What are Bayesian logic and Bayesian statistics? And how do they help to run the modern world? Sir David Spiegelhalter, Emeritus Professor of Statistics at the University of Cambridge, explains all. Made in partnership with #BBCIdeas. https://www.youtube.com/watch?v=-pnlExzbNqE
Excited to announce the release of The Human Genotype-Phenotype Map!
* We processed 16k complex traits & 2.7M QTLs
* Turned 49.3M significant colocalizations into 97k distinct groups
* Upload your own GWAS to compare against all data
Website: gpmap.opengwas.io
Preprint: tinyurl.com/3ktsr9hw
Great review on The Genetics of Human Handedness: Microtubules and Beyond www.cell.com/trends/genet... - handedness is such an interesting phenotype!
Genetics of human handedness: microtubules and beyond
Genetics of human handedness: microtubules and beyond. Check out this review by @ocklenburg.bsky.social published in @cp-trendsgenetics.bsky.social http://dlvr.it/TNjZCR #ASHG25
The love of reading is an endangered species.
Just 16% of Americans do regular leisure reading—down from 28% in 2003. Only 41% of UK parents read daily to their toddlers—down from 64% in 2012.
Books aren't merely a source of flow. They're a gateway to empathy and lifelong learning.
Multiple headlines about the first CRISPR 2.0 personalized genome editing and photo of the baby treated
This week's genome editing triumph is a big deal.
Here's why
erictopol.substack.com/p/the-first-...
Looking forward to this coming out soon. In the paper, we propose a hierarchy for how different psychological constructs affect behaviour in athlete development contexts.
The genetic basis of human height www.nature.com/articles/s41... (read free: rdcu.be/egGQf) 🧬🖥️🧪
You’re welcome…
Psychological insights for judging expertise and implications for adversarial legal contexts
Review by Kristy A. Martire, Tess M. S. Neal, Fernand Gobet, Jason M. Chin, Jonathan F. Berengut & Gary Edmond
Web: go.nature.com/4ig3zhE
PDF: rdcu.be/edUS3
#psychology #psychscisky
Nice work, Ben!
I think that this paper is not cited enough.
If you use p-values in your research, and you can't do otherwise, it would be desirable to at least quantify what is the false discovery rate for your sample size and chosen thresholds. It'd be surprising. 🧪
royalsocietypublishing.org/doi/10.1098/...
Great day at the MIT Sports Summit connecting with sports industry leaders and tech professionals.
Just published!
"The problems with genetic essentialism, determinism, and reductionism."
karger.com/hde/article-...
Reminder that LOIs are due at the end of the month.
I feel like I'm getting predictable... In my defense, there is no better way to spend a week in February. #SpringTraining
Full-on eugenics, in its most rabid, racist form is oozing its way back into mainstream discourse.
Excited for this one to get out. Led by the amazing Jesse Korf. Coming soon!!
A tree can afford a human the actions of swinging from a branch, sheltering from the rain, or escaping a dangerous animal. Credit: Stephen T. Asma and Rami Gabriel. https://philosophyofbrains.com/2020/02/18/affordances-and-motivation.aspx
James Gibson was born OTD in 1904.
His concept of the “affordance” dissolved the dichotomy between the organism and their environment. Each organism experiences its own environment: as things it can do or use, or barriers to its action or use.
🌱🐋 🦫🦋🧪🌎#philsci #psychsky #histSTM
How population stratification makes environments look like genes. A short 🧵:
The Genomic Code: The genome instantiates a generative model of the organism arxiv.org/abs/2407.15908 (revised version, following peer review)
New blog post: “Heritability: Five battles”. It’s a (very) long and opinionated but hopefully beginner-friendly discussion, structured around five contexts in which people study and argue about heritability. (1/7) www.lesswrong.com/posts/xXtDCe...
Does effort make life more meaningful? Was Sisyphus living the dream? In our new paper (now accepted in Cognition!), across 6 studies with nearly 3,000 participants, we found that more effortful tasks feel more meaningful 🧵
"“Let’s edit your baby’s genome and hope for the best” is not exactly a compelling marketing slogan. It’s certainly not a responsible medical attitude."
This is a typically first-class analysis from @wiringthebrain.bsky.social.
www.wiringthebrain.com/2025/01/euge...
Diagram of H.M.S. Beagle, from Journal of Researches into the Natural History and Geology of the Various Countries Visited by H.M.S. Beagle, etc. (1890). Poop cabin is aft. Credit: Darwin Online.
OTD in 1831, HMS Beagle set sail from Falmouth on a cartographic mission in the service of British imperial and commercial interests.
On board as a supernumerary companion to the captain was a recent Cambridge graduate named Charles Darwin. He worked in the poop cabin.
#HistSTM #HPBio 🧪 #EvoBio
MLB found days spent on the injured list by pitchers increased from 13,666 in 2005 to 32,257 in 2024. The study asserts that the pursuit of velocity and max-effort pitching are the "primary forces driving the long-term increase in pitcher injuries." thescore.com/mlb/news/316...
abstract of a scientific paper
Developmental noise is an overlooked contributor to innate variation in psychological traits pubmed.ncbi.nlm.nih.gov/36098433/ - just because the variation is not all genetic in origin, doesn't mean the rest is necessarily "environmental"
The tech bro fascination with eugenics is so on brand. The idea that you could make accurate, actionable predictions from individual genotypes (with all their complex, non-linear interactions) from averaged, linearly modeled population-level genomic statistics is just another big data fantasy