📢Fabulous new paper from @tspiresjones.bsky.social, @clairedurrant1.bsky.social & team describes new mechanisms in Progressive Supranuclear Palsy, suggesting that targeting tau in synapses is a promising approach for future treatments.
Full paper➡️www.nature.com/articles/s41593-025-01992-5 🧠
Delighted to share our paper examining synaptic tau in PSP. Many thanks to @robertmcgeachan.bsky.social @clairedurrant1.bsky.social and our many collaborators and funders. And extra special thanks to tissue donors who make this work possible.
Medium rare. Vanishingly common. Not rare but not not uncommon.
My amazing pal Gene Koh strikes again! #InDel #CancerGenomics #MutationalSignatures @naturegenet.bsky.social
Prescient urban planners installed this lovely sculpture of the Down Jones index in Cambridge 😌.
#stockmarketcrash
Today is the 17th BDIAP Approach to Cut-Up Study Day! The study day provides an opportunity for attendees to learn more about how to tackle some of the complex specimens that they may encounter in their departments.
#PathologyStudyDay #CutUpPathology #MedicalTraining #Pathologist #MedicalEducation
The 10th BDIAP Molecular Pathology Study Day has started!
#PathologyStudyDay #CutUpPathology #MedicalTraining #Pathologist #MedicalEducation #HealthcareProfessionals #StudyDay #BookNow
#pathology #histopathology #pathologyeducation #biomedicalscientist #pathologists
Excited to share our review on astrocyte aging, out today! Hopefully the only Friday surprises this week are Liddelow lab publications! 🧪 #neuroskyence @liddelowsa.bsky.social
Dr Hunter was sassy 😌😂
Great new work by Brian MacVicar's team, showing that pericytes and perivascular fibroblasts are distinct subpopulations of stromal progenitor cells in the adult brain that coordinate revascularization and scar formation after injury. #cerebrovascular #stroke #pericytes
This is how post-mortems should be documented 😉. From: Descriptive catalogue of the pathological series in the Hunterian Museum of the Royal College of Surgeons of England (1966) #PathSky
"The drowsy stillness of the afternoon was shattered by what sounded to his strained senses like G.K. Chesterton falling on a sheet of tin." P. G. Wodehouse
Office desk without any personal items or decor
Today, along with 2,000 other NIH employees, I had to clear out my office 😭
It was truly the honor of my life to work with such incredibly passionate people focused on improving human health. I’ve never experienced a more positive culture where *everyone* cared about their job and serving others.
@physoc.bsky.social has a starter pack of physiologists. Hooray!! go.bsky.app/2KU1XD6
A Perspective from @sierralab.bsky.social on #microglia as hunters or gatherers of brain synapses
www.nature.com/articles/s41...
2025 resolution: leave the pit that is Cambridge
Waking out of my sleep on a sudden, I did with my elbow hit my wife a great blow over her face and nose, which waked her with pain, at which I was sorry, and to sleep again.
Choose 20 books that have stayed with you or influenced you. One book per day for 20 days, in no particular order. No explanations, no reviews, just covers.
#Books #BookSky #BookChallenge
Day 13 (ish)
Cancer Ward, Aleksandr Solzhenitsyn
My neuroscience Christmas decorations c. 2013
Choose 20 books that have stayed with you or influenced you. One book per day for 20 days, in no particular order. No explanations, no reviews, just covers.
#Books #BookSky #BookChallenge
Day 12
War and Peace, Leo Tolstoy
Choose 20 books that have stayed with you or influenced you. One book per day for 20 days, in no particular order. No explanations, no reviews, just covers.
#Books #BookSky #BookChallenge
Day 11
Vanity Fair, William Makepeace Thackeray
Choose 20 books that have stayed with you or influenced you. One book per day for 20 days, in no particular order. No explanations, no reviews, just covers.
#Books #BookSky #BookChallenge
Day 10
Middlemarch, George Eliot (Mary Ann Evans)
Choose 20 books that have stayed with you or influenced you. One book per day for 20 days, in no particular order. No explanations, no reviews, just covers.
#Books #BookSky #BookChallenge
Day 9
A Manual for Cleaning Women, Lucia Berlin
Choose 20 books that have stayed with you or influenced you. One book per day for 20 days, in no particular order. No explanations, no reviews, just covers.
#Books #BookSky #BookChallenge
Day 8
The Prime of Miss Jean Brodie, Muriel Spark
Choose 20 books that have stayed with you or influenced you. One book per day for 20 days, in no particular order. No explanations, no reviews, just covers.
#Books #BookSky #BookChallenge
Day 7
The Grapes of Wrath, John Steinbeck
Thrilled to see this paper out!! 🧪
Spatial transcriptomics of brain aging and 'spatial aging clocks' identify cells that have pro-aging or pro-rejuvenating effects on their neighbors!
Huge CONGRATS to Eric Sun and all authors! Fantastic collaboration with @jameszou.bsky.social!
rdcu.be/d33uQ 🧵
I'm excited to share another project we've been working on: The Transmitter's first book, which includes some of our favorite essays from our first ~9 months. Download a copy here: www.thetransmitter.org/transmitter-...
Choose 20 books that have stayed with you or influenced you. One book per day for 20 days, in no particular order. No explanations, no reviews, just covers.
#Books #BookSky #BookChallenge
Day 6
Bleak House, Charles Dickens
Suitably miniature mince pies for the microscopist in your life.
?asteroid bodies
#pathsky
We're so excited to join the party over here! Follow this account to learn more about the latest papers published in Nature Neuroscience!