To follow up on this, I've gotten to an age / point in my career where I often look back and am in awe at how far we've progressed. I used to do single-unit recordings of the LC 20+ years ago. Back then, we used to imagine these figures from the little we knew. Brilliant and impressive.
Delighted to share our discoveries about one of the brain's neurotransmitter systems:
www.biorxiv.org/content/10.6...
Together with colleagues at the @alleninstitute.org, we have learned a lot about a tiny cluster of neurons in the brainstem locus coeruleus (LC) that releases norepinephrine (NE). 1
Press TV also shows some good ones every so often, but they're more for a general audience (themes of solidarity, sacrifice, etc.) and not quite as hard-hitting as this.
It’s 75 here. Probably more humidity there?
How hot is it in Maryland right now? The guy seems to be sweating like crazy.
About the same temp here. I’m planting things and spreading compost in the sun and I’m not sweating the way he is.
A direct hit on our two National Clonal Germplasm Repositories would be devastating. Big, if true.
Not sure if we can rename it "The American Gulf" after "Gulf of America" is already taken.
I cannot stop thinking of all the amazing and wonderful people I have known from Israel, Iran, Lebanon and other countries caught up in this war. It is people just like them who are being killed and harmed here.
Californians are incorrigible. What stage between "parking" or "the character of the neighborhood" and "we don't need more housing, we need affordable housing!" is "TRAFFIC!!!" at in the kill-development at any cost scale?
An utterly bleak picture of the future of academic science in America
I’m sure there’s a sizable population of folks with late stage Huntington’s who ride motorcycles and present at the ER with TBI needing surgery who could be used as controls…
/s Sounds like the treatment didn’t work.
I am just now catching up on the fact that the FDA was demanding Uniqure do sham brain surgeries (from what I can tell, comprising simulated burr holes and 10-12 hours of anesthesia) in their placebo arm for their Huntington's therapeutic, and I'm absolutely floored that this was a serious demand.
"Lunar gravity predicts sleep timing" - bookmarking this lunar rhythms & sleep paper as interesting. It uses a 30-day rhythm but not the 28-day declination rhythm - a claim of "gravity" should probably use the 28-day one, but I think "phase" should follow 30?
europepmc.org/article/med/...
Shot:
www.nature.com/articles/s41...
Chaser:
Yes! We literally cannot shut up about our work.
$300 Million in jet planes lost to a fuckup.
That’s 83 five year NIH R01 grants burned in minutes due to error, aka poor execution of this unnecessary war which serves only to make the world more dangerous.
“The transition”? To what? Back to the way daddy ran things?
Cool cool cool 🫠
The ratstronaut dataset is available on DANDI!
(and analyzed with @pynapple.bsky.social 😍)
youtu.be/OkvjhWirED8?...
A simple blood test might one day serve as a molecular ‘clock’ that predicts not only whether someone will develop Alzheimer’s disease — but when
go.nature.com/4kHqfsV
When planting our garden, I sowed year-round wildflower varieties (here = Central Valley) so that bees in hive boxes in the orchards would know to visit anytime for food. Hoping that they'd also pollinate my fruit trees in the spring. Worked fine so far.
This is a very cool visualization of that.
Definitely a huge win for higher ed. I think it's important to point out that the suit that led to this outcome was brought by *UC faculty and unions* and not the UC system. The academic workers are fighting back, and we should support them.
This is a genuinely huge, sweeping victory today for the University of California—or rather, for us, its faculty, acting through our faculty associations, while the UC itself maintained a strict policy of deer-in-headlights silence.
The Trump admin has given up its appeal of a powerful injunction:
Depressed? Anxious? Lonely?
What if mental health doesn’t just result from media use, but shapes how we choose media?
In a new preprint, Valerie Klein, @gongxuanjun.bsky.social @aeden.bsky.social and I and I test this using a computational decision-making model: doi.org/10.21203/rs....
🧵Thread
Regardless of your political views or perspectives on the region, this is a moment when simple acts of compassion, such as brief messages of support or offers of collaboration with colleagues based in Iran, can make a meaningful difference. hashtag#science_diplomacy.
If you have a chance to collaborate with an Iranian scientist, do it: I've always been struck by the quality and ingenuity of the work of my colleague/collaborator in Tehran. With devastatingly few resources, he makes big things happen! I wish we have a chance to meet in person one of these days.
Join us as we post the answers to the #AMA #AskMeAnything with Editors in Chief Drs. Allan Pack (SLEEP) and Sean Drummond (SLEEPAdvances) over the next two weeks!
Question 1: What types of paper submissions would you like to see more of in 2026? 📝
🎤See the EICs' responses below!
Question 2: What advice do you have for a trainee interested in getting more experience with editorial responsibilities?
🎙️See the Editor-in-Chiefs' responses below!
