Anti-progestin therapy targets hallmarks of breast cancer risk Nature - Results of an early-phase breast cancer prevention trial demonstrate the potential for breast cancer prevention in premenopausal women with anti-progestin therapy by inducing...

Really happy to share a link to our work showing that anti-progestin therapy could help prevent breast cancer before menopause.
Published today in Nature, the study suggests this could be a new way to stop breast cancer before it starts: urldefense.com/v3/__https:/...
Brilliant team science

Contractile fibroblasts form a transient niche for the branching mammary epithelium Nature Communications - Fibroblasts represent a heterogenous cell population but how their differences reflect their plasticity and origin is not fully understood. Here, the authors map the origin...

So proud of the exciting story from my PhD student Jakub Sumbal on contractile fibroblasts shaping branching morphogenesis!
Fantastic collaboration with the lab of Zuzana Koledova in Prague!
@sumbalovakoledova.bsky.social

It just came out online, check it out here:
rdcu.be/eIIKD

Geometry first: how positional cues dictate fate in bilayered epithelia - the Node Behind the paper story focussed on research on early fate decisions in bilayered epithelia.

Geometry first: how positional cues dictate fate in bilayered epithelia thenode.biologists.com/geometry-fir...

Congratulations to the team on all their hard work on developing this first of its kind model! @andreaventura.bsky.social @psalmotoxin.bsky.social @wtklab.bsky.social
@kytsailab.bsky.social @moffittnews.bsky.social

Congratulations too @labrawlins.bsky.social!

Here is a photo of us “not celebrating” from few days ago when we received the email!

Thank you @frelab.bsky.social

Could this be the future of cancer prevention?

Walid Khaled‬, a new ERC Advanced Grant recipient @cam.ac.uk‬, will work on a preventive vaccine for breast cancer.

Learn more 👉 buff.ly/s6cBCwL

#ERCAdG #CancerResearch #FrontierResearch @wtklab.bsky.social‬

Thank you @erc.europa.eu for highlighting PreBRCATx. I am excited where this grant will take will take our science - hopefully a step closer to therapeutic cancer prevention!

Our latest paper from is out! Congratulations to all members the lab that contributed over the years!

No UMAPs in this one!

@phar.cam.ac.uk @scicambridge.bsky.social

Thanks to our funders @cancerresearchuk.org @breastcancernow.bsky.social

Join our Prevention Primer on 24 June and grow your knowledge ahead of @cancerresearchuk.org's #PrevConf25. Hear from Prof Peter Sasieni, @sarahblagden.bsky.social, @wtklab.bsky.social and others, inc lab scientists, clinicians, behavioural scientists and epidemiologists.

Great opportunity in our department 👇👇

www.jobs.cam.ac.uk/job/44592/

Check out the final programme for ENBDC (23-26 April) now with 7 short talks selected from the abstracts.

Last 8 spots still available but you need to be quick! We can accept applications till 31st March.

We are looking for a doctoral candidate to join the lab! If you are interested in working with human breast tissue samples straight from the clinic and do not fear large data sets, this might just be your dream project ☺️ Apply now ⬇️
ats.talentadore.com/apply/vaitos...
📸 @oonapaavolainen.bsky.social

Congrats!

Lab’s latest: (mouse) mums grow their guts during pregnancy and lactation: www.cell.com/cell/fulltex...

Music therapy for those living with dementia Hello everyone! My name is Linsey, and my husband Alan and I are excited to support the Saffron Hall Trust through my fundraising campaign on GivenGain. The Trust uses music therapy for many different...

Linsey Porter in our lab is running the Cambridge half marathon for this worthy cause 👇👇. Please support if you can.

www.givengain.com/project/lins...

JOB ALERT (9 days to go)

We are looking for a computational postdoc to lead on the analysis of the NMGN Ageing Cluster spatial transcriptomics dataset.

Start date: Flexible
Tenure: 3 years
Deadline: 28th Feb 2025

Informal queries welcome!
Please RT

Deadline extended to 28th Feb!

JOB ALERT
We are seeking a Computational Research Assistant or Research Associate to help drive an ambitious multiomics ageing project part of the NMGN Mouse Ageing Cluster.

www.jobs.cam.ac.uk/job/49939/

@scicambridge.bsky.social @phar.cam.ac.uk @cambridgebiosci.bsky.social

An AI generated image showing a naked mole-rat with visceral pain...the tail is coming out of the stomach!

🚨 Excited to announce that we are hiring 🚨

If bowel disease, pain, & naked mole-rats are your thing then we have the perfect opportunity for you 😃

This ChatGPT image shows a naked mole-rat with visceral pain, but they actually appear resistant #PainResearch

Registration is now open for the 16th ENBDC workshop 24-26 April 2025

Great line-up of speakers 👇

6 selected talks from abstracts ✍️

Limited spaces available. Sign up early to avoid disappointment!
enbdc.org/workshop/

We are forming a patient advisory group to help shape our research on BRCA breast cancer prevention! Follow the link/scan the barcode for more info and to express interest. Please share! @wtklab.bsky.social
www.stemcells.cam.ac.uk/about-us/eng...

Plenary Lecture to explore breast cell atlas in cancer prevention, treatment - SABCS Meeting News Walid Khaled, PhD, will deliver the second plenary lecture during the 2024 San Antonio Breast Cancer Symposium® about cell atlases as roadmaps in cancer immunology.

First post on here!

Looking forward to sharing what we learnt over the years from studying the mouse and human breast at the single cell level!
@crukcamcentre.bsky.social
@sabcs.bsky.social
@cancerresearchuk.org

www.sabcsmeetingnews.org/plenary-lect...

The Hallmarks of Precancer Summary:. Research on precancers, as defined as at-risk tissues and early lesions, is of high significance given the effectiveness of early intervention. We discuss the need for risk stratification to...

Earlier this year, we published an article in Cancer Discovery discussing six hallmarks of precancer and highlighting the need for a multi-omics approach to research in this area. aacrjournals.org/cancerdiscov...

Would love to connect with others working in this area!