I had such a blast sharing my excitement about my favourite organ (the placenta-duh!) at the Pint of Science Graz last night!🍺🧠🔬 Even got to sneak my horse into the slides 😎🐴- how much better can it get?! Thanks so much for having me and for the great turnout 💚 #pintofscienceAT @medunigraz.at

Check Out this cool work from my awesome colleagues and collaborators! ⬇️

Thank you so much for highlighting our work! 🫶

In vitro examination of Piezo1-TRPV4 dynamics: implications for placental endothelial function in normal and preeclamptic pregnancies | American Journal of Physiology-Cell Physiology Mechanosensation is essential for endothelial cell (EC) function, which is compromised in early-onset preeclampsia (EPE), impacting offspring health. The ion channels Piezo-type mechanosensitive ion c...

3/ Why care? Early-onset preeclampsia affects 2–10% of pregnancies and has long-term consequences for both mom & baby. Targeting Piezo1 & TRPV4 might hold therapeutic potential in the future.
Huge thanks to all collaborators @MedUniGraz! Read @AJPCellPhys journals.physiology.org/doi/full/10....

2/ Our findings? In EPE, these channels aren't playing nice. Calcium signaling? Reduced. Nitric oxide production? Complicated. And the endothelial barrier? We’re seeing serious cracks. Turns out, teamwork makes the placenta work—when it's healthy.
#TeamPlacenta #preeclampsia

1/ 🚨more publication news from the lab! Thanks to my FWF funded project we got to look at the Piezo1-TRPV4 duo, 2 ion channels in the placenta that help regulate endothelial function. Spoiler: They're not quite BFFs in early-onset preeclampsia (EPE). Let’s unpack the science!🧬

Exploring the Lifeline: Unpacking the Complexities of Placental Vascular Function in Normal and Preeclamptic Pregnancies The proper development and function of the placenta are essential for the success of pregnancy and the well-being of both the fetus and the mother. Placental vascular function facilitates efficient f....

Beautiful review on the placental vasculature and is known of its altered function in pre-eclampsia by Hanna Allerkamp and colleagues at MedUniGraz👏 onlinelibrary.wiley.com/doi/abs/10.1...

Different internet home - same science 🔬🧪🧫 #TeamPlacenta