Beautiful castle, thx for sharing!

A study using an n=1 experiment with single standards at 0V CID reported that 70% of detected ions were in-source fragments (ISFs). www.nature.com/articles/s42... This finding was extrapolated to suggest that ISFs affect all metabolomics experiments to this degree. A counterpoint. rdcu.be/ebFwc 1/n

Discovery of anti-inflammatory molecules from Dendrobium officinale based on activity labelled molecular networking and its alleviation effect on ulcerative colitis The present study aimed to discover anti-inflammatory molecules from Dendrobium officinale using mass spectrometry-based molecular networking technolo…

Discovery of anti-inflammatory molecules from Dendrobium officinale based on activity labelled molecular networking and its alleviation effect on ulcerative colitis #FRI #MassSpec www.sciencedirect.com/science/arti...

Discovery of metabolites prevails amid in-source fragmentation - Nature Metabolism Nature Metabolism - Discovery of metabolites prevails amid in-source fragmentation

I'm happy to share a correspondence in @naturemetabolism.bsky.social in which I was involved. #metabolomics #lipidomics www.nature.com/articles/s42...

Unlocking hidden treasures: the evolution of high-throughput mass spectrometry in screening for cryptic natural products Covering: 1994 to 2024Historically, microbial natural product discovery has been predominantly guided by biological activity from crude microbial extracts with metabolite characterization proceeding o...

Unlocking hidden treasures: the evolution of high-throughput mass spectrometry in screening for cryptic natural products

Brett Covington & Mohammad Seyedsayamdost

@natprodreports.bsky.social

pubs.rsc.org/en/content/a...

Such great use of feature based molecular networking and spatial analysis how geography affects growth.

Nice pics 👏🏻