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Posts by Lee Cronin

AI cannot in principle make novel discoveries.

1 month ago 6 1 1 0
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Quantifying the Emergence of Selection Prior to Biological Evolution Selection is central to biological evolution, yet there has been no general experimental framework for quantifying selection in chemical systems before life. Here we demonstrate that selection in a pr...

Can assembly theory & assembly equation be used to measure selection in real experiments? arxiv.org/abs/2512.18752

3 months ago 1 0 0 0
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Assembly Addition Chains In this paper we extend the notion of Addition Chains over Z+ to a general set S. We explain how the algebraic structure of Assembly Multi-Magma over the pairs (S,BB proper subset of S) allows to defi...

Assembly addition chains: arxiv.org/abs/2512.18030

3 months ago 1 0 1 0

Policing words is the same as policing thoughts. An open society should have no limits on words. Words are the meta space where ideas need to be formed and compete. If you prevent ideas you don’t like then you harm the future of the human race & usher in tyranny.

3 months ago 2 0 0 0
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With AI I can be both chemist & director.

6 months ago 9 0 0 0
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Here is Quantum Chemputation conceptually. Go from the physical properties you want to a possible molecular graph, but then apply the rules of synthetic chemistry to ensure it is Chemputatable and therefore makable.

6 months ago 9 0 0 0

Causation requires matter. But causal matter requires evolution.

6 months ago 4 0 0 0
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Chemputer and Chemputation -- A Universal Chemical Compound Synthesis Machine Chemputation reframes synthesis as the programmable execution of reaction code on a universally re-configurable hardware graph. Here we prove that a chemputer equipped with a finite, but extensible, s...

Digital chemistry won’t just happen by bolting a chatbot to a liquid handling robot. It needs a fundamental new approach to allow the programming of matter, or chemputation. The theory & practical implementation is outlined here: arxiv.org/abs/2408.09171

7 months ago 12 1 0 0
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“Chemputation” and the Rise of Digital Chemistry Discover how digital chemistry is shaping the future of drug and materials discovery through automation and scalable innovation.

www.technologynetworks.com/informatics/... #chemputation #digitalchemistry

7 months ago 6 0 0 1
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Chemputation will lead to an exponential growth of the number of molecules synthetically accessible. It transcends the limits of manual labor by using a Turing-like ontology for error correction to ensure we can go deeper into chemical space. arxiv.org/abs/2408.09171

8 months ago 8 0 0 0

We are doing so much using chemputation your ‘demands’ are mute. It simply makes no sense to imagine that all chemistry won’t be done using code.

9 months ago 0 0 1 0

AI is showing us that creativity sits in an entirely different category to data retrieval.

9 months ago 7 0 0 0
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Chemputation is universal.

9 months ago 3 0 0 0
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So we opened the worlds first Chemifarm today! www.chemify.io

10 months ago 12 0 0 1
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Now in 2025, Chemify is opening the worlds first Chemifarm, which is the first commercial facility for chemputation able to do chemical design, discovery, & manufacture on demand. www.chemifyx.com

10 months ago 5 0 0 0
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Making digital chemistry truly universal for chemputation (digital control of chemsitry) required a new approach to hardware, wetware, & software with the development of XDL. www.science.org/doi/10.1126/... Now the theory showing universality is done. arxiv.org/abs/2408.09171

10 months ago 7 0 0 0
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In 2012 I had a dream of universal digital chemistry for chemputation inspired by 3D printing technology. By 2016 we made a key advance. We went from a vision to a universal code for organic synthesis - in this case making Ibuprofen in a hacked 3D printer. www.beilstein-journals.org/bjoc/article...

10 months ago 5 1 2 0
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Chemputer and Chemputation - A Universal Chemical Compound Synthesis Machine Chemputation, the execution of code controlled reaction pathways on universally reconfigurable hardware, offers a route to treating chemical synthesis as a formally computable i.e. chemputable process...

This helps redefine what a molecule is & that blows my mind. arxiv.org/abs/2408.09171

10 months ago 8 1 1 0
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Want to know why Chemputation redefines the very concept of what a molecule is? Updated preprint arxiv.org/abs/2408.09171

11 months ago 7 0 0 0

Well we know what molecules are according to the text books, but do we know what Molecules are according the theory of Chemputation…this is coming soon (Molecules from molecules is a play on Humans from humans by @aptshadow.bsky.social).

11 months ago 4 0 1 0

Just finished redefining the idea of a molecule using assembly theory. Will preprint soon.

1 year ago 7 0 0 0
Join Chemsymposia 2026: Research & Innovation | ChemSymposia 2026 Join us at Chemsymposia 2026 to discover groundbreaking research in physics applications. Connect with experts, engage in insightful discussions, and explore our venue, registration details, and speak...

SCAM ALERT. This is a fake conference that ripped off my and other people’s names to trick people into registering. There is no such conference that I or the others shown were invited or agreed to. We are working to try to get this fraud taken down from the web.

chemsymposia.com

1 year ago 193 108 8 6

The ghost of computation makes us believe that computation is fundamental. There is no physical basis for this. Computation is a human construct

1 year ago 10 0 0 1
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Chemputers can be programmed using our chemical programming language (XDL) to make molecular machines. Great work by the team dlvr.it/TJsSjt Video done in collaboration with SciCommStudios.

1 year ago 27 6 1 0
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To solve intelligence you need to solve life, to solve life you need to solve the origin of life. Assembly theory aims to make progress across the board but progress is not guaranteed.

1 year ago 12 0 0 0

Academia is under attack by the tech bros, which is hilarious because all their ‘tech’ was invented in academia.

1 year ago 15 0 0 0

Critical thinking, freedom of speech, & freedom to disagree are hard won & should be hard won every single day. Don’t take them for granted with nonsensical isms.

1 year ago 10 0 0 0
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Saturday night radioactivity.

1 year ago 9 0 0 0
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Chemputers are Turing complete & this is going to accelerate chemistry dramatically. Chem/acc

1 year ago 12 1 1 0
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Ridge surfing in Sedona.

1 year ago 9 0 2 0