Graphic in dark blue and white. The text reads: New research. Reforming the delivery of smoking cessation: a distributional cost-effectiveness analysis of providing smoking cessation as part of targeted lung cancer screening. Journal of Medical Economics. There is a photo of stop sign with a cigarette through it. The YHEC 40th anniversary logo is in the top right hand corner.

Can smoking cessation services be designed to reduce health inequalities? A study co-authored by Harriet Fewster, Robert Malcolm and Hayden Holmes uses distributional cost-effectiveness analysis to assess integrating cessation into a lung cancer screening programme. Read more: tinyurl.com/2nkjzy5n

"Graphic in maroon and white. There is a photo of YHEC's Nick Hex. The text reads: Parliamentary event. The Future of Sepsis Care. Nick Hex, Director of NHS Consulting. Monday 20 April. The YHEC logo is in the top right hand corner."

We’re pleased to share that YHEC’s Nick Hex is speaking today at a parliamentary event on The Future of Sepsis Care. The reception brings together parliamentarians and stakeholders to explore how improvements in sepsis care can be achieved. Contact us to find out more: www.yhec.co.uk/contact-us/

"Graphic in blue and white. There is a picture of a woman with a mobile phone. The text reads: New research. Supporting early diagnosis in endometriosis: the cost-effectiveness of digital symptom checkers. Digital symptom checkers are increasingly used to support early symptom recognition and care-seeking. YHEC’s Laura Kelly co-authored an economic evaluation on a digital symptom checker for endometriosis. The YHEC 40th anniversary logo is in the top right hand corner."

What is the economic cost of delayed diagnosis? YHEC's Laura Kelly has co-authored a study exploring the potential value of digital symptom checkers for endometriosis. It models whether earlier symptom recognition could improve outcomes and reduce costs. Read more: www.nature.com/articles/s41...

Graphic in pink and white. The text reads: Recommendations for overcoming methodological challenges to health economic modelling that arise when comparing in vitro diagnostics with imaging tests. Health Services and Outcomes Research Methodology . There is a photo of a woman in a white coat and mask in a laboratory holding a test tube. The YHEC 40th anniversary logo is in the top right hand corner.

Comparing in vitro diagnostics with imaging tests in HTA is methodologically complex and often oversimplified. A new paper co-authored by YHEC's experts identifies the key challenges and provides recommendations for future work in the field.

Read more: link.springer.com/article/10.1...

Graphic in pink and white. There is a photo on the right of a woman's face and upper body, she is holding a model of a stomach. The text reads: New research. Cost-effectiveness of RefluxStop for gastroesophageal reflux disease: analysis from an Italian healthcare perspective. BMC Gastroenterology. The YHEC 40th anniversary logo is in the top right hand corner.

A new paper, co-authored by YHEC’s Sam Harper and Stuart Mealing, provides evidence for a changing gastroesophageal reflux disease treatment landscape.

Read the full paper: link.springer.com/article/10.1...

#HealthEconomics #GERD #MedTech

A green graphic with the YHEC 40th anniversary logo in a navy box in the upper right corner. In the bottom right corner, there is a picture of Melissa and text that reads: "Melissa Pegg, Senior Research Consultant" On the left of the graphic, "conference speaker" is in a navy box and below, the text reads: "A Call For Action: Safe Environment, Safe Public and Health and Sustainable Pharmaceuticals: Environmental Impact and Formularies. Developing a Simplified Environmental Formulary Framework in Saudi Arabia. 4th Formulary Management Conference, Tuesday 14 April, 11:00am AST"

Can we balance patient access to medicines with the urgent need for environmental protection? 🌿

Next week, YHEC’s Melissa Pegg will be speaking at the 4th Formulary Management Conference, contributing to the conversation on environmental sustainability within healthcare.

#FormularyManagement #HTA

Graphic in green and blue. There is a headshot of Stuart Mealing. The quoted text reads: "I joined NICE’s Highly Specialised Technologies Evaluation Committee because I was keen to use my skills to have a direct and, hopefully positive, impact on the NHS. During my time, the experience has been both challenging and energising. As a committee, we regularly find ourselves wrestling with difficult scientific, ethical, and practical considerations, working collectively to reach consensus decisions that can genuinely move the needle forward for patients with ultra-rare conditions." Stuart Mealing, Director of Pharmaceutical Consulting. The YHEC 40th anniversary logo also features

What does HTA look like when the condition is ultra-rare and the evidence is anything but straightforward? In our latest blog, YHEC's Stuart Mealing shares his experience as a member of NICE’s Highly Specialised Technologies Evaluation Committee (HSTEC).

