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Posts by Ian Heller

I’m looking for an automated way to read others’s scientific data without giving credit or acknowledgement, and also claim full credit for insights from it. And I want it to have a fitting name

OAI: say no more

5 days ago 829 322 10 6
Species-specific oxygen sensing governs the initiation of vertebrate limb regeneration Why mammals cannot regenerate limbs like amphibians do presents a long-standing puzzle in biology. To uncover the underlying differences, we compared amputation responses of embryonic mouse (Mus musculus) and Xenopus laevis tadpole limbs. Lowering ...

🚨 Why can’t mammals regenerate limbs like frog tadpoles or salamanders?
In our new paper in @science.org , we show that species-specific oxygen sensing acts as a gatekeeper for initiating limb regeneration 🐭🐸
🔗 www.science.org/doi/10.1126/... #EvoDevo

1 week ago 262 111 21 10
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Gall of the week, a cynipid wasp gall on roses in Canada. Details in the caption.
Photo by Peter Shirley.

1 week ago 13 3 0 0

Very cool analysis on Paradise fish (Macropodus opercularis) by @nickarjones.bsky.social et al. 🐠 #TeleostTalk

3 weeks ago 2 1 0 0
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Mechanics of dust bathing in birds | PNAS Dust bathing is a widespread behavior among birds that helps remove ectoparasites, but its mechanical basis remains poorly understood. Here we show...

Does Dr. Migleemo on Lower Decks really like the sonic shower?Mechanics of dust bathing in birds | PNAS www.pnas.org/doi/abs/10.1...

3 weeks ago 1 1 1 0

It is very easy to read statements like this as a joke.

This is not a joke.

We have proven with AI, completely by accident, what knowledgeable people have been saying for decades: the environment that rich people live in gives them a very specific personality disorder.

1 month ago 6761 2636 38 40

Love to see the visuals and research people can make from this!

2 months ago 10 1 0 0
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Male Copulatory Structures in Reproductively Functional Female Live‐Bearing Fish Pseudopoecilia fria We recently discovered a population of the live-bearing fish Pseudopoecilia fria (Cyprinodontiformes: Poeciliidae), in which females were found to possess gonopodia, reproductive organs normally excl...

One of the coolest ichthyology discoveries I’ve heard about in a while. Large pregnant female livebearers with male reproductive organs found in the wild. Goes to show how fluid sex and sexual traits can be.

onlinelibrary.wiley.com/doi/10.1002/...

2 months ago 87 36 3 3
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Google Scholar Is Doomed Academia built entire careers on a free Google service with zero guarantees. What could go wrong?

Since search is dead, how soon do you think Google Scholar is headed for the Google Graveyard? I'm betting it's soon, and academia is NOT prepared

8 months ago 939 406 54 132
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High-Level, Actionable Insights From Watching Doubles Luge For The First Time | Defector To the uninitiated, luge itself might seem a silly sport, given that the average person might guess it mostly consists of holding onto a sled real tight as it goes fast down the ice. Of course, this o...

"If someone can invent a new Olympic sport by stacking one guy on top of another guy, surely someone could invent another Olympic sport by stacking yet one more guy on top of the aforementioned guys."

Important work from @sabs.bsky.social:

[🎁]

2 months ago 327 64 23 10
https://doi.org/10.1016/j.cub.2026.01.033

https://doi.org/10.1016/j.cub.2026.01.033

[New Paper] @currentbiology.bsky.social presents our population genomics study of the iconic Scaly-foot Snail: 125 genomes from 8 Indian Ocean hot vents! Deep currents drive South→North gene flow, while transform faults act as dispersal barriers.
READ FOR FREE: authors.elsevier.com/c/1mbW73QW8S...

2 months ago 91 36 1 7

Be careful, it’s a slippery slope to lotion addiction

2 months ago 1 0 0 0
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Is enhancer-driven gene regulation all wrapped up? - Nature Reviews Genetics In this Comment, Wendy Bickmore discusses mechanistic models of how 3D genome organization facilitates communication between distant enhancers and their target promoters to regulate gene expression.

Now reading.

The most important sentence (IMHO) in this wonderful paper:

"detecting enhancer–promoter ‘interactions’ does not mean that these interactions are mechanistically important" 🧪

www.nature.com/articles/s41...

