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More here: arabsinneuro.org/school/
Posts by Mohamady El-Gaby
The world watched as Israel razed Gaza to the ground.
Now, the world is watching as Israel razes Lebanon to the ground.
War crimes beget war crimes — and the failure to bring Israel to justice for genocide has emboldened it to destroy human life with total impunity.
Academic friends,
It's beyond heartbreaking to watch what's unfolding in Iran & the region.
A few of us drafted an open letter calling for protection of civilians & of educational, research, medical & cultural institutions.
Please read & sign if you agree:
sites.google.com/view/protect...
#IranWar
If racism was a country: www.bbc.co.uk/news/article...
“In addition, the return of more than 600,000 residents of southern Lebanon who evacuated northward will be completely prohibited south of the Litani until the safety and security of northern (Israeli) residents are ensured”
Graphical abstract showing that NMDAR immunisation drives psychosis-like behaviour in mice, while clozapine reverses this. Upper panel: arrows show NMDAR immunisation producing a mouse exhibiting psychosis-like behaviour, with clozapine reversing this effect. Lower panels: anti-NMDAR antibodies bind neuronal NMDA receptors, which are then eliminated by microglia via phagocytosis, leading to psychosis. Clozapine restores NMDA receptor levels by reducing anti-NMDAR antibody levels, consistent with an immunomodulatory mechanism of action.
🥁🎉The Psychosis Collective proudly presents our first preprint
𝐂𝐥𝐨𝐳𝐚𝐩𝐢𝐧𝐞 𝐬𝐮𝐩𝐩𝐫𝐞𝐬𝐬𝐞𝐬 𝐚𝐮𝐭𝐨𝐢𝐦𝐦𝐮𝐧𝐢𝐭𝐲 𝐝𝐫𝐢𝐯𝐢𝐧𝐠 𝐩𝐬𝐲𝐜𝐡𝐨𝐬𝐢𝐬-𝐥𝐢𝐤𝐞 𝐛𝐞𝐡𝐚𝐯𝐢𝐨𝐮𝐫 𝐢𝐧 𝐦𝐢𝐜𝐞
𝘈 𝘥𝘪𝘴𝘤𝘰𝘷𝘦𝘳𝘺 𝘫𝘰𝘶𝘳𝘯𝘦𝘺 𝘪𝘯 𝘵𝘩𝘳𝘦𝘦 𝘢𝘤𝘵𝘴
starring Le He & Harriet Feldman
www.biorxiv.org/content/10.6...
We wanted to understand how antipsychotics work. Thread🧵
1/n
With Cosyne around the corner, I thought I would:
a) make a thread about our “A cognitive map for value-guided choice in the vmPFC” Cell paper (i'm a bit late). shorturl.at/DBA3H
It's Cosyne time!!
Here are some contributions from my lab and some of my close collaborator labs (Thomas Akam, @melgaby.bsky.social, Steve Kennerley, @sameershethmd.bsky.social )
At #cosyne2026? Check out Sumedha Nalluru’s poster from our lab! Showing that reduced cortical inhibition causes false associations. Friday 13th March from 1:15 - 4:15pm.
Looking forward to :)
This is a game changer. Even structures as complex as a torus can be innate.
All of these posters feature nods to a framework we call duplicated structured representations (DSRs) that seems to unify a broad swathe of PFC data and make cool new predictions. Watch this and @kristorpjensen.bsky.social ‘s space for more on this over the coming year! 6/6
@mathiassablemeyer.bsky.social is taking these ideas one step further and showing how a hierarchical structure can be encoded in MEG activity from humans performing nested sequences. This work elegantly rules in/out different models of hierarchical coding! 5/6
I also want to highlight awesome work from friends in the Behrens lab. @skuechenhoff.bsky.social is finding both fMRI and single unit evidence for two different ways of encoding task progress in the human PFC and MTL! 4/6
Mingyu is asking how these goal progress signals come about in the first place. Turns out ventral hippocampus and PFC interactions might be critical for this. A tour de force of simultaneous hippocampus-PFC neuropixels recordings and optogenetic silencing! 3/6
Adam will show how neurons in the mouse PFC, and both medial and lateral Entorhinal cortices compare when it comes to encoding goal and task progress and how this relates to space and time. Featuring 100s of simultaneously recorded LEC neurons! 2/6
First Cosyne for the Mind Mechanisms lab!
We’re broadly interested in world and goal models in the PFC and temporal lobe. Come chat to @adamloydharris.bsky.social and Mingyu Zhu as they present some new findings tomorrow (Thursday) evening. #Cosyne2026 …🧵 1/6
Excited to see this Version Of Record of my work out in @elife.bsky.social!
elifesciences.org/articles/106...
We investigate the mental representation of geometric shapes in adults and children using fMRI and MEG. Each figure has a video of me explaining the figure: go and read it, or read below.
With this one in print, I think I finally earned that PhD... 😅
Presented for the first time at the cosyne when the world ended (March 2020). I'll bring over a summary thread from twitter when it was still twitter...
www.sciencedirect.com/science/arti...
A must read for anyone interested in the social brain.
We review studies showing that when brain areas face similar computational demands in social and non-social context, they perform the same computations. We argue that exaptation (repurposing of traits for new functions) played a key role in brain evolution.
Thrilled to finally share this work! 🧠🔊
Using a new reinforcement-free task we show mice (like humans) extract abstract structure from sound (unsupervised) & dCA1 is causally required by building factorised, orthogonal subspaces of abstract rules.
Led by Dammy Onih!
www.biorxiv.org/content/10.6...
Cosyne Viewing Parties
Visas, costs, care responsibilities, and environmental concerns all limit Cosyne attendance. Luckily, the talks are livestreamed; but watching alone is the high road to an aneurism. Hence: viewing parties! Gather regionally to watch Cosyne talks! More info: shorturl.at/3DHZX.
Hybrid neural–cognitive models reveal how memory shapes human reward learning
www.nature.com/articles/s41...
New discovery! Value-based decisions reorganize neural state space. Options are first encoded in orthogonal subspaces Then the selected option rotates into a "readout subspace".
Neural subspace reorganization reflects value-based decision making.
www.biorxiv.org/content/10.6...
#neuroscience
*Multi-region computations in the brain*
When two regions are better than one...
doi.org/10.1016/j.ne...
#neuroskyence
It’s PhD defence season. Here is a short guide on how to ace these.
The hippocampus is not a library, it is a simulation engine.
HPC is known for storing maps of the environment but not so known for generating planned trajectories.
This paper proposes that recurrence in CA3 is crucial for planning.
A🧵with my toy model and notes:
#neuroskyence #compneuro #NeuroAI
Do you need your toes to think?
YESS!
Happy to see this one out 😎!
From your humble toes to your noble neurons, you need all your cells to solve your most important problem :
How to stay alive 😎😅
Elena Gutierrez , @sandra-neuro.bsky.social and @mathiassablemeyer.bsky.social
If you attended our SfN symposium on cognitive maps in the PFC then here’s a recap of what was covered. If you didn’t then here’s what you missed! TLDR: converging evidence for structured representations of the world and task in the PFC in humans NHPs and rodents. Led by @sebves.bsky.social and…