Read more: www.yhec.co.uk/resource/a-s...

Graphic in pink and white. The text reads 40 years of evidence, insight and impact. There are fireworks and the YHEC 40th anniversary logo is in the top left hand corner.

Happy birthday YHEC! 01 April 2026 marks 40 years of YHEC: four decades of research, collaboration and contribution to healthcare decision-making.

We’re proud of our past and excited for what’s still to come.
Read more about YHEC on our blog: www.yhec.co.uk/resources-an...

#40YearsOfYHEC

Picture of doctors in discussion. Text says NICE and MHRA aligned pathway launches 01 April. The YHEC 40th anniversary logo is in the bottom right hand corner.

The NICE–MHRA aligned pathway was launched today, marking an important development for medicines access in England. If you would like to discuss what this could mean for your product, portfolio, or evidence strategy, contact us: www.yhec.co.uk/contact-us/.

An image of Melissa Pegg standing at a podium at the front of the room giving a presentation at DIA Europe.

Last week at #DIAEurope2026, YHEC’s Melissa Pegg discussed environmental sustainability in HTA and the medicines lifecycle.
It was fantastic to collaborate with so many peers committed to driving change. Now, it’s time to put those methods into practice.

Contact us at: www.yhec.co.uk/contact-us/

Graphic in white and pink. There is a headshot of Andria Joseph. The quoted text reads: "It is exciting to see the publication of the new UK EQ-5D-5L value set in Value in Health. For those working across HEOR, HTA and market access, this is a significant development for the UK evidence landscape. For HEOR, this matters because the choice of value set can directly influence utility estimates, QALY calculations and, ultimately, the results of economic evaluations." Andria Joseph, Project Director. The YHEC 40th anniversary logo also features

It is great to see the publication of the new UK EQ-5D-5L value set in Value in Health. For those working across HEOR, HTA and market access, this is an important development for the UK evidence landscape.

Want to discuss what this means? Get in touch: www.yhec.co.uk/contact-us/

#HEOR #HTA #EQ5D

Graphic in blue and white. There is a photo on the right of a man in a bed with his right leg in a cast. The text reads: New research. Early cost-effectiveness analysis of continuous compartment pressure monitoring modelled in patients with a fracture of the tibial diaphysis. Injury. The YHEC 40th anniversary logo is in the top right hand corner.

New evidence on continuous pressure monitoring (CPM) in a new paper co-authored by YHEC’s Sam Harper and Ciara Buckley. The study models the cost-effectiveness of CPM for patients at risk of acute compartment syndrome following tibial diaphyseal fracture.
Read more: doi.org/10.1016/j.in...

An image of Riyadh, Saudi Arabia. In the upper right corner there is a white box including the YHEC 40th anniversary logo and blue text below reading: "We are speaking at the 4th Formulary Management conference 2026"

As global healthcare leaders look for ways to reach Net Zero, the environmental impact of pharmaceuticals is becoming a critical part of the conversation. YHEC’s Melissa Pegg will be speaking at the 4th Formulary Management Conference in Riyadh!

📅 13 to 14 April 2026
📍 Riyadh, Saudi Arabia

Screenshot of the YHEC newsletter front page, with a picture of the YHEC offices and the YHEC logo. The text reads "Welcome to YHEC's March 2026 Newsletter"

40 Years of Impact: The YHEC March Update

From the halls of the WEPA Congress in Amsterdam to the latest peer-reviewed insights in #HealthEconomics, March has been a great month for the YHEC team.

Read our latest newsletter to find out more! createsend.com/t/y-81DD459B...

Graphic in pink and white. The text reads: AI evaluation community of interest group. Guest speaker: Professor Ibrahim Habli, University of York. Hosted by: Hayden Holmes, YHEC Director of Digital Health Consulting. Angel Varghese, YHEC Project Director. There are headshots of Professor Habli, Hayden Holmes and Angel Varghese. The University of York and YHEC 40th Anniversary logos are both featured.

