Research links tinnitus with serotonin Neurotransmitter known for relieving depression could have opposite effect on tinnitus.

"Researchers with Oregon Health & Science University [Laurence Trussell, former grantee] and Anhui University in China found in a mouse model that elevated levels of the neurotransmitter serotonin in the brain also resulted in elevated behavioral symptoms of tinnitus." news.ohsu.edu/2026/04/20/r...

Woohoo!

Can you observe the analog signaling phenomenon at this synapse

Mossy fibers!

Tune it at 1 pm EDT to EARS early career panel! pennmedicine.zoom.us/j/96672201477

Hey man, I took a quick look at this yesterday. Very impressive! Excited to dive deeper into it. Congrats to the team!

Congrats Ruth Anne!!

REM-sleep twitching in adults and the maintenance of specialized sensorimotor systems Blumberg et al. present video evidence of twitching during adult sleep in a diverse sample of animals. Adult twitching appears to selectively involve appendages used for active sensing, mirroring thei...

New paper (with lots of cute animal videos!)

Ever watch your dog "run" while asleep and wonder what’s going on in their brain? In Current Bio we suggest that those twitches aren't just leaky dreams—they’re a vital maintenance system for the most precise movements

www.cell.com/current-biol...

A major carrot for study section permanence is gone. How then to get quality peer review? The stick?

Is this movie from 2p? This is really nice SNR

Spontaneous inhibitory synaptic currents mediated by a G protein-coupled receptor - PubMed G protein-coupled receptors (GPCRs) affect many physiological processes by modulating both intrinsic membrane conductances and synaptic transmission. This study describes spontaneous miniature inhibitory postsynaptic currents mediated by vesicular dopamine release acting locally on metabotropic D2 r …

Stephanie Gantz and John Williams suggested spatially precise neuromodulator release in DA neurons as well

pubmed.ncbi.nlm.nih.gov/23764286/

Workforce Pay Increases - CUPA-HR This is the public version of this data. CUPA-HR is the most comprehensive, accurate, and up-to-date source of higher education workforce salary data, collected separately for administrators, faculty,...

Staff and administrators saw one final year of pay raises exceeding inflation this year, but that won't happen again for a while.

Tenure-line faculty have had raises below inflation every year for the past decade. Tenure and promotion boosts are often modest (3-10%), and only happen twice.

Matt this is seriously awesome. Some of the stuff you posted reminds me of the second side of Laraaji’s Celestial Vibration.

Gonna try this on our multi neuron calcium traces to drive a bank of arpeggiators

David showed me some of these data about a year ago and all I could respond was “how does it feel to be right?”

A milestone in the quest to find synapse-level explanations for brain function and behavior.

🎻✨ Excited to share my journey from music to auditory research at "Beer, Brain, and Arts!" during Brain Awareness Week. Join us tomorrow at the @hetnatuurhistrdam.bsky.social, or a lab tour at Erasmus MC @erasmusmc.bsky.social !
🔗 www.brain-awareness-week-euc.nl

#BrainAwarenessWeek #Neuroscience

Excited to share some new work from my lab, where we rigorously characterize differences between L5 and L6b extratelencephalic neurons in the auditory cortex!

Philly has a Rocky statue, NOLA’s got one of Ignatius Reilly. Only fair Delta City honor a notorious fictional denizen as well. Very happy this statue finally found a home after years of deliberation.

NMDA receptor-dependent presynaptic homeostatic plasticity? www.biorxiv.org/content/10.64898/2026.02...

Thank you Aaron. Hope all is well

Thanks Kameron. I’ll be in New England over the summer for GRC and BIE. Hope to catch up. Cheers

If you want to work on this or other cool projects like how the auditory system implements RL-like plasticity mechanisms, please get in touch

Thank you NIDCD for supporting our work on learning-related plasticity in mammalian sound localization circuits.

Call it #ExplainableAI or just making sense of complexity. We establish a direct link between DNNs fit to #AuditoryCortex and more intuitive subspace models from the 2000s. Congrats @jeremewingert.bsky.social @satyaparida.bsky.social & Sam Norman-Haignere! #NeuroAI #SensoryNeuroscience rdcu.be/e5gLY

Reminds me of Philip K Dick’s UBIK

🚀 New preprint from the lab! Our first foray into the subiculum uses in vivo whole-cell recordings to show that dendritic plateaus are a prominent, learning-dependent signaling mode of subicular neurons. Feedback is welcome!

www.biorxiv.org/content/10.6...

Whoa cool

Looks awesome! Congrats Weinan and team!!

Duration between rewards controls the rate of behavioral and dopaminergic learning - Nature Neuroscience Cue–reward learning rate scales proportionally with the time between rewards. Consequently, learning over a fixed duration is independent of the number of trials. This challenges trial-based dopamine ...

Big if true. Anyone know if human learning curves are also (mostly) trial count independent?

www.nature.com/articles/s41...

Water-mediated hydrogen bonds and local side-chain interactions in the cooperative collapse and expansion of PNIPAM oligomers | PNAS Poly(N-isopropylacrylamide) (PNIPAM), a thermoresponsive homopolymer, is a well-established model for investigating coil-to-globule transitions. He...

Excited to share results from our new PNAS paper. We studied PNIPAM—a shape-shifting polymer that collapses from an extended coil to a compact globule near body temperature — making it a prime candidate for drug delivery systems and soft robotics.

Ok, ok, hear me out. What happens when you make the human-owl hybrids wear prism goggles?!