Poeple have become one of the most important model organisms for studying evolution. Having literally millions of human genomes is changing our views of human diversity & evolution. Gene copy number variation is coming into clearer focus & we can test theories of selection or drift. 🧪
New work on Drosophila centromere evolution led by the amazing @cecilecourret.bsky.social!Thanks to all coauthors and collaborators in the @centromellone.bsky.social lab.
@leogdlima.bsky.social This is so cool and may be important for us!
Research funded by NIH generated $2.46 in economic activity for every $1 of funding in 2023 [a total of $92.9 billion]
www.fiercebiotech.com/research/rep...
@leogdlima.bsky.social
What a wonderful read about the history of discovery of GFP and its derivatives. Did you know Douglas Prasher and not Robert Tsien was the one that “cloned” the GFP gene? Read more to find out 👇🏽 #fluorescence #microscopy #cellbiology
Thank you for that wonderful piece of history.
Using microscopy to locate specific genes on chromosomes was one of Joe’s longtime dreams & the time was ripe. With graduate student Mary-Lou Pardue (Gall and Pardue, 1969; Pardue and Gall, 1969) they developed in situ hybridization, a technique that would revolutionize developmental genetics 6/n
Title and abstract of the memoriam in the Journal of Cell Biology in the link
In September the world lost one of the great biologists of our time: Joe Gall. He bridged the transition from the histology era of cell biology to our molecular present, contributing a remarkable set of insights in his 9 decades 1/n 🧪
rupress.org/jcb/article-...
Would love to be added André. Thank you!
Cartoon of man on plane with hand raised, saying “These smug pilots have lost touch with regular passengers like us. Who thinks I should fly the plane?”
I am excited to start my Bluesky board with a recent achievement. I won 1st place for the postdoctoral trainee poster award at KU Cancer Center Research Symposium where I presented my work on Detecting haplotypic asymmetries at hunan centromeres and their impact on chromosome segregation.
Excited to share our latest work! In it, we develop a new method for studying RNA localization via proximity labeling: OINC-seq! In contrast to other proximity-based methods, labels deposited on RNAs are read directly by sequencing without the need for biotinylation. biorxiv.org/cgi/content/...