Spring, Knowlton, Que.
Prudence Heward
1942

Podcast promo: "Leaping Forward Into... What? An Interview With Dr Robert... JAMA+ AI Conversations." The cover image shows a man wearing a lab coat and glasses with a circuit board background.

Robert Wachter, MD, spoke with JAMA+ AI Editor-in-Chief Roy Perlis, MD, MSc, about how #GenerativeAI tools are already ubiquitous among trainees and clinicians and what's next for digital platforms in #medicine.

🎧 Listen now:
ja.ma/3QhB0ao

Re: that last post from Propter. I wrote 25k lines of code with Claude Code last month.

Is it good code? I don’t know.

Does it do what I need it to a make me better at my job? Yes, absolutely.

Would it ever have gotten written without Claude Code? Absolutely tf not.

Gorgeous sunset colors over Point Reyes tonight.

To accompany my textbook (Computational Foundations of Cognitive Neuroscience) and the class I taught this semester, I'm open-sourcing my lectures slides:
gershmanlab.com/lectures.html
I'll continue to update these as I improve them.

After 'unprecedented' results, SF researchers get closer to HIV cure "We haven't quite made it to the promised land. We're getting close."

A UCSF trial aims to retrain HIV patients' immune systems to keep the virus at bay w/o meds & has shown promising results, with several patients remaining virus-free for months. “We haven’t quite made it to the promised land," Dr. Steven Deeks says. "We’re getting close.” https://ucsfh.org/4cqO4S1

That's right. Inflammation is the big miss for getting ahead of coronary artery disease
scientificamerican.com/article/new-...
My review of this big shift
erictopol.substack.com/p/the-big-sh...

EXCERPTS FROM KAFKA'S DIARIES 281 JANUARY 20. The end of writing. When will it take me up again? JANUARY 29. Again tried to write, virtually useless. JANUARY 30. The old incapacity. Interrupted my writing for barely ten days and already cast out. Once again prodigious efforts stand before me. You have to dive down, as it were, and sink more rapidly than that which sinks in advance of you. FEBRUARY 7. Complete standstill. Unending torments. MARCH 11. How time flies; another ten days and I have chieved nothing. It doesn't come off. A page now anc hen is successful, but I can't keep it up, the next day m powerless. MARCH 13. [.] Lack of appetite, fear of getting ba te in the evening; but above all the thought that I wr

The writing life, courtesy of Franz Kafka.

also been to both...Oracle for sure...Camden is nice though

You should turn off message content in your notification settings. No real point in using an end to end encrypted app if people can just read the push notification.

The fog sucked into West Marin tonight but stayed below the sunset over Point Reyes making for some breathtaking views.

The Moon Waited Too
Billie Rae Busby
2025

No Egrets
Heidi Holloway
c. 2026

New post, on how to make accurate digital twins. Well, sort of… kucharski.substack.com/p/how-i-made...

Square Dance
Jane Waterous
2024

Happy Opening Day, Part I!

This hurts.

A Tuesday Point Reyes sunset break for a weary world.

Ted in Orange Reimagined
Joe Coffey
2025

interesting submission options for searches

Google Has a Secret Reference Desk. Here's How to Use It. 40 Google features to find exactly what you need, the alternative search engines that do things Google won't, and the reference desk framework underneath all of it.

I know this has circulated with alacrity recently, so you may have already seen it, but if you haven't... WOW BOY HOWDY it's the most useful thing.

Thank you cardcatalogforlife.substack.com -- this is a very very very helpful public service:

cardcatalogforlife.substack.com/p/google-has...

Passage
Fabian Jean
2025

AI and the PhD student: friend or foe? Nature - Graduate students increasingly use artificial-intelligence tools to draft, code and search — but many fear it could erode the very skills a doctorate is meant to build.

Graduate students increasingly use artificial-intelligence tools to draft, code and search — but many fear it could erode the very skills a doctorate is meant to build

go.nature.com/3NMvhbE

#statstab #510 A Note on Dropping Experimental Subjects who Fail a Manipulation Check

Thoughts: Another paper to consider when "removing participants who failed our manipulation check"🤷‍♂️

#manipulationcheck #estimand #experiment #design #bias #guide #assumptions #missingdata

doi.org/10.1017/pan....

If you've had a kidney stone, you've been advised that the most important thing to prevent another bout is to increase hydration. Now a randomized trial of hydration in over 1600 participants showed no benefit, despite evidence of increase during volume. www.thelancet.com/journals/lan...

this is a good piece

I remember having an epiphany at a Census Bureau stakeholder meeting that united business and academics: Scientists use jargon to condense complicated concepts; business people use jargon to inflate simple ones.

Why do women account for nearly 2/3rd of all cases of Alzheimer's disease? A new, thorough review, open-access, on its origins in midlife.
@jci.org
www.jci.org/articles/vie...

The VIF Score. What is it Good For? Absolutely Nothing - Arturs Kalnins, Kendall Praitis Hill, 2025 Variance inflation factors (VIF scores) are regression diagnostics commonly invoked throughout the social sciences. Researchers typically take the perspective t...

#statstab #506 The VIF Score. What is it Good For? Absolutely Nothing

Thoughts: Maybe we need to think more closely about what these metrics mean.

#diagnostics #assumptions #regression #vif #variance #variableselection #error #multicolinearity

journals.sagepub.com/doi/abs/10.1...