Congrats to Adil Ali for getting his paper accepted at KI! He worked hard getting high-fidelity segmentation of all major structures of the kidney glomerulus, which was imaged at 100nm resolution! Check out a ton of interesting 3D data in the repository- including 3D printable files!
We were already using #cellpose to segment kidney tubules but this combination with SAM should make it even more generalizable and powerful! Very exciting!
Our new review article on "Imaging 3D cell cultures with optical microscopy" is now out in @naturemethods.bsky.social. Congrats to Huai-Ching from Jon Liu's lab at UW for leading this effort! Open-access link here: rdcu.be/eh8g0
Thanks Romain! Will be fun to build some lightsheet scopes and dive into computational analysis
Thrilled to announce that I will be joining Indiana University School of Medicine as an Assistant Professor this summer! A primary focus of my lab will be to develop technologies to study #kidney diseases in 3D at the organ-scale. Lots of fun imaging to follow!
Screen shot of the article
My annual Valentine’s post of this image that happens to land on #FluorescenceFriday this year! An axon approaching a kidney glomerulus doing its best to look like a rose.
Improvements in LM (top) and EM (bottom) of our micro-sam model (finetuned) compared to the default SAM model.
After a long journey, Segment Anything for Microscopy is now published in Nature Methods! We significantly improve SAM for interactive and automatic segmentation in light and electron microscopy and build a user-friendly tool.
www.nature.com/articles/s41...
Live footage of the average NIH-funding academic as we cycle between maybe no longer having a job and court rulings allow NIH to resume evaluating and funding grants.
I do not recommend this life style, it sucks
Most of us just want to do important science unpeturbed.
That is very cool, I'll have to try that. I have so many videos on my ppts without source files
Very cool! I wondered what the best way to transfer or move Zarr files on Windows is? Convert it to some single file zipped format?
Our work on multiplexed imaging using polymer dots made it to the cover of Science Advances! Out today and very timely for #fluorescencefriday
Paper here: www.science.org/doi/10.1126/...