👉 3rd aECM club Apr 14th 10 am NYC-4 pm Paris
#aECM invertebrate cuticle and molt cycle @gotworms.bsky.social
@labgrosshans.bsky.social
program sundaramlab.com/blog/aecm-cl...
👉 join our Slack forms.gle/Y6UjbnXPH1pD...
Sad to see that Don passed, he was a legend and a big part of why our community is so special. 🤯 20% of the collection?!!
You have a great weekend too!
Nice! I love that show! Pickle brine margaritas and takeout from our favorite taco truck
Great to see this out. Practical guidance on how to use protein depletion systems in C. elegans
Congratulations to the legendary scientist Judith Kimble!!!
We stand on the shoulders of giants.
#womeninSTEM #celegans
Representative immunostaining of anti-glutamylated tubulin (rMAb-GT335) in C. elegans hermaphrodites. Glutamylated tubulin is detected in labial and cephalic cilia (bracket) and the middle segments (MS) of amphid channel cilia. Scale bar=2μm.
Recombinant monoclonal antibodies to detect tubulin post-translational modifications work beautifully in #celegans neurons and cilia.
@kjverhey1.bsky.social shared ONE ML of each rMAb!
www.micropublication.org/journals/bio...
Blasius...Verhey 2025 Cytoskeleton: 10.1002/cm.70011. PMID: 40650552
I am reviewing a simply amazing paper from a relatively young US-based lab, which is in danger of shutting its doors later this year. My emotions are all over the place.
The fact that this does not uniquely identify the lab I’m referring to just deepens the tragedy of this moment in US science.
Don’t forget to register for the C. elegans topic meeting June 10-14 in Madison, WI. Early bird registration deadline this Friday 2/27! uwmadison.eventsair.com/mapsdev26/
Come join us! This meeting is going to be awesome!
Disco worms!
Can’t imagine two better people to be trusted with this legacy!
Thanks Javier!!!
Thank you! We’re really excited about it!
Us too. This one hits surprisingly hard
The CGC has added some cool functionality to improve the searchability of the site to help find appropriate strains for your research. We are working to create a consistent nomenclature. More collections to come in the future. Folks can ask questions on Worm Slack, the Alliance forum, or here! (2)
Excited to see this out in the world. The CGC is launching a curated strains collection, the first being protein degradation systems and this is a pilot primer to pair with it authored by myself, Dave Reiner, Ann Rougvie, and Aric Daul. We review the state of the field and provide use guidance (1)
Thanks! We were really happy with how it turned out! I got a lot of emails asking for advice about the AID system and it felt like this primer was lacking. It was great to work with Dave, Ann, and Aric and I love the idea of the curated strain collections!
What tools do we need to start engineering #aging and #longevity ? A🧵about something we've been cooking up in lab with Jeremy Vicencio at the @crg.eu : technology that lets us reach inside living animals and precisely dial multiple proteins' levels up and down. 1/10
Time to vote for our GSA officers!
Please repost
Exciting to see this work out in the world as it was one of the first projects launched when I started my lab.
Cool! Thanks @embojournal.org for this great News and Views on our recent work characterizing how a conserved protein complex times C. elegans molting! www.embopress.org/doi/full/10....
Such a fun collaboration with @labgrosshans.bsky.social @partchlab.bsky.social
Shared mechanisms across distinct biological clocks:
Jordan Ward @gotworms.bsky.social , Helge Grosshans @labgrosshans.bsky.social & collaborators find the nematode homologs of mammalian circadian clock proteins PERIOD & CK1 to control developmental timing in worms
www.embopress.org/doi/full/10....
Thanks Ethan!
So excited to see this work out! This was one of the first projects when I started my lab! An awesome collaboration with @labgrosshans.bsky.social and @partchlab.bsky.social!
Great opportunity and submissions are a little down so nominate your outstanding recent graduate, worm peeps!
For the life of me, I cannot fathom the rationale for any of this. Utter wanton destruction of one of the best research ecosystems in the world.
Cool! I hope it goes well! I had a good experience with our recent submission
There is so much cool #aECM work going on but most of the researchers don’t know or talk to each other; this is an attempt to change that! Link below
Am so excited about this series. The virtual worm skin workshop was one of the best meetings for my lab and getting more model systems will be🔥