...
#neuroskyence

6 months ago 62 16 4 2

Would love to revisit this idea if ppl are still keen. Was a fun project to work on.

6 months ago 7 0 1 0

Thanks Deb!

6 months ago 1 0 0 0

update - i found a copy. thanks all for boosting!

6 months ago 6 0 0 0

random neuroimaging question: does anyone in bluesky-land have access to the loadings for neurosynth topics in schaefer 400 (yeo7) space? #neuroskyence @misicbata.bsky.social @richardfbetzel.bsky.social @borismontreal.bsky.social @sofievalk.bsky.social

6 months ago 10 5 1 0
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Granularity of thalamic head direction cells Head direction signaling is fundamental for spatial orientation and navigation. The anterodorsal nucleus of the thalamus (ADn) contains a high density of head direction (HD) cells that process sensori...

*New preprint from the lab* – β€œGranularity of thalamic head direction cells”
doi.org/10.1101/2025...
πŸ§ πŸ“ˆ πŸ§ͺ
1/11

7 months ago 26 10 2 2
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There's lots of opportunities in the brain for closures of these kinds, though I fear that this ultimately raises another set of even-more challenging questions: namely, how do our brains decipher between different circuit closures if they differ in their constraints? Fun to think about...

7 months ago 1 0 0 0

The short answer is yes, but we were quite limited in writing that paper to keep the text short and the references mostly to the last few years. I'm certainly not an expert on circular causality/constraint closure, but I do very much like the implications of the ideas

7 months ago 0 0 1 0
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What changes and what stays the same as you scale from single neurons up to local populations of neurons up to whole brains?

Michael and Mac @macshine.bsky.social on the systems approach to study brains across scales.

braininspired.co/podcast/220/

7 months ago 23 8 0 0
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Compositional neural dynamics during reaching The complex mechanics of the arm make the neural control of reaching inherently posture dependent. Because previous reaching studies confound reach direction with final posture, it remains unknown how...

Excited to share my latest work with @jonathanamichaels.bsky.social @diedrichsenjorn.bsky.social & @andpru.bsky.social!
We asked: How does the motor cortex account for arm posture when generating movement?
Paper πŸ‘‰ www.biorxiv.org/content/10.1...
1/10

7 months ago 89 24 3 5
Video

Adaptive learning is coordinated across behaviour, time and neurobiology (from synapses and dendrites, to astrocytes and the systems level).

If you’ve ever wondered how noradrenaline helps shape these multiscale learning processes, you might like this: www.cell.com/trends/cogni...

7 months ago 57 25 3 0

great episode! covered lots of cool territory -- great to see the concept of affordances coming back into the spotlight

7 months ago 0 0 0 0
BI 219 Xaq Pitkow: Principles and Constraints of Cognition
BI 219 Xaq Pitkow: Principles and Constraints of Cognition YouTube video by Brain Inspired
7 months ago 9 3 1 1
Theoretical neuroscience has room to grow - Nature Reviews Neuroscience The goal of theoretical neuroscience is to uncover principles of neural computation through careful design and interpretation of mathematical models. Here, I examine the use of top-down conceptual and...

Theoretical neuroscience has room to grow β€” a Comment article by Ann Kennedy

@antihebbiann.bsky.social

#neuroscience #neuroskyence

www.nature.com/articles/s41...

7 months ago 11 3 2 0

Massive congratulations Annie! Thoroughly well-deserved!!

8 months ago 1 0 0 0

Should have guessed that you would know the precise quote ;)

8 months ago 1 0 2 0
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Neurophysiologist and philosopher Walter Freeman dies at 89 - Berkeley News Pioneering neuroscientist focused on how the brain generates our perception of the world

Haha yep. The son of the lobotomist... news.berkeley.edu/2016/04/27/n...

8 months ago 1 0 0 0
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a cartoon of a man with braces on his teeth says i think we have a winner ALT: a cartoon of a man with braces on his teeth says i think we have a winner

thanks mate! much appreciated

8 months ago 1 0 0 0

@dryohanjohn.bsky.social @drbreaky.bsky.social @christopherjwhyte.bsky.social

8 months ago 3 0 1 0

I need some help from the #neuroskyence Bluesky-verse. Anyone know the source of this ~quote from Walter J. Freeman Jr.: "the secrets of the brain are hidden by two of God’s own firewalls: neurobiology and non-linear dynamics". I read it yrs ago but can't seem to find my way back to the source.

8 months ago 13 4 5 0
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Serotonin drives choice-independent reconfiguration of distributed neural activity Serotonin (5-HT) is a central neuromodulator which is implicated in, amongst other functions, cognitive flexibility. 5-HT is released from the dorsal raphe nucleus (DRN) throughout nearly the entire f...

🚨Pre-print alert🚨

We stimulated serotonin with optogenetics while doing large-scale Neuropixel recordings across the mouse brain. We found strong widespread modulation of neural activity, but no effect on the choices of the mouse 🐭

How is this possible? Strap in! (1/9) πŸ‘‡πŸ§΅

doi.org/10.1101/2025...

8 months ago 92 35 3 1
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🚨 California and Hawaii under tsunami watch after 8.7M quake in Eastern Russia.

8 months ago 1543 575 92 69
Tsunami Warning

Tsunami Warning

Tsunami Warning – 7/30, 9:40am
The Tsunami Advisory has been upgraded to a Tsunami Warning. Waves of up to 3m are expected. Those near coastal areas, rivers, or lakes should evacuate to higher ground immediately. #tsunami

8 months ago 269 149 8 13
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Evolutionary trade-off between vocal tract and testes dimensions in howler monkeys - PubMed Males often face a trade-off between investments in precopulatory and postcopulatory traits [1], particularly when male-male contest competition determines access to mates [2]. To date, studies of pre...

The point is, the monkeys making the loudest noise have the smallest balls.
pubmed.ncbi.nlm.nih.gov/26592343/

8 months ago 29 4 2 0
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Dem leadership should appoint an official Alt Press Secretary to give briefings after every one that Karoline Leavett does and just break them down lie by lie

maybe THAT’S the job we give Colbert πŸ˜‚

8 months ago 1725 312 45 32
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An exciting collaboration is underway. @thetransmitter.bsky.social is partnering with @neuromatch.bsky.social to serve the computational neuroscience community and help connect neuroscientists across all career stages.
www.thetransmitter.org/neuromatch-p...

#neuroskyence

9 months ago 73 22 2 0