Last week, YHEC hosted an AI Evaluation Community of Interest Group meeting to discuss evaluating AI in clinical settings. Facilitated by Hayden Holmes and Angel Varghese, the session featured a talk by Professor Ibrahim Habli from the University of York. Contact us to find out more: www.yhec.co.uk

Graphic in orange and maroon. The text reads: We are hiring. Research consultant: outcomes research. Visit YHEC.co.uk to apply. The YHEC 40th anniversary logo is also featured.

Interested in outcomes research? We are looking for a Research Consultant to join our team. If you have experience or a strong interest in real-world evidence and the measurement of clinical, patient-reported and service outcomes we want to hear from you: www.yhec.co.uk/careers/vaca...

Graphic in green and blue. The text reads: The UK Diabetic Foot Congress. 19 June 2026. Hilton Leeds City. www.ukdfc.co.uk. Guest speaker Nick Hex, Director of NHS Consulting. There is a headshot of Nick Hex. The YHEC 40th anniversary logo is featured alongside the UKDFC logo.

We are excited to share that YHEC's Nick Hex will be speaking at the inaugural UK Diabetic Foot Congress in June. Nick’s talk will focus on the economic burden of diabetic foot ulcers in England, highlighting NHS costs, outcomes and opportunities for savings. Registration is open: www.ukdfc.co.uk

The graphic has a green background with the YHEC 40th anniversary logo in a navy box in the top right corner. In the bottom right of the graphic, there is a head and shoulder picture of Melissa Pegg with the text: ""Melissa Pegg, Senior Research Consultant"". On the left of the graphic, the text reads: ""Conference panel: Sustainability, Access, and Value: Building Environmental Considerations into the Evaluation of Health Interventions. DIA Europe 2026, Tuesday 24 March 01:00pm CET.

How can we build environmental considerations into the evaluation of health interventions? YHEC's Melissa Pegg will be sharing her insights at the Drug Information Association (DIA) Europe 2026 conference in Rotterdam on 24 March.

Read Melissa's blog:
🔗 www.yhec.co.uk/resource/how...

#DIAEurope

Graphic in blue and white. There is a photo on the right of a woman's face and elbow with psoriasis on the elbow. The text reads: New research. Healthcare resource use of patients with mild-moderate psoriasis on systemic treatments: a UK single-center longitudinal retrospective cohort study. Journal of Dermatological Treatment. The YHEC 40th anniversary logo is in the top right hand corner.

Are people with psoriasis being underserved by current treatment pathways? New research co-authored by YHEC’s Joe Moss, Erin Barker and Neil Hansell highlights a substantial clinical and economic burden, despite ongoing systemic treatment. Read more: www.tandfonline.com/doi/full/10....

#Psoriasis

A blue graphic with the YHEC 40th anniversary logo in the top left corner. On the left of the graphic, there is the ECR 2026 logo. On the right, the text reads: "Conference panel. Value-based radiology and its broader impact. European Congress of Radiology 2026."

YHEC's Andria Joseph joined a panel at ECR 2026 to discuss value-based radiology. Her message was clear: radiology and imaging AI must show how they improve clinical decisions, affordability and equity, rather than just increasing throughput.

To find out more, contact us: www.yhec.co.uk/contact-us/

Graphic in green and blue. The text reads: "Online training. Environmental Sustainability Webinar Series. What are Carbon Emissions and Scope 1–3? Friday 24x April, 1pm. There is a headshot of Melissa Pegg and the text says: "Melissa Pegg: Senior Research Consultant." The YHEC 40th anniversary logo is in the top right hand corner.

Join YHEC Senior Research Consultant Melissa Pegg for the latest webinar in our free series on the foundations of sustainable healthcare.

April’s webinar: What are Carbon Emissions and Scope 1–3?

📅 Friday 24 April
🕐 1pm

Register and sign up for the webinar series:
www.yhec.co.uk/product/free...

Orange graphic with the following quote: "The fact is that health economists have always been in high demand, so career prospects are very good. And health economics is a fascinating subject with many sub-branches which provides opportunities to become an expert in many different specialties." John Posnett

For 40 years, YHEC has been shaped not only by its projects, but by the people who have been part of its journey. In these three blogs, Adam Gordois, John Posnett & Andy Street share memories from the early years of YHEC and reflect on the career path that followed.

