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Posts by Jack Hruska, Ph.D.

Figure in the main study showing the migration route and diurnal locomotion along their migratory journey

Figure in the main study showing the migration route and diurnal locomotion along their migratory journey

Small migratory birds cross deserts and seas as part of their annual migration. But how?

Our new study shows how thrush nightingales do it: by flying night after night and stopping during the day, when they remain innactive🐦➡️(1/3)
doi.org/10.1098/rsbl...

@royalsocietypublishing.org
#BirdMigration

5 hours ago 28 19 4 2
DNAharvester's workflow.

DNAharvester's workflow.

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We present DNAharvester 🎉🦴🚜🧬

A pipeline to process highly degraded ancient DNA data that integrates metagenomic filtering, competitive mapping, multiple alignment strategies, reference bias evaluation and much more.

GitHub: github.com/NBISweden/DN...

Preprint: www.biorxiv.org/content/10.6...

1 day ago 42 22 0 1
Screenshot of a tweet by Rep. Ro Khanna (@RoKhanna) praising a breakthrough in pancreatic cancer research, calling it "the best of America" and noting that lead researcher Dr. Balachandran is the son of Indian immigrants and works at Sloan Kettering. He quote-tweets Ian Weissman, DO (@DrIanWeiss...), who reports that an mRNA pancreatic cancer vaccine showed lasting results in an early trial, with nearly all responding patients still alive six years later.

Screenshot of a tweet by Rep. Ro Khanna (@RoKhanna) praising a breakthrough in pancreatic cancer research, calling it "the best of America" and noting that lead researcher Dr. Balachandran is the son of Indian immigrants and works at Sloan Kettering. He quote-tweets Ian Weissman, DO (@DrIanWeiss...), who reports that an mRNA pancreatic cancer vaccine showed lasting results in an early trial, with nearly all responding patients still alive six years later.

Science leads to amazing breakthroughs. Immigrants lead to amazing science.

1 day ago 3209 707 86 28
Map of the contiguous United States showing the spring bloom index anomaly as of April 19, 2026 from the USA National Phenology Network. Many areas are earlier than normal.

Map of the contiguous United States showing the spring bloom index anomaly as of April 19, 2026 from the USA National Phenology Network. Many areas are earlier than normal.

Aside from Florida, nearly the entire contiguous U.S. has experienced earlier than average first plant blooms in 2026. Earlier springs can cause longer allergy seasons, accelerate wildfire risk, increase pests/mosquitoes, and lead to less reliable snow-fed water.

Map: www.usanpn.org/data/maps/sp...

2 days ago 226 105 10 7
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Unfalsifiable by Design: A Year of Trying and Failing to Reproduce a Human Microbiome and Autism Study The myth of open data, reproducibility, responsibility, and accountability in science, and your role in it

How every layer of science's "self-correcting machinery" failed when Iva Veseli and I simply wanted to reproduce the findings of a high-profile study on gut microbiome and autism:

merenlab.org/2026/04/15/u...

6 days ago 162 80 12 21

One of the best decisions ever made by the biodiversity community in Singapore was to have their annual showcase/roadshow at shopping malls, which are still heavily frequented by the public in Singapore. People don't read, but impact is more likely when you take science to where the masses are

3 days ago 7 2 0 0
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Pancreatic cancer mRNA vaccine shows lasting results in an early trial Scientists caution that more research is needed, but nearly all of the patients who responded to the personalized vaccine are still alive six years later.

My father survived a year with pancreatic cancer but it was a year of terrible suffering. This is very encouraging news.

www.nbcnews.com/health/cance...

3 days ago 5771 1110 167 76
‘Invisible’ birds spotted with thermal imaging
Approach could help reveal which migrating species are most vulnerable to wind turbines and light pollution

‘Invisible’ birds spotted with thermal imaging Approach could help reveal which migrating species are most vulnerable to wind turbines and light pollution

A new technique quite literally shines a light on birds that would otherwise be invisible.

