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Posts by Sander Smits

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History in the making! 🎓 Huge congratulations to Nora Zöllner, who successfully defended her PhD - earning top honors!
Nora is the very first graduate of our MibiNext cohort. We couldn’t be prouder! A massive achievement for her and a major milestone for the entire network.

#MibiNet #MibiNext

1 week ago 5 5 0 0
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Standing ovations for an incredible Maya Schuldiner, who just received the Otto Warburg Metal at the #MosbacherKolloqium of the @gbmev.bsky.social and delivered the most impressive, passionate speeches one can imagine... beautiful oration by Christian Ungermann and many tears in the lecture hall 🧪💕

3 weeks ago 19 5 0 1
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This year‘s Lynen Lecture was held by Bruno Antonny (Valbonne, France). Robert Ernst gave the laudatio for Bruno‘s scientific achievements.

3 weeks ago 11 3 0 0
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Dissecting the RNA-binding capacity of the multi-RRM protein Rrm4 essential for endosomal mRNA transport Abstract. RNA-binding proteins (RBPs) utilize multiple RNA-binding domains (RBDs) to engage with extensive messenger RNA (mRNA) networks. Understanding the

Breakthrough article 😊
Joint effort of teams Zarnack & König & Feldbrügge clarifies how multiple RNA-binding domains cooperate to identify functional important binding sites in vivo
doi.org/10.1093/nar/...
@zarnack-group.bsky.social
@könig-lab.bsky.social
@mibinet.bsky.social
#EMBOrnaLocalization

2 weeks ago 25 16 1 1
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First conference of the newly founded interfaculty Center of Membrane Research at HHU. Two days of exciting talks about all areas of membrane research. Thanks to all speakers and participants for a great time. For sure worth to be repeated!

2 weeks ago 12 4 1 0

@spp2330.bsky.social

1 month ago 2 1 1 0

Thanks for highlighting our work done at @hhu.de @chemiehhu.bsky.social published in @angewandtechemie.bsky.social , Aubrey @aubreyzerkle.bsky.social! Rare earth elements rock! doi.org/10.1002/anie...

1 month ago 15 4 1 0
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A protein adaptor mediating Ap4A-dependent control of protein acetylation - Nature Communications This study identifies AcuB as a conserved inhibitor of the deacetylase AcuC in bacteria. AcuB directly suppresses AcuC activity, and this inhibition is enhanced the alarmone diadenosine tetraphosphate...

AP4A functions as a regulatory switch of protein acetylation, connecting stress signaling to central metabolism.

@synmikro.bsky.social @unimarburg.bsky.social @mpimicrobiomarburg.bsky.social

Enjoy the reading:

www.nature.com/articles/s41...

1 month ago 10 3 0 0
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Lasse presents our CRC1535 MibiNet project at the first RNA confluence meeting at the EMBL.
@rhinelandrna.bsky.social @mibinet.bsky.social

2 months ago 7 3 0 0
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Please RT:
Looking forward to our International Symposium on "Microbial Networking - from organelles to cross-kingdom communities".
Highlight of our first funding period of our Collaborative Researc Center @mibinet.bsky.social, @dfg.de

www.sfb1535.hhu.de/mibinet

@hhu.de , @fz-juelich.de

2 months ago 10 9 1 0
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Super happy to share that our Chemical Science article ‘Structural control of dynamic covalent cages: kinetic vs. thermodynamic assembly and PFAS removal from water’ (pubs.rsc.org/doi/D5SC02247A) has been selected for the 2025 most popular supramolecular articles collection 🎉

2 months ago 5 2 0 0

Happy to announce that our review article on vesicle-coupled mRNA trafficking is now availalbe

@mibinet.bsky.social

#EMBOrnaLocalization

link.springer.com/article/10.1...

2 months ago 13 8 0 0

@mibinet.bsky.social

3 months ago 0 0 0 0
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Strukturanalyse: Veröffentlichung in ACS Sensors Um Stoffwechselprozesse zu verstehen, ist es wichtig, einzelne wichtige Elemente in lebenden Organismen nachweisen zu können. Forschenden der Heinrich-Heine-Universität Düsseldorf (HHU) entwickelten n...

I feel very grateful that our recent publication on rapid biosensor creation has been announced by HHU (Heinrich Heine University Düsseldorf). 🍀🙏🏼🤩🧪🦠🧫🔬

www.hhu.de/news-einzela...

3 months ago 2 1 1 0
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A Novel Biosensor for Ferrous Iron Developed via CoBiSe: A Computational Method for Rapid Biosensor Design Genetically encoded biosensors enable the monitoring of metabolite dynamics in living organisms. We present CoBiSe, a computational biosensor design approach using Constraint Network Analysis to ident...

✨ I am thrilled to share ✨ that our paper on computational biosensor design has just been published!

Huge thanks to all co-authors and collaborators for the great teamwork and dedication throughout this journey! 🙌

📄 Read the paper here:
pubs.acs.org/doi/10.1021/...

3 months ago 4 3 0 0
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A Novel Biosensor for Ferrous Iron Developed via CoBiSe: A Computational Method for Rapid Biosensor Design Genetically encoded biosensors enable the monitoring of metabolite dynamics in living organisms. We present CoBiSe, a computational biosensor design approach using Constraint Network Analysis to ident...

We Are very happy that our Paper was published. Thank to everyone involved

pubs.acs.org/doi/10.1021/...

