We develop a new TMS targeting algorithm and test it in an open label trial in a treatment-resistant depression population with high comorbidities. Preprints by @rubykong92.bsky.social Phern-Chern Tor
1. doi.org/10.1101/2025...
2. doi.org/10.64898/202...
Our new approach ...
Do you censor high motion frames in fMRI? In two preprints by @twktan.bsky.social @mandymejia.bsky.social, we find that we may be censoring too much!
doi.org/10.64898/202...
arxiv.org/html/2603.07...
Strict censoring leads to worse personalized TMS targets than no censoring, even with high motion!
🚨 New preprint: Objective Quality Assessment for Precision fMRI
Precision functional mapping (PFM) enables individual-level brain network studies — but demands more, and better, data.
We introduce an objective framework to determine when a dataset truly supports interpretable, replicable PFM.
Preprint on PANDORA by Aslan Abivardi:
A massive archive of UK Biobank brain imaging from 82K subjects. For each of 98 sub-modalities (e.g., FA from dMRI), the images are collated into a convenient subjectsXvoxels HDF5 file.
pages.fmrib.ox.ac.uk/pandora/web/
www.medrxiv.org/content/10.6...
Check out our new work on the relationship between glioma and system-level functional networks! We identify that nearly all gliomas localize within a common brain functional network, Action-Mode Network (AMN) .
biorxiv.org/content/10.64898/2026.01.05.697608v1
This is your brain on Ritalin. Got your attention? Stimulant medications like Ritalin (methylphenidate) do, but not in the way you might think. They don't act directly on the brain’s attention systems! Find out what's really happening in @cellpress.bsky.social. doi.org/10.1016/j.ce...
Our paper on the ☀️ "summer slide" 🛝 is out now @pnas.org!
www.pnas.org/doi/10.1073/...
Summer slide is a replicable phenomenon across diverse datasets that's more than "forgetting" school material in vacation months, but effects of socioeconomic inequality are ➡️ 7x bigger! ⬅️
#PsychSciSky #DevPsy
🧵👇
Top: Experimental set up. Single pulses of TMS were applied to the hand area of the right primary motor cortex with an inter-pulse interval randomized between 6 and 10 s. Simultaneously, the neuronavigated coil position (yellow), electrocardiogram (red), respiratory signal (blue), electrogastrogram (green), and electromyography from the left hand (gray) were recorded. The figure shows traces of a 20-s time segment from one participant of the cardiac (raw), respiratory (filtered), gastric (filtered), and EMG (raw) signals. The experimental measure was the Motor Evoked Potential amplitude measured on a hand muscle (first dorsal interosseous), analyzed against the phase of the cardiac, respiratory, and gastric rhythms. Note that the three rhythms have very different periods (~1 s for the heart, ~ 5 s for respiration, and ~20 s for the gastric rhythm). Bottom: Artwork illustrating how rhythms of the internal organs interact with the moment-to-moment fluctuations observed in corticospinal motor excitability. Image depicts an outline of a brain with representations of the three rhythmic organs influencing the motor system: the heart, lungs, and stomach. Image credit: Tahnée Engelen.
How do internal bodily rhythms influence #brain activity & motor function? @tahnee-engelen.bsky.social &co show that #cardiac, #respiratory & #gastric rhythms independently modulate motor excitability, revealing distinct #interoceptive profiles across individuals @plosbiology.org 🧪 plos.io/4nMtpLT
Nature research paper: Adenosine signalling drives antidepressant actions of ketamine and ECT
go.nature.com/3Ln1gh6
Congrats @chen-zhang.bsky.social !
Preprint is now published! doi.org/10.1002/hbm....
Thanks to co-authors @chen-zhang.bsky.social @anlijuncn.bsky.social @csabaorban.bsky.social
Preprint is now published: doi.org/10.1002/hbm....