Learn more: https://scim.ag/4cwdaze

5 days ago 34 11 1 1

We (with @dornhaus.bsky.social) finally wrote up our class on how to teach modeling to biologists, which ends up being a non-trivial exercise in understanding the roles that theory plays in the scientific method. We hope others will use our class, or simply enjoy the manuscript!

6 days ago 33 11 1 1
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Can you believe that until now there were more genomes sequenced for the woolly mammoth than for living African elephants?

Today, we bring you the first genomic, continent-scale analyses of 232 high-quality genomes of both species, the savanna and forest elephant.

www.nature.com/articles/s41...

6 days ago 145 49 5 2
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A diagram showing the evolutionary relationships among modern birds. The branches are color coded by the estimated likelihood of retaining ancestral character variability, with higher likelihoods in red.

A diagram showing the evolutionary relationships among modern birds. The branches are color coded by the estimated likelihood of retaining ancestral character variability, with higher likelihoods in red.

A new paper I'm on is out today! Led by Stanley Somogyi, we suggest that ancestrally variable characters stabilized independently in different bird lineages, causing distantly related groups to retain similar traits and creating headaches for bird systematists. www.cell.com/current-biol... 🪶🧪

1 week ago 60 24 1 0
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NSF names record number of graduate fellows, rebounding from 2025 dip Distribution by field is also closer to the norm than last year’s class

NSF names record number of graduate fellows, rebounding from 2025 dip

www.science.org/content/arti...

1 week ago 13 8 0 0
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Coalescence and translation: A language model for population genetics | PNAS Probabilistic models such as the sequentially Markovian coalescent have long provided a powerful framework for population genetic inference, enabli...

Okay this is a pretty cool "language" model application, training a model on simulated demographic and mutational histories to infer coalescence times along genomes

Coalescence and translation: A language model for population genetics

1 week ago 3 1 0 0

Not the main point here, but I do not ever recall a federal agency making significant programmatic and personnel changes as a result of the PRESIDENT'S BUDGET PROPOSAL, which does not change any law or funding allocations. Congress hasn't acted yet.

What are we doing here?

2 weeks ago 2055 588 46 22
Two Promethea moth caterpillars

Two Promethea moth caterpillars

New paper! If trees are closely related, does it matter where they are from to plant-eating insects? We raised >950 Promethea moth caterpillars on 14 Prunus species to answer that question. Turns out, it matters a lot! Non-native trees = Lower performance

OA paper here: doi.org/10.1002/ecs2...

11 months ago 242 82 7 13
Screen shot of section 1.1 of the report "vision for a new publication culture"

Screen shot of section 1.1 of the report "vision for a new publication culture"

The governing body for 14 Dutch universities (UNL) has published a "Vision on Publication Culture" that is so inspiring and forward thinking. Worth a read for those trying to changes publishing and research assessment practices.

Take a read:

www.universiteitenvannederland.nl/files/public...

2 weeks ago 39 29 4 2
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In an age of creeping relativism, a universal moral law still exists.

Threatening to end an entire civilization of 90 million people in order to bend a nation’s conduct to your will is grossly morally wrong. It is evil. And we should say this loudly.

2 weeks ago 15632 4913 1536 427
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NSF LTER program “archived”.

LTER=“Long Term Ecological Research”.

This program has been incredibly successful, incredibly frugal for what they accomplish, and…of course…targeted by evil know-nothings.

My heart is breaking.

2 weeks ago 385 189 18 61
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Genomic erosion across avian lineages in the context of their evolutionary history Abstract. Loss of genetic diversity threatens species survival, yet its dynamics and impacts can vary widely across species depending on their evolutionary

Genomic erosion across avian lineages in the context of their evolutionary history
academic.oup.com/mbe/advance-...

2 weeks ago 18 8 0 0
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This planet — with all its troubles — is worth caring for.

That should be our single purpose, as a species: To be stewards of this magnificent world, ensuring it thrives long into the future.

2 weeks ago 4838 1086 187 77
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Health Insurance Claim Denied? See What Insurers Said Behind the Scenes Learn how to request your health insurance claim file, which can include details about what your insurer is saying about you and your case.