Read more: tinyurl.com/phj8asre

A pink graphic, with a photo of YHEC's Stuart Mealing on the left side. Above, there is a YHEC 40th anniversary logo in the upper left corner. On the right there is a quote from Stuart that reads: "The conference felt a lot bigger than last year but still retained the relaxed, collaborative feel, with plenty of time to catch up with people and have meaningful conversations. All of the talks I attended were insightful and of a really high standard. Unsurprisingly, there was a lot of discussion around AI but there was more about MFN than I had expected. I also attended some interesting perspectives on the inclusion of the patient voice into the HTA process. It’s clear that these are becoming essential considerations for the industry moving forward." Below this, text reads: "Stuart Mealing, Director of Pharmaceutical Consulting"

Our Director of Pharmaceutical Consulting, Stuart Mealing, reflected on attendance at the World Evidence, Pricing and Access Congress last week. AI and most-favoured nation (MFN) were key themes.

Looking for strategic guidance on your next HTA submission? Contact us: www.yhec.co.uk/contact-us/

Green and blue graphic advertising a course. The text reads: Online training course. Systematic, scoping, rapid, overview and living reviews - what they are and when and how to use them. Self-guided, online training, produced in collaboration with ISPOR. YHEC speaker: Mary Edwards, Senior Rsearch Consultant. There is a photo of Mary Edwards and the YHEC 40th anniversary logo and the ISPOR Education Series logo are both featured.

Right question, wrong method? Systematic reviews are seen as gold standard but they may not fit every product life cycle stage. Gain insights from YHEC's Mary Edwards in this self-guided course produced in collaboration with @ispor.bsky.social

Enrol here: tinyurl.com/makuvn2t

#EvidenceSynthesis

Graphic in orange, with a photo of YHEC's Katie Reddish. The text reads: Congratulations! Katie Reddish has recently been promoted to Research Consultant. The YHEC 40th anniversary logo is in the top left hand corner.

YHEC would like to congratulate Katie Reddish on being promoted to Research Consultant. Well done, Katie!

Graphic in white and blue, with a photo of YHEC's Emma Bishop. The text reads: Congratulations! Emma Bishop has recently been promoted to Research Consultant. The YHEC 40th anniversary logo is in the top left hand corner.

YHEC would like to congratulate Emma Bishop on being promoted to Research Consultant. Well done, Emma!

Red and white graphic showing photos of YHEC staff at various charity events. The text says: 40 years of community impact. The YHEC 40th anniversary logo is in the top left hand corner.

As YHEC celebrates its 40th anniversary, we’re proud to reflect on a milestone beyond our research: raising £61,000+ for 13 charities since 2012 through staff-led fundraising and volunteering.

👉 Read the blog and follow our journey: www.yhec.co.uk/resource/bey...

#40YearsOfYHEC #CommunityImpact

Graphic in green and blue. The text reads: We are hiring: project director. Key information: Reviews and evidence synthesis, project management, team and business development, remote/hybrid options, visit our website to apply. The YHEC logo is in the bottom left hand corner.

📢 We’re hiring: Project Director - Reviews & Evidence Synthesis

We are seeking a senior leader in evidence synthesis to direct & deliver complex literature-based research & consultancy projects.

🕒 Full time, permanent
🗓 Closing date: 08 March 2026

🔗 Find out more: www.yhec.co.uk/careers/vaca...

An image of five YHEC members of staff standing at YHEC's conferences booth at WEPA in Amsterdam.

Day 1 at WEPA Congress is officially underway! 🚀

If you’re at the event, come and chat to us at Booth 600. Stuart, Rachael, Sam, Tom and Robert are all on-site and would love to catch up on the latest industry trends or discuss how we can support your projects.

#WorldEPACongress #MarketAccess

Graphic in pink and white. There is a photo on the left of hands using a mobile phone. The text reads: New research. Economic evaluation of a digital symptom checker for endometriosis using a Markov decision process model. npj digital medicine. The YHEC 40th Anniversary logo is in the top right hand corner.

Can digital symptom checkers reduce diagnostic delay and deliver economic value in endometriosis?

A new study, co-authored by YHEC's Laura Kelly, explores whether digital tools can deliver long-term value.

📄 Read more: www.nature.com/articles/s41...

#DigitalHealth #Endometriosis