Special thanks to co-authors @twktan.bsky.social @kimnganngt.bsky.social @csabaorban.bsky.social
Launched in 2023, Imaging Neuroscience is now firmly established, with full indexing (PubMed, etc.) and 700 papers to date.
We're very happy to announce that we are able to reduce the APC to $1400.
Huge thanks to all authors, reviewers, editorial team+board, and MIT Press.
This looks pretty cool: ultrasound can now see through the skull! 🧠🔊
The skull has long been a barrier to ultrasound. This reprint shows how to make it quickly transparent → enabling full-depth, high-res fUSI in mice (& humans! 🤯🤯)
Huge congrats to the authors!!!
www.biorxiv.org/content/10.1...
What started as a journal club on layer decoding turned into a project thanks to @karolisdegutis.bsky.social. Our preprint challenges a widespread assumption in the field: MVPA is not immune to vascular confounds in laminar GE-BOLD decoding, as shown using a mechanistic laminar response model.
This image is figure 1 showing the longitudinal investigation of participants with planned arm amputations.
Longitudinal neuroimaging of participants with planned arm amputations shows that the cortical body map remains stable after amputation. The findings, published in Nature Neuroscience, challenge long-standing theories of brain remapping after limb loss. go.nature.com/4oLSyYO 🧪 #Neuroscience
🚨 New preprint out! 🚨
“Translating the Transcriptome: A Connectomics Approach for Gene-Network Mapping and Clinical Application”
🔗 doi.org/10.1101/2025... 
🧵 A short thread:
Now out in @natneuro.nature.com
What happens to the brain’s body map when a body-part is removed?
Scanning patients before and up to 5 yrs after arm amputation, we discovered the brain’s body map is strikingly preserved despite amputation
www.nature.com/articles/s41593-025-02037-7
🧵1/18
Great write up of our @nature.com study by @claudia-lopez.bsky.social
I still get chills
Meet Mike
*30+ years severe depression
*first hospitalized @ 13y
*20 meds
*3 rounds of ECT
*2 near-fatal suicide attempts
Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE
see videos, read paper, follow thread
doi.org/10.31234/osf...
🚨 New Preprint 🚨
Targeting intracranial electrical stimulation (ES) to network regions defined within individuals causes network-level effects
By Cyr et al.
***
Q: Can we use individualized network maps from precision fMRI to modulate a targeted network via intracranial ES?
A: Yes!
🧵:
Did you know that seeing virtual avatars with coughs or rashes can trigger your brain's immune response? Read more in this fascinating Nature Neuroscience paper @natureportfolio.nature.com 🧪 www.nature.com/articles/s41...
I’m elated to share our latest publication - out now in @natmentalhealth.nature.com! www.nature.com/articles/s44... - tour de force by @leahbanellis.bsky.social @brainandstomach.bsky.social and the rest of the VMP team!
For me, this work is a classic @ohbmofficial.bsky.social story: In 2023 I wasn't working with @bttyeo.bsky.social but I overheard him at his poster pointing to some accuracy curves saying "I don't why they have this particular shape". That kicked off the collab that led to these results.
🚨Thrilled to share our latest work just published in @nature.com where we looked into the optimal fMRI scan time for brain-wide association studies (BWAS) 🧠⏱️! Full thread below👇:
Super thankful to @bttyeo.bsky.social @csabaorban.bsky.social and @shaoshiz.bsky.social for pouring in all the effort to make this work possible!
1/11 Excited to share our @Naturestudy led by @leonooi.bsky.social @csabaorban.bsky.social @shaoshiz.bsky.social
AI performance is known to scale with logarithm of sample size (Kaplan 2020), but in many domains, sample size can be # participants or # measurements...
doi.org/10.1038/s415...
Alert!!!!
“An Action Networks Model for Pain”
We propose a new model for chronic pain — and highlight two functionally connected cortical networks that could revolutionize how we treat it.
👉 thread below 🧵
osf.io/preprints/ps...