2 months ago 40 5 3 0
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Time for a thread on our Christmas preprint “Origin and evolution of acrocentric chromosomes in human and great apes”. I had so much fun with this project and paper. It will be hard to summarize in a thread, but I’ll try www.biorxiv.org/content/10.6... [1/21]

2 months ago 41 29 1 1
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An ancient genome duplication event drives the development and evolution of spinnerets in spiders A genome duplication event during the Silurian played a crucial role in the evolutionary emergence of spinnerets in spiders.

Chromosome-scale #genomes from newly sequenced spiders & the whip scorpion, the genetic basis of spinneret emergence in spiders & the complex history & functional importance of arachnid genome #evolution www.science.org/doi/10.1126/... #biodiversity #genomics

2 months ago 44 18 1 1

Whoa!! I just learned that small equipment stops working when the motor brushes wear down, and that brushes are cheap and trivial to replace.

I just fixed two broken rockers and a rotator.

Damn!! This should be part of the PhD curriculum.

2 months ago 39 8 6 0

This is DISASTROUS for our country.

2 months ago 7 1 0 0
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You don't understand that's my emotional support bag of loose PCR tubes

2 months ago 37 4 3 2
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Mammals have evolved into ant eaters 12 times since the dinosaur age, study finds Mammals have developed some unusual eating habits over the past 100 million years, but a new study has uncovered the surprising lengths to which some have gone to satisfy one of the more peculiar—a ta...

Tired: Everything evolves to be a crab.

Wired: Everything evolves to eat ants.

3 months ago 552 136 23 29
Sugar cookie in the shape of a three spine stickleback, although with the most caudal dorsal spine quite a bit out of proportion due to the bakers lack of finesse.

Sugar cookie in the shape of a three spine stickleback, although with the most caudal dorsal spine quite a bit out of proportion due to the bakers lack of finesse.

A classic baking form!

4 months ago 1 0 0 0
Intro to Bedder – The Quinlan Lab

We are thrilled to announce the first official release (v0.1.8) of #𝗯𝗲𝗱𝗱𝗲𝗿, the successor to one of our flagship tool, #𝗯𝗲𝗱𝘁𝗼𝗼𝗹𝘀! Based on ideas we conceived of long ago (!), this was achieved thanks to the dedication of Brent Pedersen.

1/n

4 months ago 298 152 5 11

Presumably hazing is a concern for the meteorology subsection of Earth Science club though?

5 months ago 2 0 0 0
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Life inside rotting walnut husks » Colin Purrington's blog There’s an eastern black walnut (Juglans nigra) on my neighbor’s property that rains down fruit every fall, and I finally got curious about what species might be inside. So far I’ve found four flies, ...

After years of being curious but lazy, I finally got around to documenting what's inside the black walnuts in my yard. In the process I became obsessed with the strange wasp that hunts down the pupae of the resident flies. 🌿 #wasps #diapriidae #nature #diptera colinpurrington.com/2025/11/life...

5 months ago 150 34 11 4
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📣 Paper alert!

I am delighted that our paper exploring the impact of Neanderthal-derived variants on the activity of a disease-associated craniofacial enhancer has been published in Development today!
journals.biologists.com/dev/article/...

5 months ago 123 49 7 6
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James Watson, dead at 97, was a scientific legend and a pariah among his peers James Watson, the co-discoverer of the structure of DNA who died Thursday at 97, was a scientific legend and a pariah among his peers.

A Sharon Begley byline, almost 5 years after her death.

Upon hearing the news James Watson had died, a STAT reporter said in our Slack, "I wish I could read what Sharon would have written."

Incredible news: Sharon in fact did pre-write a Watson obit. And it is masterful and excoriating.
🧪🧬🧫

5 months ago 6030 1976 111 338
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Academics in Assyria in the 7th c BC complain that admin is preventing them from doing research and teaching

5 months ago 4441 1406 53 137
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This might be the most photogenic bat ever. What a cutie!

5 months ago 3 1 0 0
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Conservation of regulatory elements with highly diverged sequences across large evolutionary distances - Nature Genetics Combining functional genomic data from mouse and chicken with a synteny-based strategy identifies positionally conserved cis-regulatory elements in the absence of direct sequence conservation.

Regulatory elements can diverge, a lot, and maintain their function:

www.nature.com/articles/s41...

5 months ago 21 5 1 0

You’re gibbon them out?

5 months ago 1 0 1 0
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Daniel Naroditsky, Chess Grandmaster, Dies at 29 He earned the highest title in the chess world as he built a career as an accomplished chess teacher, commentator and author.

Daniel Naroditsky, a chess grandmaster, the highest title given to competitors by the International Chess Federation, and a former Junior World Champion, has died at 29.

6 months ago 113 30 16 15