When an insurance company is deciding whether to pay for your medical treatment, it generates a file, which should contain all records associated with your case, including documents explaining why the claim was denied.

You have a right to see this file.

(Published May 2023)

2 weeks ago 1410 601 15 12

Fifty research lab shuttered. Countless decades-old experiments and scientific records lost. Thousands of forest scientists and experts essentially forced into retirement. The destruction of science on a massive scale.

2 weeks ago 354 170 17 8

We built the first complete genome for the common marmoset, fully resolving regions that were previously missing: centromeres, acrocentric short arms, and more. A new reference genome for anyone working with marmosets. This was an awesome collaborative effort & I’m grateful to all my co-authors! 🧬

3 weeks ago 36 14 2 0
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New preprint! We sequenced 175 'Alalā (Hawaiian crow) genomes to understand why >50% of eggs fail to hatch in a species recovered from just 9 individuals. What we found was a both exciting and surprising. www.biorxiv.org/content/10.6...

3 weeks ago 162 66 9 7
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Species range shifts often speed ahead of their modeled climatic niches | PNAS Anticipating how species distributions will shift with climate change is key for biodiversity conservation and management. Commonly, species’ range...

After 4yr of hard work to compare empirical species range positions' shifts from the #BioShifts DB against predictions from niche-based models trained on climate & tailored to methodological attributes of each species & study, we found species shift ahead of models' predictions! 🦋

shorturl.at/vOmCw

2 weeks ago 61 26 1 0
Science magazine cover featuring a close-up of an adult koala and joey nuzzling, with cover text about bottleneck recovery in koalas and an overlaid caption reading “Reference genomes enable discovery.”

Science magazine cover featuring a close-up of an adult koala and joey nuzzling, with cover text about bottleneck recovery in koalas and an overlaid caption reading “Reference genomes enable discovery.”

Koala clinging to a tree trunk in a forest setting, with overlaid text explaining that a reference genome is the foundation, not the finish line, and noting that the original koala reference genome was published in 2018 and later improved to support deeper population-level analysis.

Koala clinging to a tree trunk in a forest setting, with overlaid text explaining that a reference genome is the foundation, not the finish line, and noting that the original koala reference genome was published in 2018 and later improved to support deeper population-level analysis.

🐨🧬First came the reference genome. Then came the deeper story. Biodiversity genomics is helping reveal resilience and recovery across wild koala populations. 🐨
This study is a reminder that reference genomes are not the finish line, but the foundation for discovery.

@bioplatformsaus.bsky.social

2 weeks ago 30 14 1 0
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BREAKING: Trump Administration Orders Dismantling of the U.S. Forest Service The headquarters is going to Utah. Every regional office is being shuttered. The research program is being destroyed.

the trump administration is selling this country wholesale to rapacious, extractive industries that will destroy our collective resources for private profit morethanjustparks.substack.com/p/breaking-t...

2 weeks ago 7416 3367 208 2
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Hey y'all. I'm a month late to this, but I wanted to share that one of my PhD chapters was published in Systematic Biology with my advisor, Frank Burbrink. Here, we explore how ecological opportunity influences phenotypic evolution in North American natricid snakes. 🧵/8

3 weeks ago 66 27 1 0
Comparison of maxent and logistic models

Comparison of maxent and logistic models

Do you like Maxent? You can now use it within SpeciesDistributionToolkit.jl 🎉

We have also added a bunch of dataviz functions, including bivariate and value-suppressing maps. Oh, and conformal prediction for uncertainty quantification. And more coming soon.

poisotlab.github.io/SpeciesDistr...

🌏

3 weeks ago 22 12 1 0
A species tree and a cloudogram, both showing how much gene tree discordance there is in rockfishes

A species tree and a cloudogram, both showing how much gene tree discordance there is in rockfishes

New paper led by Yu Mo, with @psudmant.bsky.social

Ever wonder how extreme genealogical discordance can help you to find the genetic basis for trait variation? Wonder no more!

www.biorxiv.org/content/10.6...

3 weeks ago 25 5 0 0
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