@mibinet.bsky.social @mfeldbruegge.bsky.social @frunzkelab.bsky.social

3 months ago 10 8 1 0

🔬 Job Alert! 🚨

Goethe University Frankfurt is hiring a Head of our new Imaging Facility at Campus Riedberg!

Lead and support a vibrant imaging community, working with cutting-edge microscopes, e.g. a new Zeiss LSM 980, a Z1 Light Sheet, and a new Leica Stellaris.

gerbi-gmb.de/resources/ca...

3 months ago 2 2 0 0
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Abteilungsleitung (m/w/d) Forschungsmanagement und Transfer - Heinrich-Heine-Universität Düsseldorf Heinrich-Heine-Universität Düsseldorf bietet Stelle als Abteilungsleitung (m/w/d) Forschungsmanagement und Transfer in Düsseldorf - jetzt bewerben!

Werde Teil des Teams @hhu.de:
#Stellenangebot, scheinbar unbefristet. Grüße an #ichbinHanna & #ichbinReyhan

4 months ago 10 4 0 0

@mfeldbruegge.bsky.social @mibinet.bsky.social

4 months ago 0 0 0 0
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Vesicle-coupled mRNA transport and translation govern intracellular organelle networking - EMBO Reports Eukaryotic cells are highly compartmentalized, enabling sophisticated division of labour. For example, genetic information is stored in the nucleus while energy is produced in mitochondria. Despite th...

Very happy to See This Published!!!! Thanks for the collaboration

link.springer.com/article/10.1...

4 months ago 11 6 1 1
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Vesicle-coupled mRNA transport and translation govern intracellular organelle networking - EMBO Reports Eukaryotic cells are highly compartmentalized, enabling sophisticated division of labour. For example, genetic information is stored in the nucleus while energy is produced in mitochondria. Despite th...

Very happy to See This Published!!!! Thanks for the collaboration

link.springer.com/article/10.1...

4 months ago 11 6 1 1
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Finally out – It is all about cholesterol
Thanks to all for this excellent collaboration

4 months ago 4 3 0 0
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Postdoc (m/f/d) in Endosymbiosis Research

📢Postdoc position available!🧪🧫🧬
Our group is seeking a motivated researcher to investigate the molecular mechanisms driving host–endosymbiont interactions.
Full details & application: karriere.hhu.de//index.php?a....
Please help us get the word out!

4 months ago 24 35 0 0
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DFG fördert Projekte für ressourceneffizientere Großgerätenutzung in der Forschung

Die DFG fördert Projekte für ressourceneffizientere Großgerätenutzung in der Forschung mit insgesamt ca. 5,5 Mio €. Außerdem werden zusammen mit der GWK bis Ende 2025 Anträge unter dem üblichen Schwellenwert möglich, die eine längere Nutzung vorhandener Geräte erlauben.
Details: sohub.io/r4km

5 months ago 10 4 0 0
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crTP X-ray structure

crTP X-ray structure

✨X-ray crystallography reveals surprising twist in how proteins enter the unique photosynthetic organelles of Paulinella. The chromatophore targeting peptide (crTP) folds into a 3D structure, hinting that folded proteins cross peptidoglycan and inner membrane. (1/2)
academic.oup.com/plphys/artic...

5 months ago 26 10 3 1
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New publication in J Mol Biol
New insights in to the function of the CLD and the entire hemolysin secretion machinery. Thanks to Holger Gohlke’s lab and CSS for the wonderful collaboration. Congrats to Sakshi and Cigdem!

5 months ago 6 2 0 0
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Hijacking a bacterial ABC transporter for genetic code expansion - Nature Bacterial ATP-binding cassette (ABC) transporters can be utilized and engineered to transport non-canonical amino acids into Escherichia coli for highly efficient synthesis of proteins with novel func...

🚨Our paper is out! 🥳
Hijacking a bacterial ABC transporter for efficient genetic code expansion.
Many congrats to everyone involved - a multi-year effort led by @taruniype.bsky.social @maxfottner.bsky.social
www.nature.com/articles/s41...

it all started years ago with a failed experiment
🧵👇 1/9

6 months ago 214 60 20 14
Junior Group Leader - Phage Biology & Biotechnology As a leading research institution for microbial biotechnology the Institute of Bio- and Geosciences - Biotechnology (IBG-1, https://www.fz-juelich.de/de/ibg/ibg-1 ) at the Forschungszentrum Jülich foc...

Please RT:
We have an opening for a junior group leader position in „Phage Biology & Biotechnology“.
www.fz-juelich.de/de/karriere/...

Interested candidates are encouraged to contact me via email for further details.

@spp2330.bsky.social; @mibinet.bsky.social

6 months ago 35 57 0 1

Excited to share our latest work, spearheaded by @gabmrojas.bsky.social!

GPCRs are central sensors in eukaryotes, but little is known about them in fungi. In Ustilago maydis, we now uncovered a host-dependent GPCR mechanism that promotes fungal infection.

Gabriel nicely explains the full story👇

6 months ago 7 2 0 0
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Evolutionary refinement of mitochondrial and plastid targeting sequences coincides with the late diversification of land plants Abstract. Plastids and mitochondria are key to plant survival and adaptation. The evolutionary progress of land plants (embryophytes) witnessed gene and ge

The evolution of land plants involved a charge-based adaption in the targeting sequences for #mitochondria and #chloroplasts and the origin of their de/phosphorylation.

#science 🧪

academic.oup.com/mbe/advance-...

6 months ago 7 2 1 0