📢 Job opportunity: Research Associate in lung epigenetics at Cardiff University with Dr Renata Jurkowska
📅 Deadline: 4 March

🔗krb-sjobs.brassring.com/TGnewUI/Search/Home/Home...

We will miss having you there!

This will be a great meeting! Don't forget to register!

Congratulations! I look forward to reading it.

Congrats Vincent and team! I look forward to reading it

Our latest collaboration with the talented Susi @sbantele.bsky.social and Jiri Lukas is out now @science.org 🤩. We reveal the hidden price for DNA repair, with potential implications for genome function, gene therapy and ageing👇

Spread the word! There is a professor position opening at our University @upcite.bsky.social. There are several possible (great) labs to join, but if you are interested in DNA methylation and epigenetics in mammals, don't hesitate to contact me directly!

An interview with Azim Surani Professor Azim Surani is the Director of Epigenomics and Germline Imprinting at the Gurdon Institute in Cambridge, UK. He is this year's recipient of both the prestigious Kyoto Prize and the Paul Ehrl...

I didn't think I could admire Azim Surani more than I already did
journals.biologists.com/dev/article/...

The mini placentas and ovaries revealing the basics of women’s health Lab-made organoids that mimic reproductive tissues could point to treatments for common conditions such as pre-eclampsia and endometriosis.

An insight into advances in the field of placental biology and their importance: www.nature.com/articles/d41...

Epigenetic relay: Polycomb-directed DNA methylation in mammalian development In mammals, repression of germline-specific gene expression is essential for preserving somatic cell identity and preventing disease. Germline gene silencing is often dependent on the presence of prom...

Very excited to share an excellent review from @teresa-urli.bsky.social, published one week before her PhD defense! We did a deep dive into the fascinating biology of the variant Polycomb complex, PRC1.6 (1/5) journals.plos.org/plosgenetics...

Congrats! Looking forward to read it!

Why would anyone want to be a scientist? It is difficult to fathom why anyone intelligent enough to be a scientist would actually choose to be one. Doing good science requires the utmost exertion of body, mind and spirit, yet is consistently...

"why [would] anyone intelligent enough to be a scientist choose to be one [given] the unfavorable risk-to-reward ratio "?

One of the most intelligent people you could meet offers some answers: having ideas, watching them develop, and sharing them journals.biologists.com/jcs/article/...

Congrats to @clairesimon.bsky.social and @niakanlab.bsky.social! We were happy to contribute to this great project investigating FGF/ERK signalling in human embryogenesis. @georgiaplea.bsky.social

Congrats Rebecca!

Looking forward to it!! 😀

Congrats! Really looking forward to reading this!

Divergent DNA methylation dynamics in marsupial and eutherian embryos - Nature A study reports on the DNA methylation dynamics during embryogenesis in marsupials, showing that these differ from those occurring during embryogenesis in eutherian mammals.

We're excited to publish our latest study led by Bryony Leeke @bryonyleeke.bsky.social and Wazeer Varsally, now out in @nature.com 🍾This study focusses on the epigenome of marsupial embryos 🦘 mapping DNA methylation in embryo development to specific embryo events www.nature.com/articles/s41... 🧵

@c-jake-harris.bsky.social looking forward to reading this!

YEN 2025 Conference: Registration is open! - the Node Register now for the Young Embryologist Network meeting - Monday 19 May 2025 at the Francis Crick Institute. Are you an early career researcher in

Registration open for this year's Young Embryologist Network meeting

19 May, The Francis Crick Institute, London

thenode.biologists.com/yen-2025-con...

We are hiring! 3-year BBSRC-funded postdoc position available. TEs, epigenetics, pregnancy: if you love one or more of these keywords, apply through the link below.
Please spread the word.

Compared to early human trophoblast, hTSCs lack DNMT3L expression, which is necessary for PMDs in mouse trophoblast. When we ectopically express DNMT3L in hTSCs, we find placental PMDs are restored, supporting a conserved role for DNMT3L in de novo methylation in trophoblast.

The placental DNA methylation landscape is unique compared to all other cells of the body, with widespread partially methylated domains (PMDs). hTSCs exhibit widespread loss of PMDs and this pattern is persistent, regardless of cell origin, oxygen levels or culture conditions.

Ectopic expression of DNMT3L in human trophoblast stem cells restores features of the placental methylome The placental DNA methylation landscape is unique, with widespread partially methylated domains (PMDs). The placental “methylome” is conserved across …

Excited to share our most recent work in Cell Stem Cell, led by @georgiaplea.bsky.social, characterising determinants of DNA methylation patterning in human trophoblast stem cells! A great collaboration with @vpglab.bsky.social.
tinyurl.com/93mchcd2

@loke-ctr.bsky.social @cam-repro.bsky.social